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Protein Engineering of the Archetypal Nitroarene Dioxygenase of Ralstonia sp. Strain U2 for Activity on Aminonitrotoluenes and Dinitrotoluenes through Alpha-Subunit Residues Leucine 225, Phenylalanine 350, and Glycine 407

Journal of Bacteriology, 2005-05, Vol.187 (10), p.3302-3310

2005

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Cytochrome P450 1A1 (CYP1A1) Inhibitor α-Naphthoflavone Interferes with UDP-Glucuronosyltransferase (UGT) Activity in Intact but Not in Permeabilized Hepatic Microsomes from 3-Methylcholanthrene-Treated Rats: Possible Involvement of UGT–P450 Interactions

Biological and Pharmaceutical Bulletin, 2004, Vol.27(1), pp.56-60

2004

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Oxidation of aminonitrotoluenes by 2,4-DNT dioxygenase of Burkholderia sp. strain DNT

Biotechnology and bioengineering, 2006-02, Vol.93 (2), p.231-237

2006

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Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli

Biochimica et biophysica acta, 2000-06, Vol.1475 (1), p.10-16

2000

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Interaction between Cytochrome P450 and Other Drug-Metabolizing Enzymes: Evidence for an Association of CYP1A1 with Microsomal Epoxide Hydrolase and UDP-Glucuronosyltransferase

Biochemical and biophysical research communications, 2000-07, Vol.273 (3), p.1048-1052

2000

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Cytosolic Acetyl Transfer and N-Deacetylation Associated with the Metabolism of Carcinogenic 2,4-Diaminotoluene in Rat Liver

Journal of health science (Tokyo, Japan), 2002-01, Vol.48 (6), p.485-492

2002

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Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substrate-specific activation of epoxide hydrolase function

Archives of biochemistry and biophysics, 2002-06, Vol.402 (2), p.275-280

2002

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AM1 calculation of hydration to aldehyde group in nitro-substituted benzaldehydes

International journal of quantum chemistry, 1993, Vol.45 (1), p.97-104

1993

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Secondary Metabolism of Dinitrobenzyl Glucuronide Related to Production of Genotoxic Compounds of Dinitrotoluene in Male Wistar Rat

Journal of health science (Tokyo, Japan), 2000, Vol.46 (5), p.329-335

2000

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Mutagenicities of 2,4- and 2,6-dinitrotoluenes and their reduced products in Salmonella typhimurium nitroreductase- and O-acetyltransferase-overproducing Ames test strains

Mutation research, 1998-12, Vol.420 (1), p.27-32

1998

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Synthesis of mutagenic 2,4-dinitro-[7-14C]benzaldehyde

Journal of labelled compounds & radiopharmaceuticals, 1994-07, Vol.34 (7), p.597-601

1994

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An Approach to the Patients with Cryopyrin-associated Periodic Syndrome (CAPS) : a New Biologic Response Modifier, Canakinumab

Nihon Rinshō Menʾeki Gakkai kaishi, 2012, Vol.35 (1), p.23-29

2012

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Comparison of mutagenicity and theoretical reactivity of 2,4-dinitrobenzaldehyde and 2,6-dinitrobenzaldehyde in bacterial mutation assay and molecular orbital method

Mutation research, 1990, Vol.243 (1), p.47-52

1990

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Reduction of 2,4-dinitrotoluene by Wistar rat liver microsomal and cytosol fractions

Toxicology and applied pharmacology, 1984-01, Vol.76 (1), p.105-112

1984

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Synthesis of Pyridinium Dinitrobenzyl Sulfates and Potassium (Dinitrobenzyl β-D-Glucopyranosid)Uronates

Chemical and Pharmaceutical Bulletin, 1998/01/15, Vol.46(1), pp.145-147

1998

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Metabolism of 2, 4-Dinitrotoluene, 2, 4-Dinitrobenzyl Alcohol and 2, 4-Dinitrobenzaldehyde by Rat Liver Microsomal and Cytosol Fractions

Chemical and Pharmaceutical Bulletin, 1987/04/25, Vol.35(4), pp.1579-1586

1987

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Responsiveness of parathyroid hormone to bone resorption in 13-day-old embryonic chick calvaria cultures

Journal of bone and mineral metabolism, 1994-08, Vol.12 (1), p.51-56

1994

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An Approach to the Patients with Cryopyrin-associated Periodic Syndrome (CAPS) : a New Biologic Response Modifier, Canakinumab

Japanese Journal of Clinical Immunology, 2012, Vol.35(1), pp.23-29

2012

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Metabolism of Dinitrotoluene Isomers by Escherichia coli Isolated from Human Intestine

Chemical and Pharmaceutical Bulletin, 1984/10/25, Vol.32(10), pp.4070-4075

1984

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Intestinal metabolism of mephentermine and its biliary metabolites in male Wistar rats

Xenobiotica, 1992, Vol.22 (6), p.701-708

1992

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Metabolism of 2,4-dinitrotoluene by Salmonella typhimurium strains TA98 TA98NR and TA98/1,8-DNP6, and mutagenicity of the metabolites of 2,4-dinitrotoluene and related compounds to strains TA98 and TA100

Mutation research, 1991-11, Vol.264 (3), p.147-153

1991

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Metabolism of Drugs. LXXII. Synthesis of Nalorphine-3- and -6-glucuronide and Identification of Urinary Metabolites of Nalorphine in Rabbits

Chemical and Pharmaceutical Bulletin, 1970/12/25, Vol.18(12), pp.2548-2554

1970

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Coronary arteritis of Kawasaki disease unresponsive to high-dose intravenous gammaglobulin successfully treated with plasmapheresis

Japanese Journal of Clinical Immunology, 1995/06/30, Vol.18(3), pp.282-288

1995

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Enterohepatic circulation of 2,4-dinitrobenzaldehyde, a mutagenic metabolite of 2,4-dinitrotoluene, in male Wistar rat

Xenobiotica, 1989, Vol.19 (1), p.83-92

1989

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Metabolism of 2, 4-Dinitrotoluene and 2, 6-Dinitrotoluene, and Their Dinitrobenzyl Alcohols and Dinitrobenzaldehydes by Wistar and Sprague-Dawley Rat Liver Microsomal and Cytosol Fractions

Chemical and Pharmaceutical Bulletin, 1989/07/25, Vol.37(7), pp.1904-1908

1989

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Protein Engineering of the Archetypal Nitroarene Dioxygenase of Ralstonia sp. Strain U2 for Activity on Aminonitrotoluenes and Dinitrotoluenes through Alpha-Subunit Residues Leucine 225, Phenylalanine 350, and Glycine 407

Cytochrome P450 1A1 (CYP1A1) Inhibitor α-Naphthoflavone Interferes with UDP-Glucuronosyltransferase (UGT) Activity in Intact but Not in Permeabilized Hepatic Microsomes from 3-Methylcholanthrene-Treated Rats: Possible Involvement of UGT–P450 Interactions

Oxidation of aminonitrotoluenes by 2,4-DNT dioxygenase of Burkholderia sp. strain DNT

Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli

Interaction between Cytochrome P450 and Other Drug-Metabolizing Enzymes: Evidence for an Association of CYP1A1 with Microsomal Epoxide Hydrolase and UDP-Glucuronosyltransferase

Cytosolic Acetyl Transfer and N-Deacetylation Associated with the Metabolism of Carcinogenic 2,4-Diaminotoluene in Rat Liver

Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substrate-specific activation of epoxide hydrolase function

AM1 calculation of hydration to aldehyde group in nitro-substituted benzaldehydes

Secondary Metabolism of Dinitrobenzyl Glucuronide Related to Production of Genotoxic Compounds of Dinitrotoluene in Male Wistar Rat

Mutagenicities of 2,4- and 2,6-dinitrotoluenes and their reduced products in Salmonella typhimurium nitroreductase- and O-acetyltransferase-overproducing Ames test strains

Synthesis of mutagenic 2,4-dinitro-[7-14C]benzaldehyde

An Approach to the Patients with Cryopyrin-associated Periodic Syndrome (CAPS) : a New Biologic Response Modifier, Canakinumab

Comparison of mutagenicity and theoretical reactivity of 2,4-dinitrobenzaldehyde and 2,6-dinitrobenzaldehyde in bacterial mutation assay and molecular orbital method

Reduction of 2,4-dinitrotoluene by Wistar rat liver microsomal and cytosol fractions

Synthesis of Pyridinium Dinitrobenzyl Sulfates and Potassium (Dinitrobenzyl β-D-Glucopyranosid)Uronates

Metabolism of 2, 4-Dinitrotoluene, 2, 4-Dinitrobenzyl Alcohol and 2, 4-Dinitrobenzaldehyde by Rat Liver Microsomal and Cytosol Fractions

Responsiveness of parathyroid hormone to bone resorption in 13-day-old embryonic chick calvaria cultures

An Approach to the Patients with Cryopyrin-associated Periodic Syndrome (CAPS) : a New Biologic Response Modifier, Canakinumab

Metabolism of Dinitrotoluene Isomers by Escherichia coli Isolated from Human Intestine

Intestinal metabolism of mephentermine and its biliary metabolites in male Wistar rats

Metabolism of 2,4-dinitrotoluene by Salmonella typhimurium strains TA98 TA98NR and TA98/1,8-DNP6, and mutagenicity of the metabolites of 2,4-dinitrotoluene and related compounds to strains TA98 and TA100

Metabolism of Drugs. LXXII. Synthesis of Nalorphine-3- and -6-glucuronide and Identification of Urinary Metabolites of Nalorphine in Rabbits

Coronary arteritis of Kawasaki disease unresponsive to high-dose intravenous gammaglobulin successfully treated with plasmapheresis

Enterohepatic circulation of 2,4-dinitrobenzaldehyde, a mutagenic metabolite of 2,4-dinitrotoluene, in male Wistar rat

Metabolism of 2, 4-Dinitrotoluene and 2, 6-Dinitrotoluene, and Their Dinitrobenzyl Alcohols and Dinitrobenzaldehydes by Wistar and Sprague-Dawley Rat Liver Microsomal and Cytosol Fractions

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