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Cardiac metabolism — A promising therapeutic target for heart failure

Pharmacology & therapeutics (Oxford), 2018-02, Vol.182, p.95-114

2018

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Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

Pharmacology & therapeutics (Oxford), 2021-07, Vol.223, p.107819-107819, Article 107819

2021

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Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?

Redox biology, 2023-04, Vol.60, p.102605, Article 102605

2023

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Disruption of methylarginine metabolism impairs vascular homeostasis

Nature medicine, 2007-02, Vol.13 (2), p.198-203

2007

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Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: Cause or association?

Atherosclerosis, 2012-07, Vol.223 (1), p.86-94

2012

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The Use of Wire Myography to Investigate Vascular Tone and Function

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2419, p.361

2022

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Bilateral Remote Ischaemic Conditioning in Children (BRICC) trial: protocol for a two-centre, double-blind, randomised controlled trial in young children undergoing cardiac surgery

BMJ open, 2020-10, Vol.10 (10), p.e042176-e042176

2020

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Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients

Circulation. Heart failure, 2015-05, Vol.8 (3), p.565-571

2015

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Inorganic Nitrate in Angina Study: A Randomized Double‐Blind Placebo‐Controlled Trial

Journal of the American Heart Association, 2017-09, Vol.6 (9), p.n/a

2017

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Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans

British journal of pharmacology, 2015-07, Vol.172 (13), p.3341-3352

2015

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Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

American journal of physiology. Heart and circulatory physiology, 2010-09, Vol.299 (3), p.H827-H836

2010

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Synergy between Natriuretic Peptides and Phosphodiesterase 5 Inhibitors Ameliorates Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2008-10, Vol.178 (8), p.861-869

2008

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Biological Activity of Designed Photolabile Metal Nitrosyls: Light-Dependent Activation of Soluble Guanylate Cyclase and Vasorelaxant Properties in Rat Aorta

Journal of medicinal chemistry, 2006-12, Vol.49 (25), p.7325-7330

2006

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ALDH2 polymorphism and myocardial infarction: From alcohol metabolism to redox regulation

Pharmacology & therapeutics (Oxford), 2024-05, p.108666-108666, Article 108666

2024

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Cysteine Redox Sensor in PKGIα Enables Oxidant-Induced Activation

Science (American Association for the Advancement of Science), 2007-09, Vol.317 (5843), p.1393-1397

2007

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Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

European heart journal, 2014-05, Vol.35 (19), p.1255-1262

2014

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Resistance to Endotoxic Shock in Endothelial Nitric-oxide Synthase (eNOS) Knock-out Mice

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.10040-10046

2005

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Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

Cardiovascular research, 2020-01, Vol.116 (1), p.51-62

2020

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Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.10040-10046

2005

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Cysteine redox sensor in PKGIa enables oxidant-induced activation

Science (American Association for the Advancement of Science), 2007-09, Vol.317 (5843), p.1393-1397

2007

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Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

The American journal of clinical nutrition, 2020-01, Vol.111 (1), p.79-89

2020

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Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm

British journal of pharmacology, 2016-06, Vol.173 (12), p.1911-1924

2016

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Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation

Cardiovascular research, 2018-08, Vol.114 (10), p.1313-1323

2018

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Development of Fluorinated Analogues of Perhexiline with Improved Pharmacokinetic Properties and Retained Efficacy

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2780-2789

2017

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Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo

Circulation (New York, N.Y.), 2005-02, Vol.111 (6), p.796-803

2005

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Cardiac metabolism — A promising therapeutic target for heart failure

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?

Disruption of methylarginine metabolism impairs vascular homeostasis

Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: Cause or association?

The Use of Wire Myography to Investigate Vascular Tone and Function

Bilateral Remote Ischaemic Conditioning in Children (BRICC) trial: protocol for a two-centre, double-blind, randomised controlled trial in young children undergoing cardiac surgery

Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients

Inorganic Nitrate in Angina Study: A Randomized Double‐Blind Placebo‐Controlled Trial

Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

Synergy between Natriuretic Peptides and Phosphodiesterase 5 Inhibitors Ameliorates Pulmonary Arterial Hypertension

Biological Activity of Designed Photolabile Metal Nitrosyls: Light-Dependent Activation of Soluble Guanylate Cyclase and Vasorelaxant Properties in Rat Aorta

ALDH2 polymorphism and myocardial infarction: From alcohol metabolism to redox regulation

Cysteine Redox Sensor in PKGIα Enables Oxidant-Induced Activation

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

Resistance to Endotoxic Shock in Endothelial Nitric-oxide Synthase (eNOS) Knock-out Mice

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo

Cysteine redox sensor in PKGIa enables oxidant-induced activation

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm

Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation

Development of Fluorinated Analogues of Perhexiline with Improved Pharmacokinetic Properties and Retained Efficacy

Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo

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