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Critical review of the role of HTS in drug discovery

Drug discovery today, 2006-04, Vol.11 (7), p.277-279

Macarron, Ricardo

2006

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Identification of novel isoform-selective inhibitors within class I histone deacetylases

The Journal of pharmacology and experimental therapeutics, 2003-11, Vol.307 (2), p.720-728

2003

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Identification and Biological Characterization of Heterocyclic Inhibitors of the Hepatitis C Virus RNA-dependent RNA Polymerase

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.38322-38327

2002

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A Homogeneous Method to Measure Aminoacyl-tRNA Synthetase Aminoacylation Activity Using Scintillation Proximity Assay Technology

Analytical biochemistry, 2000-09, Vol.284 (2), p.183-190

2000

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Identification of an essential glutamate residue in the active site of endoglucanase III from Trichoderma reesei

FEBS letters, 1993-01, Vol.316 (2), p.137-140

1993

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Ultra high quality uHTS

Drug discovery today, 2003-10, Vol.8 (20), p.923-923

Macarrón, Ricardo

2003

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Mode of action of endoglucanase III from Trichoderma reesei

Biochemical journal, 1993-02, Vol.289 (3), p.867-873

1993

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Mannanase activity of Endoglucanase III from Trichoderma reesei QM9414

Biotechnology letters, 1996-05, Vol.18 (5), p.599-602

1996

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Chemical mechanism of beta-glucosidase from Trichoderma reesei QM 9414: pH-dependence of kinetic parameters

Biochemical journal, 1992-05, Vol.283 (3), p.679-682

1992

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Mechanisms of thermoinactivation of endoglucanase I from Trichoderma reesei QM 9414

Biochemical journal, 1992-10, Vol.287 (2), p.583-588

1992

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Family A cellulases: two essential tryptophan residues in endoglucanase III from Trichoderma reesei

Biochimica et biophysica acta, 1995-10, Vol.1245 (2), p.187

1995

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A standard operating procedure for assessing liquid handler performance in high-throughput screening

Journal of biomolecular screening, 2002-12, Vol.7 (6), p.554-569

2002

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Chemical modification of beta-glucosidase from Trichoderma reesei QM 9414

Journal of biochemistry (Tokyo), 1993-11, Vol.114 (5), p.754-759

1993

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Synergism of Trichoderma reesei cellulases while degrading different celluloses

Biotechnology letters, 1993, Vol.15 (1), p.71-76

1993

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The effect of triton concentration on the activity of undecaprenyl pyrophosphate synthase inhibitors

Journal of biomolecular screening, 2003-12, Vol.8 (6), p.712

2003

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Novel antibacterials: a genomics approach to drug discovery

Current drug targets. Infectious disorders, 2002-12, Vol.2 (4), p.291-308

2002

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Spontaneous aggregation of endoglucanse 1 from Trichoderma reesei QM 9414

Biotechnology and applied biochemistry, 1992, Vol.15 (3), p.236-246

1992

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Spontaneous aggregation of endoglucanase I from Trichoderma reesei QM 9414

Biotechnology and applied biochemistry, 1992-06, Vol.15 (3), p.236-246

1992

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Early treatment of obstructive apnoea and stroke outcome: a randomised controlled trial

The European respiratory journal, 2011-05, Vol.37 (5), p.1128-1136

2011

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Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2

Journal of medicinal chemistry, 2024-02, Vol.67 (4), p.3112-3126

2024

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Revolutionizing in vivo therapy with CRISPR/Cas genome editing: breakthroughs, opportunities and challenges

Frontiers in genome editing, 2024-02, Vol.6, p.1342193-1342193

2024

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Abstract 5900: INCB161734: A novel, potent, and orally bioavailable KRAS G12D selective inhibitor demonstrates antitumor activity in KRAS G12D mutant tumors

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5900-5900

2024

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Short report - Usefulness of point-of-care ultrasound in pediatric SARS-CoV-2 infection

European review for medical and pharmacological sciences, 2020-07, Vol.24 (14), p.7801

2020

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Lesión pulmonar aguda tras transfusión de concentrado de hematíes en el paciente pediátrico. Presentación de caso y revisión de la literatura

Acta pediátrica de México, 2017-11, Vol.38 (6), p.386-393

2017

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Bedside lung ultrasound in paediatric intensive care

Anales de pediatría (Barcelona, Spain : 2003), 2016-01, Vol.84 (1), p.57-59

2016

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Critical review of the role of HTS in drug discovery

Identification of novel isoform-selective inhibitors within class I histone deacetylases

Identification and Biological Characterization of Heterocyclic Inhibitors of the Hepatitis C Virus RNA-dependent RNA Polymerase

A Homogeneous Method to Measure Aminoacyl-tRNA Synthetase Aminoacylation Activity Using Scintillation Proximity Assay Technology

Identification of an essential glutamate residue in the active site of endoglucanase III from Trichoderma reesei

Ultra high quality uHTS

Mode of action of endoglucanase III from Trichoderma reesei

Mannanase activity of Endoglucanase III from Trichoderma reesei QM9414

Chemical mechanism of beta-glucosidase from Trichoderma reesei QM 9414: pH-dependence of kinetic parameters

Mechanisms of thermoinactivation of endoglucanase I from Trichoderma reesei QM 9414

Family A cellulases: two essential tryptophan residues in endoglucanase III from Trichoderma reesei

A standard operating procedure for assessing liquid handler performance in high-throughput screening

Chemical modification of beta-glucosidase from Trichoderma reesei QM 9414

Synergism of Trichoderma reesei cellulases while degrading different celluloses

The effect of triton concentration on the activity of undecaprenyl pyrophosphate synthase inhibitors

Novel antibacterials: a genomics approach to drug discovery

Spontaneous aggregation of endoglucanse 1 from Trichoderma reesei QM 9414

Spontaneous aggregation of endoglucanase I from Trichoderma reesei QM 9414

Early treatment of obstructive apnoea and stroke outcome: a randomised controlled trial

Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2

Revolutionizing in vivo therapy with CRISPR/Cas genome editing: breakthroughs, opportunities and challenges

Abstract 5900: INCB161734: A novel, potent, and orally bioavailable KRAS G12D selective inhibitor demonstrates antitumor activity in KRAS G12D mutant tumors

Short report - Usefulness of point-of-care ultrasound in pediatric SARS-CoV-2 infection

Lesión pulmonar aguda tras transfusión de concentrado de hematíes en el paciente pediátrico. Presentación de caso y revisión de la literatura

Bedside lung ultrasound in paediatric intensive care

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