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Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Nature communications, 2021-09, Vol.12 (1), p.5302-5302, Article 5302

2021

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Author Correction: Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Nature communications, 2023-03, Vol.14 (1), p.1536-1536, Article 1536

2023

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Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane

The Journal of biological chemistry, 2015-11, Vol.290 (46), p.27972-27985

2015

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Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions

The Journal of immunology (1950), 2015-07, Vol.195 (2), p.706-716

2015

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Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions

Nature communications, 2019-07, Vol.10 (1), p.3134-16, Article 3134

2019

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Dual Topology of the Melanocortin-2 Receptor Accessory Protein Is Stable

Frontiers in endocrinology (Lausanne), 2016-07, Vol.7, p.96-96

2016

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Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets

Immunology, 2011-03, Vol.132 (3), p.348-360

2011

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Allosteric Inhibitor of ERAP1 Acts by Stabilizing a Closed Conformation

The FASEB journal, 2018-04, Vol.32 (S1), p.527.11-527.11

2018

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A broadly applicable approach to T cell epitope identification: Application to improving tumor associated epitopes and identifying epitopes in complex pathogens

Journal of immunological methods, 2011-10, Vol.373 (1-2), p.111-126

2011

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Molecular pathways for antigenic peptide generation by ER aminopeptidase 1

Molecular immunology, 2019-09, Vol.113, p.50-57

2019

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Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition

ACS chemical biology, 2022-07, Vol.17 (7), p.1756-1768

2022

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Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1

Biochemistry (Easton), 2017-03, Vol.56 (10), p.1546-1558

2017

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Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.103-121

2020

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Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

Cancer Immunology, Immunotherapy, 2019-08, Vol.68 (8), p.1245-1261

2019

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Chemical inhibition of ER aminopeptidase 1 as a tool for regulating the immunopeptidome of cancer cells

Molecular immunology, 2022-10, Vol.150, p.13

2022

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Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

ACS medicinal chemistry letters, 2020-07, Vol.11 (7), p.1429-1434

2020

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Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

The Journal of biological chemistry, 2021-10, Vol.297 (4), p.101102-101102, Article 101102

2021

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Evaluating the role of HLA-DM in MHC II-peptide association reactions1

The Journal of immunology (1950), 2015-06, Vol.195 (2), p.706-716

2015

Volltextzugriff (PDF)

Critical role of inter-domain interactions on the conformational change and catalytic mechanism of Endoplasmic Reticulum Aminopeptidase 1

Biochemistry (Easton), 2017-03, Vol.56 (10), p.1546-1558

2017

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Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia

Blood, 2019-11, Vol.134 (Supplement_1), p.964-964

2019

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Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets: T-cell epitope discovery in F. tularensis SchuS4

Immunology, 2011-03, Vol.132 (3), p.348-360

2011

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Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Author Correction: Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane

Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions

Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions

Dual Topology of the Melanocortin-2 Receptor Accessory Protein Is Stable

Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets

Allosteric Inhibitor of ERAP1 Acts by Stabilizing a Closed Conformation

A broadly applicable approach to T cell epitope identification: Application to improving tumor associated epitopes and identifying epitopes in complex pathogens

Molecular pathways for antigenic peptide generation by ER aminopeptidase 1

Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition

Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1

Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

Chemical inhibition of ER aminopeptidase 1 as a tool for regulating the immunopeptidome of cancer cells

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

Evaluating the role of HLA-DM in MHC II-peptide association reactions1

Critical role of inter-domain interactions on the conformational change and catalytic mechanism of Endoplasmic Reticulum Aminopeptidase 1

Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia

Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets: T-cell epitope discovery in F. tularensis SchuS4

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