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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV:Recommendation of a Working Group of the Gesellschaft fuer Umwelt-Mutationsforschung (GUM) for a Simple and Straightforward Approach to Genotoxicity Testing

Toxicological sciences, 2007-06, Vol.97 (2), p.237-240

2007

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Threshold effects in genetic toxicity: perspective of chemicals regulation in Germany

Mutation research, 2000-01, Vol.464 (1), p.117-121

2000

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Evaluation of the in vitro micronucleus test as an alternative to the in vitro chromosomal aberration assay: position of the GUM working group on the in vitro micronucleus test

Mutation research. Reviews in mutation research, 1998-02, Vol.410 (1), p.81-116

1998

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The Use of in vitro Data in Risk Assessment

Basic & clinical pharmacology & toxicology, 2005-03, Vol.96 (3), p.176-181

2005

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Letter to the Editor: A regulatory view on the discussion on the role of alternative methods in the risk assessment of chemicals in the context of REACH

Archives of toxicology, 2009, Vol.83 (1), p.9-10

2009

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MiniReview: The Use of in vitro Data in Risk Assessment

Basic & clinical pharmacology & toxicology, 2005-03, Vol.96 (3), p.176-181

2005

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In vitro micronucleus assay with Chinese hamster V79 cells — results of a collaborative study with in situ exposure to 26 chemical substances

Mutation research, 2000-07, Vol.468 (2), p.137-163

2000

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Chemically induced micronucleus formation in V79 cells—comparison of three different test approaches

Mutation research, 1999-02, Vol.439 (2), p.183-190

1999

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The use of toxicodynamics in risk assessment

Toxicology letters, 2001-03, Vol.120 (1), p.131-141

2001

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Methods for analysis of the mutagenicity of indirect mutagens/carcinogens in eukaryotic cells

Human genetics, 1980-10, Vol.56 (1), p.7-20

1980

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Genetic toxicology of trichloroethylene (TCE)

Mutation Research/Reviews in Genetic Toxicology, 1995-11, Vol.340 (1), p.1-36

1995

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Genotoxicity tests for new chemicals in Germany: routine in vitro test systems

Mutation research, 1998-10, Vol.418 (2), p.121-129

1998

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The potential use of mutation spectra in cancer related genes in genetic toxicology: a statement of a GUM working group

Mutation research, 2001-02, Vol.473 (2), p.263-267

2001

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Strategies and philosophies of genotoxicity testing: highly sophisticated versus pragmatic regulatory approaches

Mutation research, 1994-07, Vol.308 (1), p.111-112

Madle, Stephan

1994

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Das OECD-Pruefrichtlinienprogramm

Umweltwissenschaften und Schadstoff-Forschung, 1997-12, Vol.9 (6), p.387-396

1997

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The quality of genotoxicity testing of drugs. Experiences of a regulatory agency with new and old compounds

Mutagenesis, 1991-03, Vol.6 (2), p.143-149

1991

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Problem of the harmonization of philosophies for genotoxicity testing

Mutation Research/Genetic Toxicology, 1993, Vol.300 (2), p.73-76

Madle, Stephan

1993

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Das OECD-Prüfrichtlinienprogramm: Verfahrensweise in der Bundesrepublik Deutschland

Umweltwissenschaften und Schadstoff-Forschung, 1997-12, Vol.9 (6), p.387-396

1997

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Hepatocyte activation of indirect mutagens during the first days in primary culture

Mutagenesis, 1987-09, Vol.2 (5), p.337-340

1987

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Mutagenicity testing of doxylamine succinate, an antinauseant drug

Toxicology letters, 1989-10, Vol.49 (1), p.79-86

1989

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Induction of SCE by indirect mutagens in cultured rat hepatoma cells and in Chinese hamster V79 cells co-cultivated with hepatocyte primary cultures

Mutagenesis, 1988-11, Vol.3 (6), p.521-525

1988

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Letter to the Editor

Mutagenesis, 1987-01, Vol.2 (1), p.69-69

1987

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Letter to the Editor

Mutagenesis, 1987, Vol.2 (1), p.69-69

1987

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Evaluation of experimental parameters in an S9/human leukocyte SCE test with cyclophosphamide

Mutation Research/Environmental Mutagenesis and Related Subjects, 1981-10, Vol.85 (5), p.347-356

Madle, Stephan

1981

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Further investigations on the clastogenicity of paracetamol and acetylsalicylic acid in vitro

Mutation research. Mutation research letters, 1991, Vol.263 (2), p.83-92

1991

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV:Recommendation of a Working Group of the Gesellschaft fuer Umwelt-Mutationsforschung (GUM) for a Simple and Straightforward Approach to Genotoxicity Testing

Threshold effects in genetic toxicity: perspective of chemicals regulation in Germany

Evaluation of the in vitro micronucleus test as an alternative to the in vitro chromosomal aberration assay: position of the GUM working group on the in vitro micronucleus test

The Use of in vitro Data in Risk Assessment

Letter to the Editor: A regulatory view on the discussion on the role of alternative methods in the risk assessment of chemicals in the context of REACH

MiniReview: The Use of in vitro Data in Risk Assessment

In vitro micronucleus assay with Chinese hamster V79 cells — results of a collaborative study with in situ exposure to 26 chemical substances

Chemically induced micronucleus formation in V79 cells—comparison of three different test approaches

The use of toxicodynamics in risk assessment

Methods for analysis of the mutagenicity of indirect mutagens/carcinogens in eukaryotic cells

Genetic toxicology of trichloroethylene (TCE)

Genotoxicity tests for new chemicals in Germany: routine in vitro test systems

The potential use of mutation spectra in cancer related genes in genetic toxicology: a statement of a GUM working group

Strategies and philosophies of genotoxicity testing: highly sophisticated versus pragmatic regulatory approaches

Das OECD-Pruefrichtlinienprogramm

The quality of genotoxicity testing of drugs. Experiences of a regulatory agency with new and old compounds

Problem of the harmonization of philosophies for genotoxicity testing

Das OECD-Prüfrichtlinienprogramm: Verfahrensweise in der Bundesrepublik Deutschland

Hepatocyte activation of indirect mutagens during the first days in primary culture

Mutagenicity testing of doxylamine succinate, an antinauseant drug

Induction of SCE by indirect mutagens in cultured rat hepatoma cells and in Chinese hamster V79 cells co-cultivated with hepatocyte primary cultures

Letter to the Editor

Letter to the Editor

Evaluation of experimental parameters in an S9/human leukocyte SCE test with cyclophosphamide

Further investigations on the clastogenicity of paracetamol and acetylsalicylic acid in vitro

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