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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

Nature, 2007-07, Vol.448 (7152), p.439-444

2007

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Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.757-768

2012

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Advancing a clinically relevant perspective of the clonal nature of cancer

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.12054-12059

2011

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RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

Blood, 2011-04, Vol.117 (14), p.3847-3857

2011

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Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

Journal of translational medicine, 2009-06, Vol.7 (43), p.43-43, Article 43

2009

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RNAi microarray analysis in cultured mammalian cells

Genome research, 2003-10, Vol.13 (10), p.2341-2347

2003

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Functional evidence implicating S100P in prostate cancer progression

International journal of cancer, 2008-07, Vol.123 (2), p.330-339

2008

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Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

Nature genetics, 2004-09, Vol.36 (9), p.979-983

2004

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Comprehensive Copy Number and Gene Expression Profiling of the 17q23 Amplicon in Human Breast Cancer

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (10), p.5711-5716

2001

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RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

Molecular cancer, 2010-08, Vol.9 (1), p.218-218, Article 218

2010

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EphB2 Expression across 138 Human Tumor Types in a Tissue Microarray: High Levels of Expression in Gastrointestinal Cancers

Clinical cancer research, 2005-09, Vol.11 (18), p.6450-6458

2005

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PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation

British journal of haematology, 2008-02, Vol.140 (3), p.344-347

2008

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High-Resolution Analysis of Gene Copy Number Alterations in Human Prostate Cancer Using CGH on cDNA Microarrays: Impact of Copy Number on Gene Expression

Neoplasia (New York, N.Y.), 2004-05, Vol.6 (3), p.240-247

2004

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Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication

BMC cancer, 2010-05, Vol.10 (1), p.181-181, Article 181

2010

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Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling

Oncogene, 2001-10, Vol.20 (46), p.6718-6723

2001

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Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine

Human mutation, 2008-04, Vol.29 (4), p.461-467

2008

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Topoisomerase-IIα Is Upregulated in Malignant Peripheral Nerve Sheath Tumors and Associated With Clinical Outcome

Journal of clinical oncology, 2003-12, Vol.21 (24), p.4586-4591

2003

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Abstract PL05-01: Translational pharmacogenomics

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.PL05-01-PL05-01

Mousses, Spyro

2009

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Integration of genomic technologies for accelerated cancer drug development

BioTechniques, 2003-09, Vol.35 (3), p.580-593

2003

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Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities

Molecular cancer therapeutics, 2013-01, Vol.12 (1), p.104-116

2013

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Application of artificial intelligence to predict a new class of novel synthetic lethal targets

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.2598-2598

2019

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Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients

Spine (Philadelphia, Pa. 1976), 2019-06, Vol.44 (11), p.E640-E649

2019

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A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

Science translational medicine, 2021-07, Vol.13 (603)

2021

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Abstract 4081: Leveraging single-cell RNA sequencing data to design multi-targeting SeekRRNA therapeutics

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.4081-4081

2022

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Impact of DNA amplification on gene expression patterns in breast cancer

Cancer research (Chicago, Ill.), 2002-11, Vol.62 (21), p.6240-6245

2002

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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome

Advancing a clinically relevant perspective of the clonal nature of cancer

RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

RNAi microarray analysis in cultured mammalian cells

Functional evidence implicating S100P in prostate cancer progression

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

Comprehensive Copy Number and Gene Expression Profiling of the 17q23 Amplicon in Human Breast Cancer

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

EphB2 Expression across 138 Human Tumor Types in a Tissue Microarray: High Levels of Expression in Gastrointestinal Cancers

PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation

High-Resolution Analysis of Gene Copy Number Alterations in Human Prostate Cancer Using CGH on cDNA Microarrays: Impact of Copy Number on Gene Expression

Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication

Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling

Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine

Topoisomerase-IIα Is Upregulated in Malignant Peripheral Nerve Sheath Tumors and Associated With Clinical Outcome

Abstract PL05-01: Translational pharmacogenomics

Integration of genomic technologies for accelerated cancer drug development

Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities

Application of artificial intelligence to predict a new class of novel synthetic lethal targets

Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients

A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

Abstract 4081: Leveraging single-cell RNA sequencing data to design multi-targeting SeekRRNA therapeutics

Impact of DNA amplification on gene expression patterns in breast cancer

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