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Stochastic initiation of DNA replication across the human genome

Molecular cell, 2021-07, Vol.81 (14), p.2873-2874

MacAlpine, David M.

2021

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DNA replication origins-where do we begin?

Genes & development, 2016-08, Vol.30 (15), p.1683-1697

2016

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Co-orientation of replication and transcription preserves genome integrity

PLoS genetics, 2010-01, Vol.6 (1), p.e1000810-e1000810

2010

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Chromatin and DNA replication

Cold Spring Harbor perspectives in biology, 2013-08, Vol.5 (8), p.a010207-a010207

2013

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Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly

Genes & development, 2015-01, Vol.29 (2), p.212-224

2015

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Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

Genome research, 2014-11, Vol.24 (11), p.1751

2014

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Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

Genome research, 2010-02, Vol.20 (2), p.201

2010

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Epigenome characterization at single base-pair resolution

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (45), p.18318-18323

2011

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Capturing the primordial Kras mutation initiating urethane carcinogenesis

Nature communications, 2020-04, Vol.11 (1), p.1800-12, Article 1800

2020

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Conserved nucleosome positioning defines replication origins

Genes & development, 2010-04, Vol.24 (8), p.748-753

2010

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Chromatin signatures of the Drosophila replication program

Genome research, 2011-02, Vol.21 (2), p.164

2011

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Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

Genes & development, 2021-10, Vol.35 (19-20), p.1339-1355

2021

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Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle

The EMBO journal, 2015-02, Vol.34 (4), p.531-543

2015

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Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats

PLoS genetics, 2019-05, Vol.15 (5), p.e1008138-e1008138

2019

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Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork

Genome research, 2019-07, Vol.29 (7), p.1123

2019

Volltextzugriff (PDF)

Linking the dynamics of chromatin occupancy and transcription with predictive models

Genome research, 2021-06, Vol.31 (6), p.1035

2021

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ORChestrating the human DNA replication program

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (33), p.9136-9138

MacAlpine, David M.

2016

Volltextzugriff (PDF)

Expression in aneuploid Drosophila S2 cells

PLoS biology, 2010-02, Vol.8 (2), p.e1000320-e1000320

2010

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Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

Genome research, 2021-05, Vol.31 (5), p.775

2021

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Rare Codons Regulate KRas Oncogenesis

Current biology, 2013-01, Vol.23 (1), p.70-75

2013

Volltextzugriff (PDF)

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

Genes & development, 2004-06, Vol.18 (11), p.1263-1271

2004

Volltextzugriff (PDF)

Unlocking the secrets of the genome

Nature (London), 2009-06, Vol.459 (7249), p.927-930

2009

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Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

Genome research, 2018-11, Vol.28 (11), p.1688

2018

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Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate

Molecular and cellular biology, 2015-06, Vol.35 (12), p.2131-2143

2015

Volltextzugriff (PDF)

RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data

Nucleic acids research, 2021-08, Vol.49 (14), p.7925

2021

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Stochastic initiation of DNA replication across the human genome

DNA replication origins-where do we begin?

Co-orientation of replication and transcription preserves genome integrity

Chromatin and DNA replication

Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

Epigenome characterization at single base-pair resolution

Capturing the primordial Kras mutation initiating urethane carcinogenesis

Conserved nucleosome positioning defines replication origins

Chromatin signatures of the Drosophila replication program

Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle

Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats

Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork

Linking the dynamics of chromatin occupancy and transcription with predictive models

ORChestrating the human DNA replication program

Expression in aneuploid Drosophila S2 cells

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

Rare Codons Regulate KRas Oncogenesis

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

Unlocking the secrets of the genome

Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate

RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data

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