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Network and pathway expansion of genetic disease associations identifies successful drug targets

Scientific reports, 2020-12, Vol.10 (1), p.20970-20970, Article 20970

2020

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CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms

BMC systems biology, 2012-10, Vol.6 (1), p.133-133, Article 133

2012

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A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells

Angewandte Chemie (International ed.), 2014-06, Vol.53 (26), p.6720-6723

International ed. in English, 2014

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HLA class I binding of HBZ determines outcome in HTLV-1 infection

PLoS pathogens, 2010-09, Vol.6 (9), p.e1001117-e1001117

2010

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KIR2DL2 enhances protective and detrimental HLA class I-mediated immunity in chronic viral infection

PLoS pathogens, 2011-10, Vol.7 (10), p.e1002270

2011

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The Avidity and Lytic Efficiency of the CTL Response to HTLV-1

The Journal of immunology (1950), 2009-05, Vol.182 (9), p.5723-5729

2009

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T-cell epitope prediction: rescaling can mask biological variation between MHC molecules

PLoS computational biology, 2009-03, Vol.5 (3), p.e1000327-e1000327

2009

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Modeling Signaling Networks to Advance New Cancer Therapies

Annual review of biomedical engineering, 2015-12, Vol.17 (1), p.143-163

2015

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MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics

BMC bioinformatics, 2014-05, Vol.15 (1), p.136-136, Article 136

2014

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FIGARO-BM, a Biomarker Study of FIGARO-DKD, Reveals New Insights into the Mode of Action of Finerenone: TH-OR53

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.16-16

2023

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Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8

Journal of molecular biology, 2024-01, Vol.436 (2), p.168383-168383, Article 168383

2024

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ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction

RSC advances, 2024-04, Vol.14 (19), p.1383-1394

2024

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A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells

Angewandte Chemie, 2014-06, Vol.126 (26), p.6838-6841

2014

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Is the management of dog bite wounds evidence based? A postal survey and review of the literature

European journal of emergency medicine, 2004-12, Vol.11 (6), p.313-317

2004

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A systematic approach integrating genetics, computational biology, chemical genomics and gene editing to identify novel targets in the Type I interferon signaling pathway for autoimmune and infectious diseases

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.170-170.2

2018

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Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study

Critical care medicine, 2023-06, Vol.51 (6), p.808-816

2023

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Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients

Critical care (London, England), 2024-07, Vol.28 (1), p.240, Article 240

2024

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State-time spectrum of signal transduction logic models

Physical biology, 2012-08, Vol.9 (4), p.045003-045003

2012

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PIP₃ induces the recycling of receptor tyrosine kinases

Science signaling, 2014-01, Vol.7 (308), p.ra5

2014

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A single-cell model of PIP3 dynamics using chemical dimerization

Bioorganic & medicinal chemistry, 2015-06, Vol.23 (12), p.2868-2876

2015

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In vivo Expression of Human T-lymphotropic Virus Type 1 Basic Leucine-Zipper Protein Generates Specific CD8+ and CD4+ T-Lymphocyte Responses that Correlate with Clinical Outcome

The Journal of infectious diseases, 2011-02, Vol.203 (4), p.529-536

2011

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Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

Critical care (London, England), 2020-03, Vol.24 (1), p.96-96, Article 96

2020

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Genetic and environmental determinants of diastolic heart function

Nature Cardiovascular Research, 2022-04, Vol.1 (4), p.361-371

2022

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PIP 3 Induces the Recycling of Receptor Tyrosine Kinases

Science signaling, 2014-01, Vol.7 (308)

2014

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Modeling signaling networks with different formalisms: a preview

Methods in molecular biology (Clifton, N.J.), 2013, Vol.1021, p.89

2013

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Network and pathway expansion of genetic disease associations identifies successful drug targets

CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms

A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells

HLA class I binding of HBZ determines outcome in HTLV-1 infection

KIR2DL2 enhances protective and detrimental HLA class I-mediated immunity in chronic viral infection

The Avidity and Lytic Efficiency of the CTL Response to HTLV-1

T-cell epitope prediction: rescaling can mask biological variation between MHC molecules

Modeling Signaling Networks to Advance New Cancer Therapies

MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics

FIGARO-BM, a Biomarker Study of FIGARO-DKD, Reveals New Insights into the Mode of Action of Finerenone: TH-OR53

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8

ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction

A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells

Is the management of dog bite wounds evidence based? A postal survey and review of the literature

A systematic approach integrating genetics, computational biology, chemical genomics and gene editing to identify novel targets in the Type I interferon signaling pathway for autoimmune and infectious diseases

Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study

Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients

State-time spectrum of signal transduction logic models

PIP₃ induces the recycling of receptor tyrosine kinases

A single-cell model of PIP3 dynamics using chemical dimerization

In vivo Expression of Human T-lymphotropic Virus Type 1 Basic Leucine-Zipper Protein Generates Specific CD8+ and CD4+ T-Lymphocyte Responses that Correlate with Clinical Outcome

Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

Genetic and environmental determinants of diastolic heart function

PIP 3 Induces the Recycling of Receptor Tyrosine Kinases

Modeling signaling networks with different formalisms: a preview

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