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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

Cell metabolism, 2017-11, Vol.26 (5), p.719-737.e6

2017

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Acetylation Disfavors Tau Phase Separation

International journal of molecular sciences, 2018-05, Vol.19 (5), p.1360

2018

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Quantitative real-time imaging of glutathione

Nature communications, 2017-07, Vol.8 (1), p.16087-16087, Article 16087

2017

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Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

Nature communications, 2021-09, Vol.12 (1), p.5579-5579, Article 5579

2021

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A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

Molecules (Basel, Switzerland), 2022-05, Vol.27 (11), p.3419

2022

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CYP3A-Mediated Carbon-Carbon Bond Cleavages in Drug Metabolism

Biomolecules (Basel, Switzerland), 2024-09, Vol.14 (9), p.1125

2024

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Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria

ACS sensors, 2017-09, Vol.2 (9), p.1257-1261

2017

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Transmembrane Domains of the Syndecan Family of Growth Factor Coreceptors Display a Hierarchy of Homotypic and Heterotypic Interactions

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20782-20787

2007

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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery

Scientific reports, 2021-01, Vol.11 (1), p.1121-17, Article 1121

2021

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An auto-inhibited state of protein kinase G and implications for selective activation

eLife, 2022-08, Vol.11

2022

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Folding and Stability of α-Helical Integral Membrane Proteins

Chemical reviews, 2006-05, Vol.106 (5), p.1931-1977

MacKenzie, Kevin R

2006

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A Transmembrane Helix Dimer: Structure and Implications

Science (American Association for the Advancement of Science), 1997-04, Vol.276 (5309), p.131-133

1997

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Controlling Peptide Structure with Coordination Chemistry: Robust and Reversible Peptide–Dirhodium Ligation

Chemistry : a European journal, 2009-09, Vol.15 (36), p.8961-8965

2009

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Changes in Apparent Free Energy of Helix–Helix Dimerization in a Biological Membrane Due to Point Mutations

Journal of molecular biology, 2007-08, Vol.371 (2), p.422-434

2007

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Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity

Drug metabolism reviews, 2024-04, Vol.56 (2), p.97-126

2024

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Expanding Complex Morpholines Using Systematic Chemical Diversity

Organic letters, 2024-05, Vol.26 (17), p.3493-3497

2024

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Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes

Biology of reproduction, 2020-08, Vol.103 (2), p.427-436

2020

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Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles

Chemistry : a European journal, 2023-10, Vol.29 (55), p.e202301888-n/a

2023

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CYP3A Mediates an Unusual C(sp2)−C(sp3) Bond Cleavage via Ipso‐Addition of Oxygen in Drug Metabolism

Angewandte Chemie International Edition, 2024-06, Vol.63 (23), p.e202405197-n/a

International ed. in English, 2024

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Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (13), p.e2023784119-e2023784119

2022

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MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues

Drug metabolism and disposition, 2024-06, Vol.52 (7), p.673

2024

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Structure of androcam supports specialized interactions with myosin VI

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (33), p.13290-13295

2012

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Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

European journal of pharmaceutical sciences, 2020-10, Vol.153, p.105488-105488, Article 105488

2020

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Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC–MS-Based Metabolomic Approaches

Chemical research in toxicology, 2023-08, Vol.36 (8), p.1427-1438

2023

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The N‐Terminal Domain of ALS‐Linked TDP‐43 Assembles without Misfolding

Angewandte Chemie International Edition, 2017-10, Vol.56 (41), p.12590-12593

International ed. in English, 2017

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The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

Acetylation Disfavors Tau Phase Separation

Quantitative real-time imaging of glutathione

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

CYP3A-Mediated Carbon-Carbon Bond Cleavages in Drug Metabolism

Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria

Transmembrane Domains of the Syndecan Family of Growth Factor Coreceptors Display a Hierarchy of Homotypic and Heterotypic Interactions

Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery

An auto-inhibited state of protein kinase G and implications for selective activation

Folding and Stability of α-Helical Integral Membrane Proteins

A Transmembrane Helix Dimer: Structure and Implications

Controlling Peptide Structure with Coordination Chemistry: Robust and Reversible Peptide–Dirhodium Ligation

Changes in Apparent Free Energy of Helix–Helix Dimerization in a Biological Membrane Due to Point Mutations

Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity

Expanding Complex Morpholines Using Systematic Chemical Diversity

Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes

Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles

CYP3A Mediates an Unusual C(sp2)−C(sp3) Bond Cleavage via Ipso‐Addition of Oxygen in Drug Metabolism

Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis

MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues

Structure of androcam supports specialized interactions with myosin VI

Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC–MS-Based Metabolomic Approaches

The N‐Terminal Domain of ALS‐Linked TDP‐43 Assembles without Misfolding

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