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Where are the medical countermeasures against the ARS and DEARE? A current topic relative to an animal model research platform, radiation exposure context, the acute and delayed effects of acute exposure, and the FDA animal rule

International journal of radiation biology, 2023-07, Vol.99 (7), p.994-1008

MacVittie, Thomas J.

2023

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Acute gastrointestinal syndrome in high-dose irradiated mice

Health physics (1958), 2012-10, Vol.103 (4), p.383-399

2012

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Semi-Supervised Segmentation of Radiation-Induced Pulmonary Fibrosis From Lung CT Scans With Multi-Scale Guided Dense Attention

IEEE transactions on medical imaging, 2022-03, Vol.41 (3), p.531-542

2022

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Defining the Concomitant Multiple Organ Injury within the ARS and DEARE in an Animal Model Research Platform

Health physics (1958), 2020-11, Vol.119 (5), p.519-526

2020

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The MCART Consortium Animal Model Series: MCART Animal Model Refinement and MCM Development: Defining organ dose, organ-specific tissue imaging, model validation and the natural history between the acute radiation syndrome (ARS) and the delayed effects of acute radiation exposure (DEARE)

Health physics (1958), 2015-11, Vol.109 (5), p.335-341

MacVittie, Thomas J

2015

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WAG/RijCmcr rat models for injuries to multiple organs by single high dose ionizing radiation: similarities to nonhuman primates (NHP)

International journal of radiation biology, 2020-01, Vol.96 (1), p.81-92

2020

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Acute Radiation-induced GI-ARS and H-ARS in a Canine Model of Mixed Neutron/Gamma Relative to Reference Co-60 Gamma Radiation: A Retrospective Study

Health physics (1958), 2020-09, Vol.119 (3), p.351-357

2020

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Quantification of common and planar bile acids in tissues and cultured cells

Journal of lipid research, 2020-11, Vol.61 (11), p.1524-1535

2020

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Pegfilgrastim Improves Survival of Lethally Irradiated Nonhuman Primates

Radiation research, 2015-06, Vol.183 (6), p.643-655

2015

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The Hematopoietic Syndrome of the Acute Radiation Syndrome in Rhesus Macaques: A Systematic Review of the Lethal Dose Response Relationship

Health physics (1958), 2015-11, Vol.109 (5), p.342-366

2015

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Filgrastim improves survival in lethally irradiated nonhuman primates

Radiation research, 2013-01, Vol.179 (1), p.89-100

2013

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Animal models for acute radiation syndrome drug discovery

Expert opinion on drug discovery, 2015-05, Vol.10 (5), p.497-517

2015

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Recent advances in medical countermeasure development against acute radiation exposure based on the US FDA animal rule

Journal of radiological protection, 2021-12, Vol.41 (4), p.S438-S453

2021

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Metabolomics of Multiorgan Radiation Injury in Non-human Primate Model Reveals System-wide Metabolic Perturbations

Health physics (1958), 2021-10, Vol.121 (4), p.395-405

2021

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Inflation-Fixation Method for Lipidomic Mapping of Lung Biopsies by Matrix Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging

Analytical chemistry (Washington), 2016-05, Vol.88 (9), p.4788-4794

2016

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AEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent

Radiation research, 2017-03, Vol.187 (3), p.298

2017

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Rat Models of Partial-body Irradiation with Bone Marrow-sparing (Leg-out PBI) Designed for FDA Approval of Countermeasures for Mitigation of Acute and Delayed Injuries by Radiation

Health physics (1958), 2021-10, Vol.121 (4), p.419-433

2021

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The Time Course of Radiation-induced Lung Injury in a Nonhuman Primate Model of Partial-body Irradiation With Minimal Bone Marrow Sparing: Clinical and Radiographic Evidence and the Effect of Neupogen Administration

Health physics (1958), 2019-03, Vol.116 (3), p.366-382

2019

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Evidence of delayed gastrointestinal syndrome in high-dose irradiated mice

Health physics (1958), 2012-10, Vol.103 (4), p.400-410

2012

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Acute Radiation-induced Lung Injury in the Non-human Primate: A Review and Comparison of Mortality and Co-morbidities Using Models of Partial-body Irradiation with Marginal Bone Marrow Sparing and Whole Thorax Lung Irradiation

Health physics (1958), 2020-11, Vol.119 (5), p.559-587

2020

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Lung and Heart Injury in a Nonhuman Primate Model of Partial-body Irradiation with Minimal Bone Marrow Sparing: Histopathological Evidence of Lung and Heart Injury

Health physics (1958), 2019-03, Vol.116 (3), p.383-400

2019

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Acute and Chronic Kidney Injury in a Non-Human Primate Model of Partial-Body Irradiation with Bone Marrow Sparing

Radiation research, 2017-12, Vol.188 (6), p.661-751

2017

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NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation

The Journal of clinical investigation, 2014-02, Vol.124 (2), p.730-741

2014

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Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome

Health physics (1958), 2012-10, Vol.103 (4), p.343-355

2012

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Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation Syndrome

Radiation research, 2022-09, Vol.198 (3), p.221

2022

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Where are the medical countermeasures against the ARS and DEARE? A current topic relative to an animal model research platform, radiation exposure context, the acute and delayed effects of acute exposure, and the FDA animal rule

Acute gastrointestinal syndrome in high-dose irradiated mice

Semi-Supervised Segmentation of Radiation-Induced Pulmonary Fibrosis From Lung CT Scans With Multi-Scale Guided Dense Attention

Defining the Concomitant Multiple Organ Injury within the ARS and DEARE in an Animal Model Research Platform

The MCART Consortium Animal Model Series: MCART Animal Model Refinement and MCM Development: Defining organ dose, organ-specific tissue imaging, model validation and the natural history between the acute radiation syndrome (ARS) and the delayed effects of acute radiation exposure (DEARE)

WAG/RijCmcr rat models for injuries to multiple organs by single high dose ionizing radiation: similarities to nonhuman primates (NHP)

Acute Radiation-induced GI-ARS and H-ARS in a Canine Model of Mixed Neutron/Gamma Relative to Reference Co-60 Gamma Radiation: A Retrospective Study

Quantification of common and planar bile acids in tissues and cultured cells

Pegfilgrastim Improves Survival of Lethally Irradiated Nonhuman Primates

The Hematopoietic Syndrome of the Acute Radiation Syndrome in Rhesus Macaques: A Systematic Review of the Lethal Dose Response Relationship

Filgrastim improves survival in lethally irradiated nonhuman primates

Animal models for acute radiation syndrome drug discovery

Recent advances in medical countermeasure development against acute radiation exposure based on the US FDA animal rule

Metabolomics of Multiorgan Radiation Injury in Non-human Primate Model Reveals System-wide Metabolic Perturbations

Inflation-Fixation Method for Lipidomic Mapping of Lung Biopsies by Matrix Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging

AEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent

Rat Models of Partial-body Irradiation with Bone Marrow-sparing (Leg-out PBI) Designed for FDA Approval of Countermeasures for Mitigation of Acute and Delayed Injuries by Radiation

The Time Course of Radiation-induced Lung Injury in a Nonhuman Primate Model of Partial-body Irradiation With Minimal Bone Marrow Sparing: Clinical and Radiographic Evidence and the Effect of Neupogen Administration

Evidence of delayed gastrointestinal syndrome in high-dose irradiated mice

Acute Radiation-induced Lung Injury in the Non-human Primate: A Review and Comparison of Mortality and Co-morbidities Using Models of Partial-body Irradiation with Marginal Bone Marrow Sparing and Whole Thorax Lung Irradiation

Lung and Heart Injury in a Nonhuman Primate Model of Partial-body Irradiation with Minimal Bone Marrow Sparing: Histopathological Evidence of Lung and Heart Injury

Acute and Chronic Kidney Injury in a Non-Human Primate Model of Partial-Body Irradiation with Bone Marrow Sparing

NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation

Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome

Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation Syndrome

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