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Epithelial organization, cell polarity and tumorigenesis

Trends in cell biology, 2011-12, Vol.21 (12), p.727-735

2011

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Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis

Cancer cell, 2012-11, Vol.22 (5), p.601-614

2012

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The Par3 polarity protein is an exocyst receptor essential for mammary cell survival

Nature communications, 2017-03, Vol.8 (1), p.14867-14867, Article 14867

2017

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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

Developmental cell, 2020-12, Vol.55 (5), p.558-573.e6

2020

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Epithelial Homeostasis

Current biology, 2014-09, Vol.24 (17), p.R815-R825

2014

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The PAR Proteins: Fundamental Players in Animal Cell Polarization

Developmental cell, 2007-11, Vol.13 (5), p.609-622

2007

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Transport into and out of the Nucleus

Microbiology and Molecular Biology Reviews, 2001-12, Vol.65 (4), p.570-594

MACARA, Ian G

2001

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The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules

The Journal of cell biology, 2013-12, Vol.203 (5), p.737-746

2013

Volltextzugriff (PDF)

Exocyst dynamics during vesicle tethering and fusion

Nature communications, 2018-12, Vol.9 (1), p.5140-17, Article 5140

2018

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Cell polarity in morphogenesis and metastasis

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-11, Vol.368 (1629), p.20130012

2013

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Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation

eLife, 2020-11, Vol.9

2020

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Organization and execution of the epithelial polarity programme

Nature reviews. Molecular cell biology, 2014-04, Vol.15 (4), p.225

2014

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

Genes & development, 2003-12, Vol.17 (24), p.3011-3016

2003

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Par-3 controls tight junction assembly through the Rac exchange factor Tiam1

Nature cell biology, 2005-03, Vol.7 (3), p.262-269

2005

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PTK7-Src Signaling at Epithelial Cell Contacts Mediates Spatial Organization of Actomyosin and Planar Cell Polarity

Developmental cell, 2014-04, Vol.29 (1), p.20-33

2014

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The PAR-6 Polarity Protein Regulates Dendritic Spine Morphogenesis through p190 RhoGAP and the Rho GTPase

Developmental cell, 2008-02, Vol.14 (2), p.216-226

2008

Volltextzugriff (PDF)

The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi

PloS one, 2012-11, Vol.7 (11), p.e51130-e51130

2012

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Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

Current biology, 2010-10, Vol.20 (20), p.1809-1818

2010

Volltextzugriff (PDF)

Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

The Journal of cell biology, 2010-05, Vol.189 (4), p.661-669

2010

Volltextzugriff (PDF)

Septins Regulate Actin Organization and Cell-Cycle Arrest through Nuclear Accumulation of NCK Mediated by SOCS7

Cell, 2007-09, Vol.130 (5), p.837-850

2007

Volltextzugriff (PDF)

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

Nature cell biology, 2006-03, Vol.8 (3), p.227-237

2006

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mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

The Journal of cell biology, 2005-12, Vol.171 (6), p.1061-1071

2005

Volltextzugriff (PDF)

Posttranslational modification of CENP-A influences the conformation of centromeric chromatin

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.11827-11832

2013

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

Nature cell biology, 2000-08, Vol.2 (8), p.531-539

2000

Volltextzugriff (PDF)

An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter

Cell reports (Cambridge), 2016-06, Vol.15 (10), p.2089-2096

2016

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Epithelial organization, cell polarity and tumorigenesis

Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis

The Par3 polarity protein is an exocyst receptor essential for mammary cell survival

DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

Epithelial Homeostasis

The PAR Proteins: Fundamental Players in Animal Cell Polarization

Transport into and out of the Nucleus

The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules

Exocyst dynamics during vesicle tethering and fusion

Cell polarity in morphogenesis and metastasis

Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation

Organization and execution of the epithelial polarity programme

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1

PTK7-Src Signaling at Epithelial Cell Contacts Mediates Spatial Organization of Actomyosin and Planar Cell Polarity

The PAR-6 Polarity Protein Regulates Dendritic Spine Morphogenesis through p190 RhoGAP and the Rho GTPase

The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi

Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

Septins Regulate Actin Organization and Cell-Cycle Arrest through Nuclear Accumulation of NCK Mediated by SOCS7

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

Posttranslational modification of CENP-A influences the conformation of centromeric chromatin

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter

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