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Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5422

2023

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Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of CD1 mice

Psychopharmacology, 2022-03, Vol.239 (3), p.795-806

2022

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The biologically active compound of Withania somnifera (L.) Dunal, docosanyl ferulate, is endowed with potent anxiolytic properties but devoid of typical benzodiazepine-like side effects

Journal of psychopharmacology (Oxford), 2021-10, Vol.35 (10), p.1277-1284

2021

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Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea

Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2287420-2287420

2024

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Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.130-136

2017

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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

PloS one, 2016-01, Vol.11 (1), p.e0147225

2016

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Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.685-692

2021

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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2270183-2270183

2023

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5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

Frontiers in cellular and infection microbiology, 2023-06, Vol.13, p.1193280-1193280

2023

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Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.68-73

2017

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Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.539-548

2020

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Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.749-757

2021

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Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3821

2021

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Molecular aspects of the RT/drug interactions. Perspective of dual inhibitors

Current pharmaceutical design, 2013, Vol.19 (10), p.1850-1859

2013

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Discovery and optimization of pyrazoline derivatives as promising monoamine oxidase inhibitors

Current topics in medicinal chemistry, 2012-10, Vol.12 (20), p.2240-2257

2012

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Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors

Nucleic acids research, 2016-03, Vol.44 (5), p.2310-2322

2016

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Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.725-729

2018

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From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.55-74

2019

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A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.530-536

2009

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Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations

Molecules (Basel, Switzerland), 2015-01, Vol.20 (1), p.206-223

2015

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Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.1526-1533

2019

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Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.264-270

2017

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Selective Inhibitory Activity against MAO and Molecular Modeling Studies of 2-Thiazolylhydrazone Derivatives

Journal of medicinal chemistry, 2007-02, Vol.50 (4), p.707-712

2007

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Design, Synthesis, and Biological Evaluation of 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 Reverse Transcriptase

ChemMedChem, 2014-08, Vol.9 (8), p.1869-1879

2014

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Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function

Antimicrobial agents and chemotherapy, 2020-06, Vol.64 (7)

2020

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Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia

Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of CD1 mice

The biologically active compound of Withania somnifera (L.) Dunal, docosanyl ferulate, is endowed with potent anxiolytic properties but devoid of typical benzodiazepine-like side effects

Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea

Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms

5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function

Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

Molecular aspects of the RT/drug interactions. Perspective of dual inhibitors

Discovery and optimization of pyrazoline derivatives as promising monoamine oxidase inhibitors

Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors

Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone

Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations

Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases

Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B

Selective Inhibitory Activity against MAO and Molecular Modeling Studies of 2-Thiazolylhydrazone Derivatives

Design, Synthesis, and Biological Evaluation of 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 Reverse Transcriptase

Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function

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