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ABC transporters at the blood-brain barrier

Expert opinion on drug metabolism & toxicology, 2016-05, Vol.12 (5), p.499-508

2016

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The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

Brain, behavior, and immunity, 2018-10, Vol.73, p.21-33

2018

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Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain

Biomaterials, 2018-04, Vol.161, p.129-143

2018

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The ABC of the blood-brain barrier - regulation of drug efflux pumps

Current pharmaceutical design, 2011-09, Vol.17 (26), p.2762

2011

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Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

Journal of medicinal chemistry, 2018-02, Vol.61 (4), p.1737-1743

2018

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Potent and Selective Inhibitors of Breast Cancer Resistance Protein (ABCG2) Derived from the p-Glycoprotein (ABCB1) Modulator Tariquidar

Journal of medicinal chemistry, 2009-02, Vol.52 (4), p.1190-1197

2009

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The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier

Frontiers in cellular neuroscience, 2014-10, Vol.8, p.352-352

2014

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Glutaric aciduria type I and methylmalonic aciduria: Simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood–brain barrier and the choroid plexus

Biochimica et biophysica acta, 2010-06, Vol.1802 (6), p.552-560

2010

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Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency

Journal of neurochemistry, 2006-05, Vol.97 (3), p.899-910

2006

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Crossing the blood-brain barrier: A review on drug delivery strategies using colloidal carrier systems

Neurochemistry international, 2021-07, Vol.147, p.105017-105017, Article 105017

2021

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Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

Pharmaceuticals (Basel, Switzerland), 2019-01, Vol.12 (1), p.7

2019

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BCRP at the Blood−Brain Barrier: Genomic Regulation by 17β-Estradiol

Molecular pharmaceutics, 2010-10, Vol.7 (5), p.1835-1847

2010

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The xenoestrogens ethinylestradiol and bisphenol A regulate BCRP at the blood-brain barrier of rats

Xenobiotica, 2014-11, Vol.44 (11), p.1046-1054

2014

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Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines

Anticancer research, 2023-03, Vol.43 (3), p.1031

2023

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In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii

Planta medica, 2007-11, Vol.73 (14), p.1475-1478

2007

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Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

Biological chemistry, 2019-09, Vol.400 (10), p.1335

2019

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Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2771-2775

2017

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Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype

Journal of Crohn's and colitis, 2017-10, Vol.11 (10), p.1247-1257

2017

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17-β-Estradiol: A Powerful Modulator of Blood–Brain Barrier BCRP Activity

Journal of cerebral blood flow and metabolism, 2010-10, Vol.30 (10), p.1742-1755

2010

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A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.6897-6910

2017

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A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2)

European journal of pharmaceutics and biopharmaceutics, 2009-08, Vol.72 (3), p.605-613

2009

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Design of novel artemisinin‐like derivatives with cytotoxic and anti‐angiogenic properties

Journal of cellular and molecular medicine, 2011-05, Vol.15 (5), p.1122-1135

2011

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Cytotoxicity and P-glycoprotein modulating effects of quinolones and indoloquinazolines from Chinese herb Evodia rutaecarpa

Planta medica, 2007-12, Vol.73 (15), p.1554-1557

2007

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Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels

Planta medica, 2013-03, Vol.79 (3-4), p.214

2013

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Rapid assessment of p-glycoprotein–drug interactions at the blood–brain barrier

Analytical biochemistry, 2006-11, Vol.358 (1), p.51-58

2006

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ABC transporters at the blood-brain barrier

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain

The ABC of the blood-brain barrier - regulation of drug efflux pumps

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

Potent and Selective Inhibitors of Breast Cancer Resistance Protein (ABCG2) Derived from the p-Glycoprotein (ABCB1) Modulator Tariquidar

The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier

Glutaric aciduria type I and methylmalonic aciduria: Simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood–brain barrier and the choroid plexus

Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency

Crossing the blood-brain barrier: A review on drug delivery strategies using colloidal carrier systems

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

BCRP at the Blood−Brain Barrier: Genomic Regulation by 17β-Estradiol

The xenoestrogens ethinylestradiol and bisphenol A regulate BCRP at the blood-brain barrier of rats

Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines

In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development

Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype

17-β-Estradiol: A Powerful Modulator of Blood–Brain Barrier BCRP Activity

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2)

Design of novel artemisinin‐like derivatives with cytotoxic and anti‐angiogenic properties

Cytotoxicity and P-glycoprotein modulating effects of quinolones and indoloquinazolines from Chinese herb Evodia rutaecarpa

Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels

Rapid assessment of p-glycoprotein–drug interactions at the blood–brain barrier

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