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Existing and Emerging Technologies for Tumor Genomic Profiling

Journal of clinical oncology, 2013-05, Vol.31 (15), p.1815-1824

MacConaill, Laura E

2013

Volltextzugriff (PDF)

Clinical Implications of the Cancer Genome

Journal of clinical oncology, 2010-12, Vol.28 (35), p.5219-5228

2010

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Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer

Archives of pathology & laboratory medicine (1976), 2017-06, Vol.141 (6), p.751-758

2017

Volltextzugriff (PDF)

Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer

European urology, 2019-07, Vol.76 (1), p.89-97

2019

Volltextzugriff (PDF)

Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling

Journal of clinical oncology, 2011-08, Vol.29 (22), p.3085-3096

2011

Volltextzugriff (PDF)

Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer

Clinical cancer research, 2020-06, Vol.26 (11), p.2565-2572

2020

Volltextzugriff (PDF)

Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing

BMC genomics, 2018-01, Vol.19 (1), p.30-30, Article 30

2018

Volltextzugriff (PDF)

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

Nature genetics, 2013-03, Vol.45 (3), p.285-289

2013

Volltextzugriff (PDF)

Recurrent BRAF mutations in Langerhans cell histiocytosis

Blood, 2010-09, Vol.116 (11), p.1919-1923

2010

Volltextzugriff (PDF)

RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors

Journal of clinical oncology, 2012-01, Vol.30 (3), p.316-321

2012

Volltextzugriff (PDF)

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

Nucleic acids research, 2015-02, Vol.43 (3), p.e19

2015

Volltextzugriff (PDF)

MAP2K1 and MAP3K1 mutations in langerhans cell histiocytosis

Genes chromosomes & cancer, 2015-06, Vol.54 (6), p.361-368

2015

Volltextzugriff (PDF)

MEK1 mutations confer resistance to MEK and B-RAF inhibition

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (48), p.20411-20416

2009

Volltextzugriff (PDF)

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing

Cancer discovery, 2012-01, Vol.2 (1), p.82-93

2012

Volltextzugriff (PDF)

Frameshift events predict anti–PD-1/L1 response in head and neck cancer

JCI insight, 2018-02, Vol.3 (4)

2018

Volltextzugriff (PDF)

Somatic activating ARAF mutations in Langerhans cell histiocytosis

Blood, 2014-05, Vol.123 (20), p.3152-3155

2014

Volltextzugriff (PDF)

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

Genome medicine, 2020-03, Vol.12 (1), p.30-22, Article 30

2020

Volltextzugriff (PDF)

Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1

PloS one, 2014-07, Vol.9 (7), p.e101283

2014

Volltextzugriff (PDF)

KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung

Journal of thoracic oncology, 2016-04, Vol.11 (4), p.496-503

2016

Volltextzugriff (PDF)

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma

BMC cancer, 2011-02, Vol.11 (1), p.60-60, Article 60

2011

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Novel genetic mutations in a sporadic port-wine stain

JAMA dermatology (Chicago, Ill.), 2014-12, Vol.150 (12), p.1336

2014

Volltextzugriff (PDF)

Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors

Pediatric blood & cancer, 2012-12, Vol.59 (7), p.1155-1157

2012

Volltextzugriff (PDF)

Genome-wide functional synergy between amplified and mutated genes in human breast cancer

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (22), p.9532-9540

2008

Volltextzugriff (PDF)

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

PloS one, 2013-09, Vol.8 (9), p.e74950-e74950

2013

Volltextzugriff (PDF)

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Existing and Emerging Technologies for Tumor Genomic Profiling

Clinical Implications of the Cancer Genome

Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer

Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer

Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling

Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer

Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

Recurrent BRAF mutations in Langerhans cell histiocytosis

RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

MAP2K1 and MAP3K1 mutations in langerhans cell histiocytosis

MEK1 mutations confer resistance to MEK and B-RAF inhibition

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing

Frameshift events predict anti–PD-1/L1 response in head and neck cancer

Somatic activating ARAF mutations in Langerhans cell histiocytosis

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1

Profiling critical cancer gene mutations in clinical tumor samples

KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma

Novel genetic mutations in a sporadic port-wine stain

Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors

Genome-wide functional synergy between amplified and mutated genes in human breast cancer

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

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