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Antibody Recognition of Disordered Antigens

Structure (London), 2016-01, Vol.24 (1), p.148-157

2016

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Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14815-14822

2010

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Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions

PloS one, 2015-10, Vol.10 (10), p.e0141729-e0141729

2015

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Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

eLife, 2022-09, Vol.11

2022

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Apical membrane antigen 1 as an anti-malarial drug target

Current topics in medicinal chemistry, 2011-08, Vol.11 (16), p.2039-2047

2011

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Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

International journal of molecular sciences, 2022-10, Vol.23 (19), p.11851

2022

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Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2

PloS one, 2015-03, Vol.10 (3), p.e0119899-e0119899

2015

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Stereoselective synthesis and structural elucidation of dicarba peptides

Chemical communications (Cambridge, England), 2016-01, Vol.52 (24), p.4446-4449

2016

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Antigenic Characterization of an Intrinsically Unstructured Protein, Plasmodium falciparum Merozoite Surface Protein 2

Infection and Immunity, 2012-12, Vol.80 (12), p.4177-4185

2012

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Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

PloS one, 2014-10, Vol.9 (10), p.e109674

2014

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Global Changes in Local Protein Dynamics Reduce the Entropic Cost of Carbohydrate Binding in the Arabinose-binding Protein

Journal of molecular biology, 2007-05, Vol.368 (3), p.822-832

2007

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Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate

Vaccines (Basel), 2021-08, Vol.9 (8), p.855

2021

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CoviRx: A User-Friendly Interface for Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

Data (Basel), 2022-11, Vol.7 (11), p.164

2022

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Applications of (19)F-NMR in Fragment-Based Drug Discovery

Molecules (Basel, Switzerland), 2016-07, Vol.21 (7)

2016

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Applications of 19F-NMR in Fragment-Based Drug Discovery

Molecules (Basel, Switzerland), 2016-07, Vol.21 (7), p.860

2016

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Merozoite surface protein 2 adsorbed onto acetalated dextran microparticles for malaria vaccination

International journal of pharmaceutics, 2021-01, Vol.593, p.120168-120168, Article 120168

2021

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A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

Nature structural & molecular biology, 2016-10, Vol.23 (10), p.916-920

2016

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Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

Australian journal of chemistry, 2013-01, Vol.66 (12), p.1530

2013

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A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

Nature structural & molecular biology, 2020-07, Vol.27 (7), p.615-624

2020

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Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope

Communications biology, 2018-05, Vol.1 (1), p.58-58, Article 58

2018

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Discovery and development of 2-aminobenzimidazoles as potent antimalarials

European journal of medicinal chemistry, 2021-10, Vol.221, p.113518-113518, Article 113518

2021

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Interaction of merozoite surface protein 2 with lipid membranes

FEBS letters, 2019-02, Vol.593 (3), p.288-295

2019

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Alkyne-Bridged α‑Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3222-3233

2021

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Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.14493-14523

2024

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Antibody Recognition of Disordered Antigens

Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

Apical membrane antigen 1 as an anti-malarial drug target

Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2

Use of Human Lung Tissue Models for Screening of Drugs against SARS-CoV-2 Infection

Stereoselective synthesis and structural elucidation of dicarba peptides

Antigenic Characterization of an Intrinsically Unstructured Protein, Plasmodium falciparum Merozoite Surface Protein 2

Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

Global Changes in Local Protein Dynamics Reduce the Entropic Cost of Carbohydrate Binding in the Arabinose-binding Protein

Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate

CoviRx: A User-Friendly Interface for Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

Applications of (19)F-NMR in Fragment-Based Drug Discovery

Applications of 19F-NMR in Fragment-Based Drug Discovery

Merozoite surface protein 2 adsorbed onto acetalated dextran microparticles for malaria vaccination

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope

Discovery and development of 2-aminobenzimidazoles as potent antimalarials

Interaction of merozoite surface protein 2 with lipid membranes

Alkyne-Bridged α‑Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models

Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4

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