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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

Cell metabolism, 2017-11, Vol.26 (5), p.719-737.e6

2017

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Acetylation Disfavors Tau Phase Separation

International journal of molecular sciences, 2018-05, Vol.19 (5), p.1360

2018

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Folding and Stability of α-Helical Integral Membrane Proteins

Chemical reviews, 2006-05, Vol.106 (5), p.1931-1977

MacKenzie, Kevin R

2006

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Quantitative real-time imaging of glutathione

Nature communications, 2017-07, Vol.8 (1), p.16087-16087, Article 16087

2017

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Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

Nature communications, 2021-09, Vol.12 (1), p.5579-5579, Article 5579

2021

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Fast gaze-contingent optimal decompositions for multifocal displays

ACM transactions on graphics, 2017-11, Vol.36 (6), p.1-15

2017

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Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity

Drug metabolism reviews, 2024-04, Vol.56 (2), p.97-126

2024

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Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes

Biology of reproduction, 2020-08, Vol.103 (2), p.427-436

2020

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Expanding Complex Morpholines Using Systematic Chemical Diversity

Organic letters, 2024-05, Vol.26 (17), p.3493-3497

2024

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A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

Molecules (Basel, Switzerland), 2022-05, Vol.27 (11), p.3419

2022

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Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles

Chemistry : a European journal, 2023-10, Vol.29 (55), p.e202301888-n/a

2023

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CYP3A Mediates an Unusual C(sp2)−C(sp3) Bond Cleavage via Ipso‐Addition of Oxygen in Drug Metabolism

Angewandte Chemie International Edition, 2024-06, Vol.63 (23), p.e202405197-n/a

International ed. in English, 2024

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Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (13), p.e2023784119-e2023784119

2022

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CYP3A-Mediated Carbon-Carbon Bond Cleavages in Drug Metabolism

Biomolecules (Basel, Switzerland), 2024-09, Vol.14 (9), p.1125

2024

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MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues

Drug metabolism and disposition, 2024-06, Vol.52 (7), p.673

2024

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Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis

Annals of the rheumatic diseases, 2022-02, Vol.81 (2), p.214-224

2022

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Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

European journal of pharmaceutical sciences, 2020-10, Vol.153, p.105488-105488, Article 105488

2020

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Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC–MS-Based Metabolomic Approaches

Chemical research in toxicology, 2023-08, Vol.36 (8), p.1427-1438

2023

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Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria

ACS sensors, 2017-09, Vol.2 (9), p.1257-1261

2017

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Transmembrane Domains of the Syndecan Family of Growth Factor Coreceptors Display a Hierarchy of Homotypic and Heterotypic Interactions

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20782-20787

2007

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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery

Scientific reports, 2021-01, Vol.11 (1), p.1121-17, Article 1121

2021

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The Role of Stream Restoration in Mitigating Sediment and Phosphorous Loads in Urbanizing Watersheds

Water (Basel), 2024-01, Vol.16 (2), p.363

2024

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The N‐Terminal Domain of ALS‐Linked TDP‐43 Assembles without Misfolding

Angewandte Chemie International Edition, 2017-10, Vol.56 (41), p.12590-12593

International ed. in English, 2017

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Lead Compound Development of SRC‑3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy

Journal of medicinal chemistry, 2024-04, Vol.67 (7), p.5333-5350

2024

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On-demand modular assembly for expedited PROTAC development

Expert opinion on drug discovery, 2024-07, Vol.19 (7), p.1-772

2024

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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

Acetylation Disfavors Tau Phase Separation

Folding and Stability of α-Helical Integral Membrane Proteins

Quantitative real-time imaging of glutathione

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

Fast gaze-contingent optimal decompositions for multifocal displays

Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity

Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes

Expanding Complex Morpholines Using Systematic Chemical Diversity

A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles

CYP3A Mediates an Unusual C(sp2)−C(sp3) Bond Cleavage via Ipso‐Addition of Oxygen in Drug Metabolism

Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis

CYP3A-Mediated Carbon-Carbon Bond Cleavages in Drug Metabolism

MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues

Targeting the IL-6–Yap–Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis

Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC–MS-Based Metabolomic Approaches

Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria

Transmembrane Domains of the Syndecan Family of Growth Factor Coreceptors Display a Hierarchy of Homotypic and Heterotypic Interactions

Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery

The Role of Stream Restoration in Mitigating Sediment and Phosphorous Loads in Urbanizing Watersheds

The N‐Terminal Domain of ALS‐Linked TDP‐43 Assembles without Misfolding

Lead Compound Development of SRC‑3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy

On-demand modular assembly for expedited PROTAC development

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