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Inhibitors of molecular chaperones as therapeutic agents

1, 2013

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Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa

Antimicrobial agents and chemotherapy, 2019-11, Vol.63 (11)

2019

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Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.278-292

2009

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The Catalytic Asymmetric Aldol Reaction

Angewandte Chemie (International ed.), 2000-04, Vol.39 (8), p.1352-1375

2000

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Glycosylation of Threonine of the Repeating Unit of RNA Polymerase II with β-Linked N-Acetylglucosame Leads to a Turnlike Structure

Journal of the American Chemical Society, 1998-11, Vol.120 (45), p.11567-11575

1998

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CHAPTER 9 - Discovery and Selection of NVP-HSP990 as a Clinical Candidate

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2014, p.241-258

2014

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Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars

Chemistry & biology, 2000-11, Vol.7 (11), p.873-883

2000

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Die katalysierte asymmetrische Aldolreaktion

Angewandte Chemie, 2000-04, Vol.112 (8), p.1406-1430

2000

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Chemoenzymatic Synthesis of Key Epothilone Fragments

Synthesis (Stuttgart), 1999-01, Vol.1999 (Sup. 1), p.1469-1472

Machajewski, Timothy D.

1999

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Overview of Molecular Chaperones in Health and Disease

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Discovery and Selection of NVP-HSP990 as a Clinical Candidate

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Inhibitors of the Hsp90 C-terminus

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Die katalysierte asymmetrische Aldolreaktion

Angewandte Chemie, 2000-04, Vol.112 (8), p.1406-1430

2000

Volltextzugriff (PDF)

Discovery of the Serenex Hsp90 Inhibitor, SNX5422

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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The Discovery of BIIB021 and BIIB028

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Structural Basis of Hsp90 Function

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Molecular Chaperones as Potential Therapeutic Targets for Neurological Disorders

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Hsp90 Inhibitors in Clinic

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Structure and Function of Hsp70 Molecular Chaperones

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Discovery and Development of Ganetespib

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Hsp70 Inhibitors

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Discovery of NVP-AUY922

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

The Cancer Super-chaperone Hsp90: Drug Targeting and Post-translational Regulation

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

Volltextzugriff (PDF)

Heat-shock Protein 90 as an Antimalarial Target

Inhibitors of Molecular Chaperones As Therapeutic Agents, 2013

2013

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Inhibitors of molecular chaperones as therapeutic agents

Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa

Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

The Catalytic Asymmetric Aldol Reaction

Glycosylation of Threonine of the Repeating Unit of RNA Polymerase II with β-Linked N-Acetylglucosame Leads to a Turnlike Structure

CHAPTER 9 - Discovery and Selection of NVP-HSP990 as a Clinical Candidate

Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars

Die katalysierte asymmetrische Aldolreaktion

Chemoenzymatic Synthesis of Key Epothilone Fragments

Overview of Molecular Chaperones in Health and Disease

Discovery and Selection of NVP-HSP990 as a Clinical Candidate

Inhibitors of the Hsp90 C-terminus

Die katalysierte asymmetrische Aldolreaktion

Discovery of the Serenex Hsp90 Inhibitor, SNX5422

The Discovery of BIIB021 and BIIB028

Structural Basis of Hsp90 Function

Molecular Chaperones as Potential Therapeutic Targets for Neurological Disorders

Hsp90 Inhibitors in Clinic

Structure and Function of Hsp70 Molecular Chaperones

Discovery and Development of Ganetespib

Hsp70 Inhibitors

Discovery of NVP-AUY922

The Cancer Super-chaperone Hsp90: Drug Targeting and Post-translational Regulation

Heat-shock Protein 90 as an Antimalarial Target

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