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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

Circulation (New York, N.Y.), 2021-06, Vol.143 (22), p.2188-2204

2021

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Ketone therapy for heart failure: current evidence for clinical use

Cardiovascular research, 2022-03, Vol.118 (4), p.977-987

2022

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The molecular mechanisms that underpin the biological benefits of full-spectrum cannabis extract in the treatment of neuropathic pain and inflammation

Biochimica et biophysica acta. Molecular basis of disease, 2020-07, Vol.1866 (7), p.165771-165771, Article 165771

2020

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Insight into the physiological and pathological roles of the aryl hydrocarbon receptor pathway in glucose homeostasis, insulin resistance, and diabetes development

Cellular & molecular biology letters, 2022-11, Vol.27 (1), p.103-26, Article 103

2022

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Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure

Circulation. Heart failure, 2020-01, Vol.13 (1), p.e006277-e006277

2020

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The beneficial effects of reducing NLRP3 inflammasome activation in the cardiotoxicity and the anti-cancer effects of doxorubicin

Archives of toxicology, 2021-01, Vol.95 (1), p.1-9

2021

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C7ORF41 Regulates Inflammation by Inhibiting NF-κB Signaling Pathway

BioMed research international, 2021, Vol.2021, p.7413605-7

2021

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Empagliflozin suppresses inflammation and protects against acute septic renal injury

Inflammopharmacology, 2021-02, Vol.29 (1), p.269-279

2021

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Resveratrol reduces cardiac NLRP3‐inflammasome activation and systemic inflammation to lessen doxorubicin‐induced cardiotoxicity in juvenile mice

FEBS letters, 2021-06, Vol.595 (12), p.1681-1695

2021

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Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis

Biochimica et biophysica acta. Molecular basis of disease, 2022-11, Vol.1868 (11), p.166507-166507, Article 166507

2022

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Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation

American journal of physiology. Heart and circulatory physiology, 2021-01, Vol.320 (1), p.H432-H446

2021

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Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure

Circulation. Heart failure, 2020-06, Vol.13 (6), p.e006573-e006573

2020

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The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis

Inflammation research, 2020-06, Vol.69 (6), p.549-558

2020

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Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes

Environmental pollution (1987), 2013-10, Vol.181, p.226-232

2013

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6‑Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation

Chemical research in toxicology, 2023-03, Vol.36 (3), p.552-560

2023

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Fluconazole Represses Cytochrome P450 1B1 and Its Associated Arachidonic Acid Metabolites in the Heart and Protects Against Angiotensin II-Induced Cardiac Hypertrophy

Journal of pharmaceutical sciences, 2020-07, Vol.109 (7), p.2321-2335

2020

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Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development

Cellular & molecular biology letters, 2024-03, Vol.29 (1), p.33-33, Article 33

2024

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Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity

Molecular biology reports, 2024-12, Vol.51 (1), p.859, Article 859

2024

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The pharmacological effects of inhaled cannabis on pain in patients with multiple sclerosis: risks versus rewards

Inflammation research, 2020-11, Vol.69 (11), p.1073-1076

2020

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Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

BMC cancer, 2020-08, Vol.20 (1), p.751-13, Article 751

2020

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Resveratrol improves cardiac function and exercise performance in MI-induced heart failure through the inhibition of cardiotoxic HETE metabolites

Journal of molecular and cellular cardiology, 2018-12, Vol.125, p.162-173

2018

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Assessment of Native Myocardial T1 Mapping for Early Detection of Anthracycline-Induced Cardiotoxicity in Patients with Cancer: a Systematic Review and Meta-analysis

Cardiovascular toxicology, 2024-06, Vol.24 (6), p.563-575

2024

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The role of aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in glioma

Current pharmaceutical design, 2013-12, Vol.19 (40), p.7155-7166

2013

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5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism

Archives of toxicology, 2016-02, Vol.90 (2), p.359-373

2016

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Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders

ACS pharmacology & translational science, 2024-03, Vol.7 (3), p.546-559

2024

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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

Ketone therapy for heart failure: current evidence for clinical use

The molecular mechanisms that underpin the biological benefits of full-spectrum cannabis extract in the treatment of neuropathic pain and inflammation

Insight into the physiological and pathological roles of the aryl hydrocarbon receptor pathway in glucose homeostasis, insulin resistance, and diabetes development

Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure

The beneficial effects of reducing NLRP3 inflammasome activation in the cardiotoxicity and the anti-cancer effects of doxorubicin

C7ORF41 Regulates Inflammation by Inhibiting NF-κB Signaling Pathway

Empagliflozin suppresses inflammation and protects against acute septic renal injury

Resveratrol reduces cardiac NLRP3‐inflammasome activation and systemic inflammation to lessen doxorubicin‐induced cardiotoxicity in juvenile mice

Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis

Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation

Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure

The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis

Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes

6‑Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation

Fluconazole Represses Cytochrome P450 1B1 and Its Associated Arachidonic Acid Metabolites in the Heart and Protects Against Angiotensin II-Induced Cardiac Hypertrophy

Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development

Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity

The pharmacological effects of inhaled cannabis on pain in patients with multiple sclerosis: risks versus rewards

Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

Resveratrol improves cardiac function and exercise performance in MI-induced heart failure through the inhibition of cardiotoxic HETE metabolites

Assessment of Native Myocardial T1 Mapping for Early Detection of Anthracycline-Induced Cardiotoxicity in Patients with Cancer: a Systematic Review and Meta-analysis

The role of aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in glioma

5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism

Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders

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