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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids

Nature medicine, 2015-11, Vol.21 (11), p.1364-1371

2015

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Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids

Cell stem cell, 2021-06, Vol.28 (6), p.1090-1104.e6

2021

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Cell Polarity as a Regulator of Cancer Cell Behavior Plasticity

Annual review of cell and developmental biology, 2012-01, Vol.28 (1), p.599-625

2012

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Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion

Nature cell biology, 2013-02, Vol.15 (2), p.189-200

2013

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The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

Nature structural & molecular biology, 2012-02, Vol.19 (2), p.220-228

2012

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Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer

Breast cancer research : BCR, 2024-03, Vol.26 (1), p.56-56, Article 56

2024

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Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.163-168

2013

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Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Nature medicine, 2017-09, Vol.23 (9), p.1063-1071

2017

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Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

Current opinion in genetics & development, 2010-02, Vol.20 (1), p.41-50

2010

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Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2672-2688.e7

2019

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Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Cell, 2008-11, Vol.135 (5), p.865-878

2008

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Personalized RNA Medicine for Pancreatic Cancer

Clinical cancer research, 2018-04, Vol.24 (7), p.1734-1747

2018

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Methods (San Diego, Calif.), 2003-07, Vol.30 (3), p.256-268

2003

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Polarity proteins regulate mammalian cell–cell junctions and cancer pathogenesis

Current opinion in cell biology, 2009-10, Vol.21 (5), p.694-700

2009

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G-protein—coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4191-4196

2014

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Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement

Biophysical journal, 2016-04, Vol.110 (8), p.1886-1895

2016

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A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells

Genes & development, 2007-12, Vol.21 (24), p.3238-3243

2007

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HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Cancer cell, 2006-07, Vol.10 (1), p.25-38

2006

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Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo

PLoS biology, 2018-06, Vol.16 (6), p.e2004049-e2004049

2018

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Self-organization in cancer: Implications for histopathology, cancer cell biology, and metastasis

Cancer cell, 2021-04, Vol.39 (4), p.443-446

Muthuswamy, Senthil K.

2021

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Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'

Genes & development, 2011-07, Vol.25 (13), p.1412-1425

2011

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An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Nature cell biology, 2016-11, Vol.18 (11), p.1244-1252

2016

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Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT

Nature communications, 2023-02, Vol.14 (1), p.688-23, Article 688

2023

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The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

Cell, 2002-10, Vol.111 (1), p.29-40

2002

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The Signaling Adaptor Gab1 Regulates Cell Polarity by Acting as a PAR Protein Scaffold

Molecular cell, 2012-08, Vol.47 (3), p.469-483

2012

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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids

Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids

Cell Polarity as a Regulator of Cancer Cell Behavior Plasticity

Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer

Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Personalized RNA Medicine for Pancreatic Cancer

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Polarity proteins regulate mammalian cell–cell junctions and cancer pathogenesis

G-protein—coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion

Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement

A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo

Self-organization in cancer: Implications for histopathology, cancer cell biology, and metastasis

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

The Signaling Adaptor Gab1 Regulates Cell Polarity by Acting as a PAR Protein Scaffold

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