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Binding to the neonatal Fc receptor enhances the pathogenicity of anti-desmoglein-3 antibodies in keratinocytes

Frontiers in immunology, 2024-10, Vol.15, p.1473637

2024

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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

Nature communications, 2022-10, Vol.13 (1), p.6073-6073, Article 6073

2022

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FcRn Antagonism Leads to a Decrease of Desmoglein-Specific B Cells: Secondary Analysis of a Phase 2 Study of Efgartigimod in Pemphigus Vulgaris and Pemphigus Foliaceus

Frontiers in immunology, 2022-05, Vol.13, p.863095-863095

2022

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Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis

Autoimmunity (Chur, Switzerland), 2022-11, Vol.55 (8), p.620-631

2022

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Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cells

Integrative biology (Cambridge), 2012-01, Vol.4 (10), p.1175-1184

2012

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Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature

Immunity, Inflammation and Disease, 2022-06, Vol.10 (6), p.e629-n/a

2022

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Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium

Journal of Virus Eradication, 2018-01, Vol.4 (1), p.55-59

2018

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HIV Reservoir Characterization Symposium

Journal of Virus Eradication, 2017-01, Vol.3 (1), p.66-68

2017

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A Functional Role for Antibodies in Tuberculosis

Cell, 2016-10, Vol.167 (2), p.433-443.e14

2016

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Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Nature medicine, 2018-10, Vol.24 (10), p.1590-1598

2018

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Fight fire with fire: Gene therapy strategies to cure HIV

Expert review of anti-infective therapy, 2017-08, Vol.15 (8), p.747-758

2017

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Neonatal Fc Receptor Inhibition Reduces Bullous Pemphigoid Anti–Basement Membrane Zone IgG Deposition and Blistering in 3-Dimensional Human Skin Equivalents

Journal of investigative dermatology, 2024-06

2024

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Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

Mucosal immunology, 2016-11, Vol.9 (6), p.1584-1595

2016

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Efgartigimod: Clinical Development of a Novel FcRn Antagonist in the Treatment of Autoimmune Diseases

Skin (Milwood, N.Y.), 2023-03, Vol.7 (2), p.s193

2023

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FcRn inhibition reduces bullous pemphigoid anti-basement membrane zone IgG deposition and blistering in 3D human skin equivalents

Journal of investigative dermatology, 2024-06

2024

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Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals

Virology (New York, N.Y.), 2011-07, Vol.415 (2), p.160-167

2011

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Prevention of SHIV transmission by topical IFN-β treatment

Mucosal immunology, 2016-11, Vol.9 (6), p.1528-1536

2016

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TLR2 activation causes no morbidity or cardiovascular failure, despite excessive systemic nitric oxide production

Cardiovascular research, 2013-10, Vol.100 (1), p.28-35

2013

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HLA-C levels impact natural killer cell subset distribution and function

Human immunology, 2016-12, Vol.77 (12), p.1147-1153

2016

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Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressors

EBioMedicine, 2019-03, Vol.41, p.443-454

2019

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HIV Reservoir Characterization Symposium: 19 September 2016, Ghent, Belgium

Journal of virus eradication, 2017-01, Vol.3 (1), p.66-68

2017

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Targeting Mucosal Fc-Fc Receptor Interactions as Vaccine Strategy against Mucosal HIV-transmission

AIDS research and human retroviruses, 2014-10, Vol.30 (S1), p.A63-A63

2014

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Altered distribution of mucosal NK cells during HIV infection

Mucosal immunology, 2012-01, Vol.5 (1), p.30-40

2012

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Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressorsResearch in context

EBioMedicine, 2019-03, Vol.41, p.443-454

2019

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Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2ib20167d

2012-09

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Binding to the neonatal Fc receptor enhances the pathogenicity of anti-desmoglein-3 antibodies in keratinocytes

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

FcRn Antagonism Leads to a Decrease of Desmoglein-Specific B Cells: Secondary Analysis of a Phase 2 Study of Efgartigimod in Pemphigus Vulgaris and Pemphigus Foliaceus

Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis

Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cells

Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature

Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium

HIV Reservoir Characterization Symposium

A Functional Role for Antibodies in Tuberculosis

Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Fight fire with fire: Gene therapy strategies to cure HIV

Neonatal Fc Receptor Inhibition Reduces Bullous Pemphigoid Anti–Basement Membrane Zone IgG Deposition and Blistering in 3-Dimensional Human Skin Equivalents

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

Efgartigimod: Clinical Development of a Novel FcRn Antagonist in the Treatment of Autoimmune Diseases

FcRn inhibition reduces bullous pemphigoid anti-basement membrane zone IgG deposition and blistering in 3D human skin equivalents

Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals

Prevention of SHIV transmission by topical IFN-β treatment

TLR2 activation causes no morbidity or cardiovascular failure, despite excessive systemic nitric oxide production

HLA-C levels impact natural killer cell subset distribution and function

Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressors

HIV Reservoir Characterization Symposium: 19 September 2016, Ghent, Belgium

Targeting Mucosal Fc-Fc Receptor Interactions as Vaccine Strategy against Mucosal HIV-transmission

Altered distribution of mucosal NK cells during HIV infection

Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressorsResearch in context

Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2ib20167d

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