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Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10090-10107

2012

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3534-3541

2017

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Discovery of Selective 4‑Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization

Journal of medicinal chemistry, 2014-04, Vol.57 (8), p.3484-3493

2014

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Two-directional synthesis and its use in natural product synthesis

Tetrahedron, 1995-02, Vol.51 (8), p.2167-2213

Magnuson, Steven R.

1995

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18), p.4546-4552

2014

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A Concise Total Synthesis of Dysidiolide through Application of a Dioxolenium-Mediated Diels−Alder Reaction

Journal of the American Chemical Society, 1998-02, Vol.120 (7), p.1615-1616

1998

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Prospects for kinase activity modulators in the treatment of diabetes and diabetic complications

Current topics in medicinal chemistry, 2002-09, Vol.2 (9), p.915

2002

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Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles

Tetrahedron letters, 2013-01, Vol.54 (3), p.201-204

2013

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Cyclopentannulation by an Iterative Process of Sequential Claisen Rearrangement and Enyne Radical Closure: Routes to Triquinane and Propellane Systems and Use in the Synthesis of (±)-Ceratopicanol

Journal of organic chemistry, 1996-03, Vol.61 (6), p.2095-2108

1996

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18)

2014

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ChemInform Abstract: Efficient Syntheses of 2-Fluoroalkylbenzimidazoles and -benzothiazoles

ChemInform, 2013-04, Vol.44 (16), p.no-no

2013

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Synthesis of the sesquiterpene (±)-ceratopicanol: Use of radicals derived from epoxides

Tetrahedron letters, 1995-01, Vol.36 (1), p.15-18

1995

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An Interactive Database for the Assessment of Histone Antibody Specificity

Molecular cell, 2015-08, Vol.59 (3), p.502-511

2015

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lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

Molecular cell, 2019-08, Vol.75 (3), p.523-537.e10

2019

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Transcatheter Mitral-Valve Repair in Patients with Heart Failure

The New England journal of medicine, 2018-12, Vol.379 (24), p.2307-2318

2018

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Oncologic Outcomes After Transoral Robotic Surgery: A Multi-institutional Study

JAMA otolaryngology-- head & neck surgery, 2015-12, Vol.141 (12), p.1043

2015

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Investigating Effects of Tulathromycin Metaphylaxis on the Fecal Resistome and Microbiome of Commercial Feedlot Cattle Early in the Feeding Period

Frontiers in microbiology, 2018-07, Vol.9, p.1715-1715

2018

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Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer

Annals of oncology, 2022-12, Vol.33 (12), p.1250-1268

2022

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A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors

The Journal of immunology (1950), 2013-09, Vol.191 (5), p.2205-2216

2013

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RNAi Suppression of LEAFY Gives Stable Floral Sterility, and Reduced Growth Rate and Leaf Size, in Field-Grown Poplars

Plants (Basel), 2021-08, Vol.10 (8), p.1594

2021

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Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance

Discovery of Selective 4‑Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition

GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1‑like

Two-directional synthesis and its use in natural product synthesis

Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors

A Concise Total Synthesis of Dysidiolide through Application of a Dioxolenium-Mediated Diels−Alder Reaction

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2)

Prospects for kinase activity modulators in the treatment of diabetes and diabetic complications

Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles

Cyclopentannulation by an Iterative Process of Sequential Claisen Rearrangement and Enyne Radical Closure: Routes to Triquinane and Propellane Systems and Use in the Synthesis of (±)-Ceratopicanol

Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors

ChemInform Abstract: Efficient Syntheses of 2-Fluoroalkylbenzimidazoles and -benzothiazoles

Synthesis of the sesquiterpene (±)-ceratopicanol: Use of radicals derived from epoxides

An Interactive Database for the Assessment of Histone Antibody Specificity

lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

Transcatheter Mitral-Valve Repair in Patients with Heart Failure

Oncologic Outcomes After Transoral Robotic Surgery: A Multi-institutional Study

Widespread adenine N6-methylation of active genes in fungi

Investigating Effects of Tulathromycin Metaphylaxis on the Fecal Resistome and Microbiome of Commercial Feedlot Cattle Early in the Feeding Period

Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer

A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors

RNAi Suppression of LEAFY Gives Stable Floral Sterility, and Reduced Growth Rate and Leaf Size, in Field-Grown Poplars

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