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Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells

Scientific reports, 2018-05, Vol.8 (1), p.8001-10, Article 8001

2018

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Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (43), p.17567-17572

2012

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A human stem cell model of early Alzheimer's disease pathology in Down syndrome

Science translational medicine, 2012-03, Vol.4 (124), p.124ra29

2012

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Apoptotic Extinction of Germ Cells in Testes of Cyp26b1 Knockout Mice

Endocrinology (Philadelphia), 2007-10, Vol.148 (10), p.4560-4567

2007

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The role of CYP26 enzymes in defining appropriate retinoic acid exposure during embryogenesis

Birth defects research. A Clinical and molecular teratology, 2010-10, Vol.88 (10), p.883-894

2010

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Transcriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibility

Biochemical journal, 2005-11, Vol.392 (Pt 1), p.241-248

2005

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Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis

PloS one, 2009-10, Vol.4 (10), p.e7501-e7501

2009

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Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

Blood, 2015-12, Vol.126 (26), p.2811-2820

2015

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Analysis of Cyp26b1/Rarg compound-null mice reveals two genetically separable effects of retinoic acid on limb outgrowth

Developmental biology, 2010-03, Vol.339 (1), p.179-186

2010

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Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1

Development (Cambridge), 2003-04, Vol.130 (7), p.1449-1459

2003

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Genetic disruption of CYP26B1 severely affects development of neural crest derived head structures, but does not compromise hindbrain patterning

Developmental dynamics, 2009-03, Vol.238 (3), p.732-745

2009

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Selective and sustained inhibition of surface-bound thrombin activity by intimatan/heparin cofactor II and its relevance to assessing systemic anticoagulation in vivo, ex vivo and in vitro

Thrombosis and haemostasis, 2001-09, Vol.86 (3), p.909

2001

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Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis

Mechanisms of development, 2002, Vol.110 (1), p.173-177

2002

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Altered Hematopoiesis in Trisomy 21 As Revealed Through In Vitro Differentiation of Isogenic Human Pluripotent Cells

Blood, 2011-11, Vol.118 (21), p.921-921

2011

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Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells

Blood advances, 2017-06, Vol.1 (14), p.903-914

2017

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Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development

Mechanisms of development, 2001-09, Vol.107 (1), p.195-201

2001

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Cloning and functional characterization of the retinoic acid-catabolizing enzyme CYP26B1 in mouse development

MacLean, Glenn Alexander

2007

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ProQuest

A practical approach to classifying and managing feeding difficulties

Pediatrics (Evanston), 2015-02, Vol.135 (2), p.344

2015

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Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB‐LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations

The Plant journal : for cell and molecular biology, 2013-11, Vol.76 (3), p.530-544

2013

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Occupational therapy consensus recommendations for functional neurological disorder

Journal of neurology, neurosurgery and psychiatry, 2020-10, Vol.91 (10), p.1037

2020

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The Added Value of Circulating Tumor Cell Enumeration to Standard Markers in Assessing Prognosis in a Metastatic Castration-Resistant Prostate Cancer Population

Clinical cancer research, 2017-04, Vol.23 (8), p.1967-1973

2017

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Identification of potent, soluble, and orally active TRPV1 antagonists

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2559-2563

2011

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Circulating tumor cell (CTC) number as a response endpoint in metastatic castration resistant (mCRPC) compared with PSA across five randomized phase 3 trials

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.5007-5007

2017

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Structure–activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.892-898

2011

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Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (15), p.4652-4657

2011

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Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

A human stem cell model of early Alzheimer's disease pathology in Down syndrome

Apoptotic Extinction of Germ Cells in Testes of Cyp26b1 Knockout Mice

The role of CYP26 enzymes in defining appropriate retinoic acid exposure during embryogenesis

Transcriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibility

Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

Analysis of Cyp26b1/Rarg compound-null mice reveals two genetically separable effects of retinoic acid on limb outgrowth

Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1

Genetic disruption of CYP26B1 severely affects development of neural crest derived head structures, but does not compromise hindbrain patterning

Selective and sustained inhibition of surface-bound thrombin activity by intimatan/heparin cofactor II and its relevance to assessing systemic anticoagulation in vivo, ex vivo and in vitro

Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis

Altered Hematopoiesis in Trisomy 21 As Revealed Through In Vitro Differentiation of Isogenic Human Pluripotent Cells

Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells

Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development

Cloning and functional characterization of the retinoic acid-catabolizing enzyme CYP26B1 in mouse development

A practical approach to classifying and managing feeding difficulties

Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB‐LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations

Occupational therapy consensus recommendations for functional neurological disorder

The Added Value of Circulating Tumor Cell Enumeration to Standard Markers in Assessing Prognosis in a Metastatic Castration-Resistant Prostate Cancer Population

Identification of potent, soluble, and orally active TRPV1 antagonists

Circulating tumor cell (CTC) number as a response endpoint in metastatic castration resistant (mCRPC) compared with PSA across five randomized phase 3 trials

Structure–activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists

Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles

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