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Melanoma reactive TCR-modified T cells generated without activation retain a less differentiated phenotype and mediate a superior in vivo response

Scientific reports, 2021-06, Vol.11 (1), p.13327-13327, Article 13327

2021

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Improved MHC II epitope prediction - a step towards personalized medicine

Nature reviews. Clinical oncology, 2020-02, Vol.17 (2), p.71-72

2020

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NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

Molecular immunology, 2023-03, Vol.155, p.1-6

2023

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Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma

Melanoma research, 2018-06, Vol.28 (3), p.171-184

2018

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Protective effector memory CD4 T cells depend on ICOS for survival

PloS one, 2011-02, Vol.6 (2), p.e16529-e16529

2011

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NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses

Nature medicine, 2012-03, Vol.18 (3), p.422-428

2012

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ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection

PloS one, 2013-08, Vol.8 (8), p.e72955-e72955

2013

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HDAC inhibition prevents transgene expression downregulation and loss-of-function in T cell-receptor-transduced T cells

Molecular therapy. Oncolytics, 2021-03, Vol.20, p.352-363

2021

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Gata5 deficiency causes airway constrictor hyperresponsiveness in mice

American journal of respiratory cell and molecular biology, 2014-04, Vol.50 (4), p.787-795

2014

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Characterization of MHC class-I restricted TCRαβ+ CD4− CD8− double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

Cancer Immunology, Immunotherapy, 2009-05, Vol.58 (5), p.709-718

2009

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Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells

PloS one, 2009-11, Vol.4 (11), p.e7525-e7525

2009

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Characterization of MHC class-I restricted TCR alpha beta + CD4- CD8- double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

Cancer Immunology, Immunotherapy, 2009-05, Vol.58 (5), p.709-718

2009

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RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation

American journal of physiology. Lung cellular and molecular physiology, 2013-11, Vol.305 (10), p.L693-L701

2013

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Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L

American journal of respiratory cell and molecular biology, 2011-10, Vol.45 (4), p.843-850

2011

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ICOS Costimulation Expands Th2 Immunity by Augmenting Migration of Lymphocytes to Draining Lymph Nodes

The Journal of immunology (1950), 2008-07, Vol.181 (2), p.1019-1024

2008

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CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells

The Journal of immunology (1950), 2012-04, Vol.188 (8), p.3639-3647

2012

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Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression

Cancer Immunology, Immunotherapy, 2011-11, Vol.60 (11), p.1543-1551

2011

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Relationship between CD8-dependent antigen recognition, T cell functional avidity, and tumor cell recognition

Cancer Immunology, Immunotherapy, 2009-05, Vol.58 (5), p.719-728

2009

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Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+T cells and autoimmune vitiligo

Autoimmunity (Chur, Switzerland), 2011-12, Vol.44 (8), p.599-606

2011

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Fas ligand expression on T cells is sufficient to prevent prolonged airway inflammation in a murine model of asthma

American journal of respiratory cell and molecular biology, 2010-09, Vol.43 (3), p.342-348

2010

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CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo

Cellular immunology, 2009, Vol.259 (2), p.177-184

2009

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Utilizing IL-7 to generate melanoma antigen T cell receptor-modified cells for adoptive transfer in the absence of activation

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e14552-e14552

2017

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Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells

Cancer Immunology, Immunotherapy, 2018-02, Vol.67 (2), p.311-325

2018

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A new murine tumor model for studying HLA-A2-restricted anti-tumor immunity

Cancer letters, 2005-06, Vol.224 (1), p.153-166

2005

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ICOS protects against mortality from acute lung injury through activation of IL-5 + ILC2s

Mucosal immunology, 2018-01, Vol.11 (1), p.61-70

2018

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Melanoma reactive TCR-modified T cells generated without activation retain a less differentiated phenotype and mediate a superior in vivo response

Improved MHC II epitope prediction - a step towards personalized medicine

NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma

Protective effector memory CD4 T cells depend on ICOS for survival

NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses

ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection

HDAC inhibition prevents transgene expression downregulation and loss-of-function in T cell-receptor-transduced T cells

Gata5 deficiency causes airway constrictor hyperresponsiveness in mice

Characterization of MHC class-I restricted TCRαβ+ CD4− CD8− double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells

Characterization of MHC class-I restricted TCR alpha beta + CD4- CD8- double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation

Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L

ICOS Costimulation Expands Th2 Immunity by Augmenting Migration of Lymphocytes to Draining Lymph Nodes

CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells

Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression

Relationship between CD8-dependent antigen recognition, T cell functional avidity, and tumor cell recognition

Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+T cells and autoimmune vitiligo

Fas ligand expression on T cells is sufficient to prevent prolonged airway inflammation in a murine model of asthma

CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo

Utilizing IL-7 to generate melanoma antigen T cell receptor-modified cells for adoptive transfer in the absence of activation

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells

A new murine tumor model for studying HLA-A2-restricted anti-tumor immunity

ICOS protects against mortality from acute lung injury through activation of IL-5 + ILC2s

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