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CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

Nature reviews. Molecular cell biology, 2011-03, Vol.12 (3), p.141-151

2011

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CREB pathway links PGE2 signaling with macrophage polarization

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (51), p.15642-15647

2015

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Role of the cAMP Pathway in Glucose and Lipid Metabolism

Handbook of experimental pharmacology, 2016-01, Vol.233, p.29-49

2016

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14‐3‐3 proteins mediate inhibitory effects of cAMP on salt‐inducible kinases (SIKs)

The FEBS journal, 2018-02, Vol.285 (3), p.467-480

2018

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Transcriptional regulation by the phosphorylation-dependent factor CREB

Nature reviews. Molecular cell biology, 2001-08, Vol.2 (8), p.599-609

2001

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TRANSCRIPTIONAL REGULATION BY CYCLIC AMP

Annual review of biochemistry, 1997-01, Vol.66 (1), p.807-822

Montminy, Marc

1997

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Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (7), p.3087-3092

2010

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CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

Nature (London), 2009-07, Vol.460 (7254), p.534-537

2009

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Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

Nature (London), 2011-02, Vol.470 (7334), p.404-408

2011

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Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

Nature medicine, 2010-10, Vol.16 (10), p.1152-1156

2010

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Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Science (American Association for the Advancement of Science), 2005-12, Vol.310 (5754), p.1642-1646

2005

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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

Nature (London), 2008-11, Vol.456 (7219), p.269-273

2008

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CREB is activated by muscle injury and promotes muscle regeneration

PloS one, 2011-09, Vol.6 (9), p.e24714-e24714

2011

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Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes

Nature (London), 2012-04, Vol.485 (7396), p.128-132

2012

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Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways

Cell reports (Cambridge), 2021-05, Vol.35 (7), p.109136-109136, Article 109136

2021

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Hepatic Glucose Sensing via the CREB Coactivator CRTC2

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5868), p.1402-1405

2008

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CREB Is a Regulatory Target for the Protein Kinase Akt/PKB

The Journal of biological chemistry, 1998-12, Vol.273 (49), p.32377-32379

1998

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CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

Nature, 2005-10, Vol.437 (7062), p.1109-1114

2005

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Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4

Cell metabolism, 2014-06, Vol.19 (6), p.1058-1065

2014

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Genome-Wide Analysis of cAMP-Response Element Binding Protein Occupancy, Phosphorylation, and Target Gene Activation in Human Tissues

Proceedings of the National Academy of Sciences - PNAS, 2005-03, Vol.102 (12), p.4459-4464

2005

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mTOR links incretin signaling to HIF induction in pancreatic beta cells

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.16876-16882

2011

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The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114549-114549, Article 114549

2024

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Feedback Inhibition of CREB Signaling Promotes Beta Cell Dysfunction in Insulin Resistance

Cell reports (Cambridge), 2015-02, Vol.10 (7), p.1149-1157

2015

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The KLDpT activation loop motif is critical for MARK kinase activity

PloS one, 2019-12, Vol.14 (12), p.e0225727-e0225727

2019

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The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector

Cell, 2004-10, Vol.119 (1), p.61-74

2004

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CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

CREB pathway links PGE2 signaling with macrophage polarization

Role of the cAMP Pathway in Glucose and Lipid Metabolism

14‐3‐3 proteins mediate inhibitory effects of cAMP on salt‐inducible kinases (SIKs)

Transcriptional regulation by the phosphorylation-dependent factor CREB

TRANSCRIPTIONAL REGULATION BY CYCLIC AMP

Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity

CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

CREB is activated by muscle injury and promotes muscle regeneration

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes

Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways

Hepatic Glucose Sensing via the CREB Coactivator CRTC2

CREB Is a Regulatory Target for the Protein Kinase Akt/PKB

CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4

Genome-Wide Analysis of cAMP-Response Element Binding Protein Occupancy, Phosphorylation, and Target Gene Activation in Human Tissues

mTOR links incretin signaling to HIF induction in pancreatic beta cells

The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy

Feedback Inhibition of CREB Signaling Promotes Beta Cell Dysfunction in Insulin Resistance

The KLDpT activation loop motif is critical for MARK kinase activity

The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector

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