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The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3‑(4-(heterocyclyl)phenyl)‑1H‑indazole-5-carboxamides as Anticancer Agents

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3366-3392

2015

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Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (15), p.3562-3566

2016

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Analysis of Current Ideas and Controversies About Evolution of the Genus Homo and Its Species

Madeira, Brian Chance

2019

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The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1 H -indazole-5-carboxamides as Anticancer Agents

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3366-3392

2015

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Revisiting the hybridization processes in the Triatoma brasiliensis complex (Hemiptera, Triatominae): Interspecific genomic compatibility point to a possible recent diversification of the species grouped in this monophyletic complex

PloS one, 2021-10, Vol.16 (10), p.e0257992-e0257992

2021

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Urban Dog Parks as Sources of Canine Parasites: Contamination Rates and Pet Owner Behaviours in Lisbon, Portugal

Journal of environmental and public health, 2017-01, Vol.2017, p.5984086-7

2017

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Recommendations for the packaging and containerizing of bioinformatics software [version 2; peer review: 2 approved, 1 approved with reservations]

F1000 research, 2018-01, Vol.7, p.742

2018

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Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

Oncotarget, 2017-09, Vol.8 (41), p.69264-69280

2017

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Conservation needs to integrate knowledge across scales

Nature ecology & evolution, 2022-02, Vol.6 (2), p.118

2022

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Outcome of Patients with Aggressive B Cell Lymphomas Who Receive Second-Line Salvage Immunochemotherapy Following Treatment Failure of Intensive First-Line Immunochemotherapy

Blood, 2018-11, Vol.132 (Supplement 1), p.453-453

2018

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Development and Evaluation of a Cognitive Aid Booklet for Use in Rapid Response Scenarios

Simulation in healthcare : journal of the Society for Medical Simulation, 2019-08, Vol.14 (4), p.217

2019

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iDPP@CLEF 2023: The Intelligent Disease Progression Prediction Challenge

Advances in Information Retrieval, p.491-498

Volltextzugriff (PDF)

Recommendations for the packaging and containerizing of bioinformatics software [version 1; peer review: 2 approved with reservations]

F1000 research, 2018, Vol.7, p.742

2018

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Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement

ACS medicinal chemistry letters, 2015-05, Vol.6 (5), p.553-557

2015

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Absorption, metabolism, and excretion of [(14)C]MK-0524, a prostaglandin D(2) receptor antagonist, in humans

Drug metabolism and disposition, 2007-07, Vol.35 (7), p.1196

2007

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CapExec: Towards Transparently-Sandboxed Services

2019 15th International Conference on Network and Service Management (CNSM), 2019, p.1-5

2019

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Radiocarbon Dating Recent Volcanic Activity on Faial Island (Azores)

Radiocarbon, 1995, Vol.37 (2), p.139-147

1995

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The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3‑(4-(heterocyclyl)phenyl)‑1H‑indazole-5-carboxamides as Anticancer Agents

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1R,2S)‑2-(3-((E)‑4-(((cis)‑2,6-Dimethylmorpholino)methyl)styryl)‑1H‑indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1 R ,2 S )-2-(3-(( E )-4-((( cis )-2,6-Dimethylmorpholino)methyl)styryl)-1 H -indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK

Analysis of Current Ideas and Controversies About Evolution of the Genus Homo and Its Species

The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1 H -indazole-5-carboxamides as Anticancer Agents

The discovery of Polo-like kinase 4 inhibitors: identification of (1R,2S).2-(3-((E).4-(((cis).2,6-dimethylmorpholino)methyl)styryl). 1H.indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one (CFI-400945) as a potent, orally active antitumor agent

Revisiting the hybridization processes in the Triatoma brasiliensis complex (Hemiptera, Triatominae): Interspecific genomic compatibility point to a possible recent diversification of the species grouped in this monophyletic complex

Urban Dog Parks as Sources of Canine Parasites: Contamination Rates and Pet Owner Behaviours in Lisbon, Portugal

Recommendations for the packaging and containerizing of bioinformatics software [version 2; peer review: 2 approved, 1 approved with reservations]

Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling

Conservation needs to integrate knowledge across scales

Outcome of Patients with Aggressive B Cell Lymphomas Who Receive Second-Line Salvage Immunochemotherapy Following Treatment Failure of Intensive First-Line Immunochemotherapy

Development and Evaluation of a Cognitive Aid Booklet for Use in Rapid Response Scenarios

iDPP@CLEF 2023: The Intelligent Disease Progression Prediction Challenge

Recommendations for the packaging and containerizing of bioinformatics software [version 1; peer review: 2 approved with reservations]

Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement

Absorption, metabolism, and excretion of [(14)C]MK-0524, a prostaglandin D(2) receptor antagonist, in humans

CapExec: Towards Transparently-Sandboxed Services

Radiocarbon Dating Recent Volcanic Activity on Faial Island (Azores)

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