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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Environmental and molecular mutagenesis, 2014-10, Vol.55 (8), p.609-623

2014

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Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

Environmental and molecular mutagenesis, 2013-01, Vol.54 (1), p.8-18

2013

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Strategy for genotoxicity testing: Hazard identification and risk assessment in relation to in vitro testing

Mutation research, 2007-02, Vol.627 (1), p.41-58

2007

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The Future of Regulatory Toxicology: Impact of the Biotechnology Revolution

Toxicological sciences, 2003-10, Vol.75 (2), p.236-248

MACGREGOR, James T

2003

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Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: II. An Efficient Method of Monitoring Chromosomal Damage in the Rat

Toxicological sciences, 2006-11, Vol.94 (1), p.92-107

2006

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Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

Mutation research, 2004-05, Vol.549 (1), p.43-64

2004

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In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring

Environmental and molecular mutagenesis, 2000, Vol.35 (3), p.234-252

2000

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Micronuclei as an index of cytogenetic damage: Past, present, and future

Environmental and molecular mutagenesis, 1991, Vol.18 (4), p.277-291

1991

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Flow cytometric scoring of micronucleated erythrocytes: an efficient platform for assessing in vivo cytogenetic damage

Mutagenesis, 2011-01, Vol.26 (1), p.139-145

2011

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The International Workshops on Genotoxicity Testing (IWGT): History and achievements

Mutation research, 2007-02, Vol.627 (1), p.1-4

2007

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Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (7), p.3290-3295

1997

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Regulatory aspects of genotoxicity testing: from hazard identification to risk assessment

Mutation research, 2008-11, Vol.657 (1), p.84-90

2008

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Summary of major conclusions

Mutation research, 2003-10, Vol.540 (2), p.123-125

2003

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Sensitivity of the erythrocyte micronucleus assay: Dependence on number of cells scored and inter-animal variability

Mutation research, 2007-12, Vol.634 (1), p.235-240

2007

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Summary of major conclusions from the 4th IWGT, San Francisco, 9–10 September, 2005

Mutation research, 2007-02, Vol.627 (1), p.5-9

2007

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Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group

Mutation research, 2003-10, Vol.540 (2), p.177-181

2003

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Summary of major conclusions from the International Workshop on Genotoxicity Test Procedures

Environmental and molecular mutagenesis, 2000, Vol.35 (3), p.162-166

2000

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Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity

Toxicologic pathology, 2004-01, Vol.32 (1), p.106-121

2004

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Cytogenetic Damage Induced by Folate Deficiency in Mice is Enhanced by Caffeine

Proceedings of the National Academy of Sciences - PNAS, 1990-12, Vol.87 (24), p.9962-9965

1990

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Determination of tissue distribution of an intramuscular plasmid vaccine using PCR and in situ DNA hybridization

Human gene therapy, 1996-11, Vol.7 (17), p.2185-2194

1996

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In vitro human tissue models in risk assessment : Report of a consensus-building workshop

Toxicological sciences, 2001, Vol.59 (1), p.17-36

2001

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Oral treatment with trimethoprim-sulfamethoxazole and zidovudine suppresses murine accessory cell-dependent immune responses

Toxicological sciences, 2000-06, Vol.55 (2), p.335-342

2000

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Induction of hepatic mutations in lacI transgenic mice

Mutagenesis, 1993-05, Vol.8 (3), p.265-271

1993

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Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

Mutation research, 2007-10, Vol.633 (2), p.67-79

2007

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In Vivo Rodent Erythrocyte Micronucleus Assay. II. Some Aspects of Protocol Design Including Repeated Treatments, Integration With Toxicity Testing, and Automated Scoring

Environmental and molecular mutagenesis, 2000-01, Vol.35 (3), p.234-252

2000

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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

Strategy for genotoxicity testing: Hazard identification and risk assessment in relation to in vitro testing

The Future of Regulatory Toxicology: Impact of the Biotechnology Revolution

Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: II. An Efficient Method of Monitoring Chromosomal Damage in the Rat

Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring

Micronuclei as an index of cytogenetic damage: Past, present, and future

Flow cytometric scoring of micronucleated erythrocytes: an efficient platform for assessing in vivo cytogenetic damage

The International Workshops on Genotoxicity Testing (IWGT): History and achievements

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

Regulatory aspects of genotoxicity testing: from hazard identification to risk assessment

Summary of major conclusions

Sensitivity of the erythrocyte micronucleus assay: Dependence on number of cells scored and inter-animal variability

Summary of major conclusions from the 4th IWGT, San Francisco, 9–10 September, 2005

Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group

Summary of major conclusions from the International Workshop on Genotoxicity Test Procedures

Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity

Cytogenetic Damage Induced by Folate Deficiency in Mice is Enhanced by Caffeine

Determination of tissue distribution of an intramuscular plasmid vaccine using PCR and in situ DNA hybridization

In vitro human tissue models in risk assessment : Report of a consensus-building workshop

Oral treatment with trimethoprim-sulfamethoxazole and zidovudine suppresses murine accessory cell-dependent immune responses

Induction of hepatic mutations in lacI transgenic mice

Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

In Vivo Rodent Erythrocyte Micronucleus Assay. II. Some Aspects of Protocol Design Including Repeated Treatments, Integration With Toxicity Testing, and Automated Scoring

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