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Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans

PloS one, 2023-06, Vol.18 (6), p.e0287558-e0287558

2023

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Protein methylation in mitochondria

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101791-101791, Article 101791

2022

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The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

Nature communications, 2018-08, Vol.9 (1), p.3411-15, Article 3411

2018

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Human seven-β-strand (METTL) methyltransferases - conquering the universe of protein lysine methylation

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104661-104661, Article 104661

2023

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Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons

Nature communications, 2022-08, Vol.13 (1), p.4883-4883, Article 4883

2022

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Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation

Nucleic acids research, 2017-08, Vol.45 (14), p.8239-8254

2017

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The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

Nucleic acids research, 2020-01, Vol.48 (2), p.830-846

2020

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Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease

British journal of haematology, 2018-12, Vol.183 (5), p.838-842

2018

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Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis

Molecular biology of the cell, 2008-08, Vol.19 (8), p.3390-3403

2008

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The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

Nucleic acids research, 2017-05, Vol.45 (8), p.4370

2017

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Protein lysine methylation by seven-β-strand methyltransferases

Biochemical journal, 2016-07, Vol.473 (14), p.1995-2009

2016

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Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation

RNA biology, 2018-03, Vol.15 (3), p.314-319

2018

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Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase

PloS one, 2015-06, Vol.10 (6), p.e0131426-e0131426

2015

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Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase

The Journal of biological chemistry, 2019-01, Vol.294 (4), p.1128-1141

2019

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Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease

Clinical and experimental immunology, 2024-03, Vol.216 (1), p.45-54

2024

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Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation

The Journal of biological chemistry, 2017-10, Vol.292 (43), p.17950-17962

2017

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Human METTL20 Is a Mitochondrial Lysine Methyltransferase That Targets the β Subunit of Electron Transfer Flavoprotein (ETFβ) and Modulates Its Activity

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.423-434

2015

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Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity

Haematologica (Roma), 2016-09, Vol.101 (9), p.e361-e364

2016

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The METTL20 Homologue from Agrobacterium tumefaciens Is a Dual Specificity Protein-lysine Methyltransferase That Targets Ribosomal Protein L7/L12 and the β Subunit of Electron Transfer Flavoprotein (ETFβ)

The Journal of biological chemistry, 2016-04, Vol.291 (18), p.9581-9595

2016

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The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels

American journal of hematology, 2021-08, Vol.96 (8), p.E279-E283

2021

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Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Nucleic acids research, 2021-04, Vol.49 (6), p.3185-3203

2021

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Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration

The Journal of biological chemistry, 2019-08, Vol.294 (31), p.11654-11664

2019

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Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis

Melanoma research, 2010-02, Vol.20 (1), p.52-58

2010

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The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Nature communications, 2021-02, Vol.12 (1), p.891-891, Article 891

2021

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Gene Expression Analysis Reveals Downregulation of Complement Receptor 1 in Cold Agglutinin Disease

Blood, 2022-11, Vol.140 (Supplement 1), p.6419-6420

2022

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Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans

Protein methylation in mitochondria

The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

Human seven-β-strand (METTL) methyltransferases - conquering the universe of protein lysine methylation

Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons

Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease

Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

Protein lysine methylation by seven-β-strand methyltransferases

Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation

Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase

Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase

Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease

Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation

Human METTL20 Is a Mitochondrial Lysine Methyltransferase That Targets the β Subunit of Electron Transfer Flavoprotein (ETFβ) and Modulates Its Activity

Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity

The METTL20 Homologue from Agrobacterium tumefaciens Is a Dual Specificity Protein-lysine Methyltransferase That Targets Ribosomal Protein L7/L12 and the β Subunit of Electron Transfer Flavoprotein (ETFβ)

The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration

Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Gene Expression Analysis Reveals Downregulation of Complement Receptor 1 in Cold Agglutinin Disease

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