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Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

Circulation (New York, N.Y.), 2012-06, Vol.125 (25), p.3170-3181

2012

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Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (50), p.32105-32113

2020

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Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury

Autophagy, 2015-09, Vol.11 (9), p.1537-1560

2015

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Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease

The Journal of clinical investigation, 2022-06, Vol.132 (11)

2022

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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death

Autophagy, 2012-03, Vol.8 (3), p.297-309

2012

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Autophagy is impaired in cardiac ischemia-reperfusion injury

Autophagy, 2012-09, Vol.8 (9), p.1394-1396

2012

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IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions

Science signaling, 2015-06, Vol.8 (382), p.ra62

2015

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Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization

Journal of the American Heart Association, 2019-02, Vol.8 (4), p.e010866-e010866

2019

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Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy

Circulation. Heart failure, 2015-01, Vol.8 (1), p.175-187

2015

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Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

PLoS biology, 2019-05, Vol.17 (5), p.e3000245-e3000245

2019

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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

Cell metabolism, 2016-07, Vol.24 (1), p.158-166

2016

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Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

The Journal of neuroscience, 2015-09, Vol.35 (35), p.12137-12151

2015

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Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis

The Journal of neuroscience, 2014-07, Vol.34 (29), p.9607-9620

2014

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INTERMITTENT FASTING RESCUES LIPID OVERLOAD CARDIOMYOPATHY VIA NOVEL MECHANISMS

Journal of the American College of Cardiology, 2022-03, Vol.79 (9), p.3479

2022

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Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway

Autophagy, 2017-11, Vol.13 (11), p.1952-1968

2017

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Abstract 17015: Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter

Biochemical journal, 2005-06, Vol.388 (Pt 3), p.913-920

2005

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Regulation of the Transcription Factor EB-PGC1α Axis by Beclin-1 Controls Mitochondrial Quality and Cardiomyocyte Death under Stress

Molecular and cellular biology, 2015-03, Vol.35 (6), p.956-976

2015

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Neonatal intravenous injection of a gammaretroviral vector has a low incidence of tumor induction in mice

Human gene therapy, 2008-11, Vol.19 (11), p.1317-1323

2008

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Abstract 14114: Role of Toxic Protein Sequestration by Aggregates in Cardiac Myocytes in Ischemic Cardiomyopathy

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Peripheral monocyte–derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease

The Journal of clinical investigation, 2022-06, Vol.132 (11), p.1-9

2022

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Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor

Circulation. Heart failure, 2017-12, Vol.10 (12)

2017

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Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure

JACC. Basic to translational science, 2022-12, Vol.7 (12), p.1214-1228

2022

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Abstract 9176: Enhancing Lysosome Biogenesis Attenuates Bnip3-induced Cardiomyocyte Death

Circulation (New York, N.Y.), 2011-11, Vol.124 (suppl_21)

2011

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TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis

JACC. Basic to translational science, 2022-03, Vol.7 (3), p.223-243

2022

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Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury

Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease

Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death

Autophagy is impaired in cardiac ischemia-reperfusion injury

IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions

Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization

Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis

INTERMITTENT FASTING RESCUES LIPID OVERLOAD CARDIOMYOPATHY VIA NOVEL MECHANISMS

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway

Abstract 17015: Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function

Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter

Regulation of the Transcription Factor EB-PGC1α Axis by Beclin-1 Controls Mitochondrial Quality and Cardiomyocyte Death under Stress

Neonatal intravenous injection of a gammaretroviral vector has a low incidence of tumor induction in mice

Abstract 14114: Role of Toxic Protein Sequestration by Aggregates in Cardiac Myocytes in Ischemic Cardiomyopathy

Peripheral monocyte–derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease

Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor

Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure

Abstract 9176: Enhancing Lysosome Biogenesis Attenuates Bnip3-induced Cardiomyocyte Death

TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis

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