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The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8031

2021

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A specific proteinase 3 activity footprint in α1-antitrypsin deficiency

ERJ open research, 2019-08, Vol.5 (3)

2019

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Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

Science (American Association for the Advancement of Science), 1992-04, Vol.256 (5054), p.225-228

1992

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The Relationship of the Fibrinogen Cleavage Biomarker Aa-Val360 With Disease Severity and Activity in α1 -Antitrypsin Deficiency

Chest, 2015-08, Vol.148 (2), p.382-388

2015

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Comparative Assessment of the Ligand and Metal Ion Binding Properties of Integrins α9β1 and α4β1

Biochemistry (Easton), 2002-06, Vol.41 (22), p.7125-7141

2002

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A specific proteinase 3 activity footprint in α 1 -antitrypsin deficiency

ERJ open research, 2019-07, Vol.5 (3), p.95

2019

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So You Qualified Abroad: The Handbook for Overseas Medical Graduates in GP Training

Fry, Mandy

1st edition., 2014

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A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nature (London), 1992-04, Vol.356 (6372), p.768-774

1992

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Discovery of N-{N-[(3-Cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(l)-prolyl}-4-[(3′,5′-dichloroisonicotinoyl)amino]-(l)-phenylalanine (MK-0668), an Extremely Potent and Orally Active Antagonist of Very Late Antigen-4

Journal of medicinal chemistry, 2009-06, Vol.52 (11), p.3449-3452

2009

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Constraining the amide bond in N-Sulfonylated dipeptide VLA-4 antagonists

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1688-1691

2008

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Discovery of N-{ N-[(3-cyanobenzene) sulfonyl]-4( R)-(3,3-difluoropiperidin-1-yl)-( l)-prolyl}-4-[(3′,5′-dichloro-isonicotinoyl) amino]-( l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5803-5806

2009

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Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1173-1176

2010

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N-Aryl 2,6-Dimethoxybiphenylalanine Analogues as VLA-4 Antagonists

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (5), p.729-731

2002

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Characterization of α₄β₁ (CD49d/CD29) on equine leukocytes: Potential utility of a potent α₄β₁ (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction)

Veterinary immunology and immunopathology, 2009-07, Vol.130 (1-2), p.79-87

2009

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Characterization of alpha(4)beta(1) (CD49d/CD29) on equine leukocytes: potential utility of a potent alpha(4)beta(1) (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction)

Veterinary immunology and immunopathology, 2009-07, Vol.130 (1-2), p.79-87

2009

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Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (8), p.1997-2001

2005

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Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2331-2334

2004

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Influence of acid surrogates toward potency of VLA-4 antagonist

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (18), p.4053-4056

2005

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Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

Nature (London), 1986-05, Vol.321 (6065), p.75-79

1986

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Amidines as amide bond replacements in VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2323-2326

2004

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The Relationship of the Fibrinogen Cleavage Biomarker Aa-Val 360 With Disease Severity and Activity in α 1 -Antitrypsin Deficiency

Chest, 2015-08, Vol.148 (2), p.382-388

2015

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The fibrinogen cleavage product A alpha-Val(360), a specific marker of neutrophil elastase activity in vivo

Thorax, 2011, Vol.66 (8), p.686

2011

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Specific and dual antagonists of α4β1 and α4β7 integrins

Bioorganic & medicinal chemistry letters, 2002-01, Vol.12 (2), p.133-136

2002

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N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (11), p.1497-1500

2002

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N-Isonicotinoyl-( l)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (11), p.1891-1895

2003

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The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients

A specific proteinase 3 activity footprint in α1-antitrypsin deficiency

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

The Relationship of the Fibrinogen Cleavage Biomarker Aa-Val360 With Disease Severity and Activity in α1 -Antitrypsin Deficiency

Comparative Assessment of the Ligand and Metal Ion Binding Properties of Integrins α9β1 and α4β1

A specific proteinase 3 activity footprint in α 1 -antitrypsin deficiency

So You Qualified Abroad: The Handbook for Overseas Medical Graduates in GP Training

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Discovery of N-{N-[(3-Cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(l)-prolyl}-4-[(3′,5′-dichloroisonicotinoyl)amino]-(l)-phenylalanine (MK-0668), an Extremely Potent and Orally Active Antagonist of Very Late Antigen-4

Constraining the amide bond in N-Sulfonylated dipeptide VLA-4 antagonists

Discovery of N-{ N-[(3-cyanobenzene) sulfonyl]-4( R)-(3,3-difluoropiperidin-1-yl)-( l)-prolyl}-4-[(3′,5′-dichloro-isonicotinoyl) amino]-( l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist

Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists

N-Aryl 2,6-Dimethoxybiphenylalanine Analogues as VLA-4 Antagonists

Characterization of α₄β₁ (CD49d/CD29) on equine leukocytes: Potential utility of a potent α₄β₁ (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction)

Characterization of alpha(4)beta(1) (CD49d/CD29) on equine leukocytes: potential utility of a potent alpha(4)beta(1) (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction)

Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase

Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4

Influence of acid surrogates toward potency of VLA-4 antagonist

Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

Amidines as amide bond replacements in VLA-4 antagonists

The Relationship of the Fibrinogen Cleavage Biomarker Aa-Val 360 With Disease Severity and Activity in α 1 -Antitrypsin Deficiency

The fibrinogen cleavage product A alpha-Val(360), a specific marker of neutrophil elastase activity in vivo

Specific and dual antagonists of α4β1 and α4β7 integrins

N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

N-Isonicotinoyl-( l)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists

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