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Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions

Pharmacological reviews, 2013-04, Vol.65 (2), p.670

2013

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Recent Patents in Allergy/Immunology: Use of arginase inhibitors in the treatment of asthma and allergic rhinitis

Allergy (Copenhagen), 2019-06, Vol.74 (6), p.1206-1208

2019

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Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

British journal of pharmacology, 2009-10, Vol.158 (3), p.652-664

2009

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Arginine Therapy for Lung Diseases

Frontiers in pharmacology, 2021-03, Vol.12, p.627503

2021

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Allosteric modulator potentiates β2AR agonist-promoted bronchoprotection in asthma models

The Journal of clinical investigation, 2023-09, Vol.133 (18), p.1-13

2023

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Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices

PloS one, 2013-06, Vol.8 (6), p.e65580

2013

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Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

Respiratory research, 2016-02, Vol.17 (14), p.13-13, Article 13

2016

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Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease

PloS one, 2012-02, Vol.7 (2), p.e31574-e31574

2012

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Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke

The FASEB journal, 2014-11, Vol.28 (11), p.4617-4628

2014

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A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

American journal of physiology. Lung cellular and molecular physiology, 2015-04, Vol.308 (8), p.L766-L775

2015

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Muscarinic receptors on airway mesenchymal cells: Novel findings for an ancient target

Pulmonary pharmacology & therapeutics, 2013-02, Vol.26 (1), p.145-155

2013

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Arginase Inhibition Protects against Allergen-induced Airway Obstruction, Hyperresponsiveness, and Inflammation

American journal of respiratory and critical care medicine, 2008-09, Vol.178 (6), p.565-573

2008

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Epac as a novel effector of airway smooth muscle relaxation

Journal of cellular and molecular medicine, 2011-07, Vol.15 (7), p.1551-1563

2011

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Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung

Pharmaceuticals, 2012-11, Vol.5 (12), p.1291-1331

2012

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Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma

Respiratory research, 2006-01, Vol.7 (1), p.6-6, Article 6

2006

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β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase

Naunyn-Schmiedeberg's archives of pharmacology, 2015-07, Vol.388 (7), p.749-759

2015

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Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction

Cells (Basel, Switzerland), 2021-05, Vol.10 (5), p.1237

2021

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A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.356

2020

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cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A

British journal of pharmacology, 2011-01, Vol.162 (1), p.193-209

2011

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Models to study airway smooth muscle contraction in vivo , ex vivo and in vitro : Implications in understanding asthma

Pulmonary pharmacology & therapeutics, 2013-02, Vol.26 (1), p.24-36

2013

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Airway contractility and remodeling: Links to asthma symptoms

Pulmonary pharmacology & therapeutics, 2013-02, Vol.26 (1), p.3-12

2013

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Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle

Frontiers in cell and developmental biology, 2020-04, Vol.8, p.165-165

2020

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Increased arginase activity underlies allergen‐induced deficiency of cNOS‐derived nitric oxide and airway hyperresponsiveness

British journal of pharmacology, 2002-06, Vol.136 (3), p.391-398

2002

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Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling

Pulmonary circulation, 2017-03, Vol.7 (1), p.219-231

2017

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Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation

Respiratory research, 2005-03, Vol.6 (1), p.23-23, Article 23

2005

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Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions

Recent Patents in Allergy/Immunology: Use of arginase inhibitors in the treatment of asthma and allergic rhinitis

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

Arginine Therapy for Lung Diseases

Allosteric modulator potentiates β2AR agonist-promoted bronchoprotection in asthma models

Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices

Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease

Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke

A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Muscarinic receptors on airway mesenchymal cells: Novel findings for an ancient target

Arginase Inhibition Protects against Allergen-induced Airway Obstruction, Hyperresponsiveness, and Inflammation

Epac as a novel effector of airway smooth muscle relaxation

Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung

Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma

β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase

Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction

A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition

cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A

Models to study airway smooth muscle contraction in vivo , ex vivo and in vitro : Implications in understanding asthma

Airway contractility and remodeling: Links to asthma symptoms

Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle

Increased arginase activity underlies allergen‐induced deficiency of cNOS‐derived nitric oxide and airway hyperresponsiveness

Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling

Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation

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