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Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative Disorders

Frontiers in neuroscience, 2018-04, Vol.12, p.249-249

2018

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An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation

Cell death & disease, 2021-10, Vol.12 (10), p.919-919, Article 919

2021

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Mitochondrial Respiration Changes in R6/2 Huntington's Disease Model Mice during Aging in a Brain Region Specific Manner

International journal of molecular sciences, 2020-07, Vol.21 (15), p.5412

2020

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A Rationale for Hypoxic and Chemical Conditioning in Huntington's Disease

International journal of molecular sciences, 2021-01, Vol.22 (2), p.582

2021

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Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease

Scientific reports, 2017-01, Vol.7 (1), p.41316-41316, Article 41316

2017

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Glycosphingolipid metabolic reprogramming drives neural differentiation

The EMBO journal, 2018-04, Vol.37 (7), p.n/a

2018

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Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8846

2020

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Inhibition of Ceramide Synthesis Reduces α-Synuclein Proteinopathy in a Cellular Model of Parkinson’s Disease

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6469

2021

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Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3528-3533

2012

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Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5956

2023

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Brain-Periphery Interactions in Huntington's Disease: Mediators and Lifestyle Interventions

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4696

2024

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New Therapeutic Drugs from Bioactive Natural Molecules: The Role of Gut Microbiota Metabolism in Neurodegenerative Diseases

Current drug metabolism, 2018-01, Vol.19 (6), p.478-489

2018

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Polysialic Acid Sustains the Hypoxia-Induced Migration and Undifferentiated State of Human Glioblastoma Cells

International journal of molecular sciences, 2022-09, Vol.23 (17), p.9563

2022

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Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington’s disease

Scientific reports, 2017-07, Vol.7 (1), p.5280-14, Article 5280

2017

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Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1

The Journal of neuroscience, 2010-03, Vol.30 (11), p.4072-4080

2010

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Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity

Nature communications, 2023-07, Vol.14 (1), p.3962-3962, Article 3962

2023

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Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis

Journal of experimental & clinical cancer research, 2019-08, Vol.38 (1), p.360-360, Article 360

2019

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Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3796

2021

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Assessment of Blood-brain Barrier Permeability by Intravenous Infusion of FITC-labeled Albumin in a Mouse Model of Neurodegenerative Disease

Journal of visualized experiments, 2017-11 (129)

2017

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Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal Models

Frontiers in neuroscience, 2016-10, Vol.10, p.457-457

2016

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The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease

Cell death & disease, 2020-07, Vol.11 (7), p.546, Article 546

2020

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De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease

Frontiers in neuroscience, 2017-12, Vol.11, p.698-698

2017

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Blood-Brain Barrier Integrity Is Perturbed in a Mecp2 -Null Mouse Model of Rett Syndrome

Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (4), p.606

2023

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Tractography of the corpus callosum in Huntington's disease

PloS one, 2013-09, Vol.8 (9), p.e73280-e73280

2013

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Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model

Frontiers in molecular neuroscience, 2019-04, Vol.12, p.100-100

2019

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Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative Disorders

An interplay between UCP2 and ROS protects cells from high-salt-induced injury through autophagy stimulation

Mitochondrial Respiration Changes in R6/2 Huntington's Disease Model Mice during Aging in a Brain Region Specific Manner

A Rationale for Hypoxic and Chemical Conditioning in Huntington's Disease

Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease

Glycosphingolipid metabolic reprogramming drives neural differentiation

Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders

Inhibition of Ceramide Synthesis Reduces α-Synuclein Proteinopathy in a Cellular Model of Parkinson’s Disease

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice

Brain-Periphery Interactions in Huntington's Disease: Mediators and Lifestyle Interventions

New Therapeutic Drugs from Bioactive Natural Molecules: The Role of Gut Microbiota Metabolism in Neurodegenerative Diseases

Polysialic Acid Sustains the Hypoxia-Induced Migration and Undifferentiated State of Human Glioblastoma Cells

Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington’s disease

Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1

Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity

Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis

Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage

Assessment of Blood-brain Barrier Permeability by Intravenous Infusion of FITC-labeled Albumin in a Mouse Model of Neurodegenerative Disease

Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal Models

The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease

De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease

Blood-Brain Barrier Integrity Is Perturbed in a Mecp2 -Null Mouse Model of Rett Syndrome

Tractography of the corpus callosum in Huntington's disease

Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model

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