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AKAP150 and its Palmitoylation Contributed to Pain Hypersensitivity Via Facilitating Synaptic Incorporation of GluA1-Containing AMPA Receptor in Spinal Dorsal Horn

Molecular neurobiology, 2021-12, Vol.58 (12), p.6505-6519

2021

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Ligustilide covalently binds to Cys129 of HMGCS1 to ameliorate dyslipidemia

Biomedicine & pharmacotherapy, 2023-10, Vol.166, p.115323-115323, Article 115323

2023

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Atractylenolide-I covalently binds to CYP11B2, selectively inhibits aldosterone synthesis, and improves hyperaldosteronism

Acta pharmaceutica Sinica. B, 2022-01, Vol.12 (1), p.135-148

2022

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Qingfei Xiaoyan Wan,a traditional Chinese medicine formula, ameliorates Pseudomonas aeruginosa–induced acute lung inflammation by regulation of PI3K/AKT and Ras/MAPK pathways

Acta pharmaceutica Sinica. B, 2016-05, Vol.6 (3), p.212-221

2016

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The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism

Journal of functional foods, 2021-07, Vol.82, p.104501, Article 104501

2021

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Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics

Metabolites, 2022-01, Vol.12 (2), p.121

2022

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Analyze and Identify Peiminine Target EGFR Improve Lung Function and Alleviate Pulmonary Fibrosis to Prevent Exacerbation of Chronic Obstructive Pulmonary Disease by Phosphoproteomics Analysis

Frontiers in pharmacology, 2019-07, Vol.10, p.737-737

2019

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Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells

Journal of functional foods, 2019-04, Vol.55, p.296-304

2019

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Sign Learning Kink-based (SiLK) Quantum Monte Carlo for molecular systems

The Journal of chemical physics, 2016-01, Vol.144 (1), p.014101-014101

2016

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Micro-PET Imaging Demonstrates 3-O-β-D-Glucopyranosyl Platycodigenin as an Effective Metabolite Affects Permeability of Cell Membrane and Improves Dosimetry of [18F]-Phillygenin in Lung Tissue

Frontiers in pharmacology, 2019-09, Vol.10, p.1020-1020

2019

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Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins

Acta pharmaceutica Sinica. B, 2019-03, Vol.9 (2), p.294-303

2019

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3,5-Dimethyl-8-methoxy-3,4-dihydro‑1H‑isochromen-6-ol Attenuates Ulcerative Colitis via Targeting NLRP3 in Mice

Journal of agricultural and food chemistry, 2024-07, Vol.72 (30), p.16700-16707

2024

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3,5-Dimethyl-8-methoxy-3,4-dihydro-1 H -isochromen-6-ol Attenuates Ulcerative Colitis via Targeting NLRP3 in Mice

Journal of agricultural and food chemistry, 2024-07, Vol.72 (30), p.16700-16707

2024

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Biodistribution of arctigenin-loaded nanoparticles designed for multimodal imaging

Journal of nanobiotechnology, 2017-04, Vol.15 (1), p.27-10, Article 27

2017

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Anti-enterovirus 71 activity of native fucosylated chondroitin sulfates and their derivatives

Carbohydrate polymers, 2024-12, Vol.346, p.122657, Article 122657

2024

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Pollution characteristics, source appointment and environmental effect of oxygenated volatile organic compounds in Guangdong-Hong Kong-Macao Greater Bay Area: Implication for air quality management

The Science of the total environment, 2024-04, Vol.919, p.170836-170836, Article 170836

2024

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Inhibition of influenza a virus infection by natural stilbene piceatannol targeting virus hemagglutinin

Phytomedicine (Stuttgart), 2023-11, Vol.120, p.155058-155058, Article 155058

2023

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Evaluation and mechanistic analysis of the effect of the addition of alkaline earth metal CaO on Cd solidification enhancement in lightweight aggregate preparation

RSC advances, 2024-09, Vol.14 (41), p.30518-30528

2024

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Inhibitory effects and mechanisms of proanthocyanidins against enterovirus 71 infection

Virus research, 2023-05, Vol.329, p.199098-199098, Article 199098

2023

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A natural AKT inhibitor swertiamarin targets AKT‐PH domain, inhibits downstream signaling, and alleviates inflammation

The FEBS journal, 2020-05, Vol.287 (9), p.1816-1829

2020

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Ursolic Acid, a Natural Nutraceutical Agent, Targets Caspase3 and Alleviates Inflammation‐Associated Downstream Signal Transduction

Molecular nutrition & food research, 2017-12, Vol.61 (12), p.n/a

2017

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Ursolic acid alleviates tetrandrine-induced hepatotoxicity by competitively binding to the substrate-binding site of glutathione S-transferases

Phytomedicine (Stuttgart), 2022-09, Vol.104, p.154325, Article 154325

2022

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Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo

Phytomedicine (Stuttgart), 2022-08, Vol.103, p.154233-154233, Article 154233

2022

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The flavonoid baicalin improves glucose metabolism by targeting the PH domain of AKT and activating AKT/GSK3β phosphorylation

FEBS letters, 2019-01, Vol.593 (2), p.175-186

2019

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Design, synthesis, and biological evaluation of novel penindolone derivatives as potential inhibitors of hemagglutinin-mediated membrane fusion

European journal of medicinal chemistry, 2023-10, Vol.258, p.115615-115615, Article 115615

2023

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AKAP150 and its Palmitoylation Contributed to Pain Hypersensitivity Via Facilitating Synaptic Incorporation of GluA1-Containing AMPA Receptor in Spinal Dorsal Horn

Ligustilide covalently binds to Cys129 of HMGCS1 to ameliorate dyslipidemia

Atractylenolide-I covalently binds to CYP11B2, selectively inhibits aldosterone synthesis, and improves hyperaldosteronism

Qingfei Xiaoyan Wan,a traditional Chinese medicine formula, ameliorates Pseudomonas aeruginosa–induced acute lung inflammation by regulation of PI3K/AKT and Ras/MAPK pathways

The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism

Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics

Analyze and Identify Peiminine Target EGFR Improve Lung Function and Alleviate Pulmonary Fibrosis to Prevent Exacerbation of Chronic Obstructive Pulmonary Disease by Phosphoproteomics Analysis

Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells

Sign Learning Kink-based (SiLK) Quantum Monte Carlo for molecular systems

Micro-PET Imaging Demonstrates 3-O-β-D-Glucopyranosyl Platycodigenin as an Effective Metabolite Affects Permeability of Cell Membrane and Improves Dosimetry of [18F]-Phillygenin in Lung Tissue

Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins

3,5-Dimethyl-8-methoxy-3,4-dihydro‑1H‑isochromen-6-ol Attenuates Ulcerative Colitis via Targeting NLRP3 in Mice

3,5-Dimethyl-8-methoxy-3,4-dihydro-1 H -isochromen-6-ol Attenuates Ulcerative Colitis via Targeting NLRP3 in Mice

Biodistribution of arctigenin-loaded nanoparticles designed for multimodal imaging

Anti-enterovirus 71 activity of native fucosylated chondroitin sulfates and their derivatives

Pollution characteristics, source appointment and environmental effect of oxygenated volatile organic compounds in Guangdong-Hong Kong-Macao Greater Bay Area: Implication for air quality management

Inhibition of influenza a virus infection by natural stilbene piceatannol targeting virus hemagglutinin

Evaluation and mechanistic analysis of the effect of the addition of alkaline earth metal CaO on Cd solidification enhancement in lightweight aggregate preparation

Inhibitory effects and mechanisms of proanthocyanidins against enterovirus 71 infection

A natural AKT inhibitor swertiamarin targets AKT‐PH domain, inhibits downstream signaling, and alleviates inflammation

Ursolic Acid, a Natural Nutraceutical Agent, Targets Caspase3 and Alleviates Inflammation‐Associated Downstream Signal Transduction

Ursolic acid alleviates tetrandrine-induced hepatotoxicity by competitively binding to the substrate-binding site of glutathione S-transferases

Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo

The flavonoid baicalin improves glucose metabolism by targeting the PH domain of AKT and activating AKT/GSK3β phosphorylation

Design, synthesis, and biological evaluation of novel penindolone derivatives as potential inhibitors of hemagglutinin-mediated membrane fusion

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