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T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC

Cellular immunology, 2002-05, Vol.217 (1), p.78-86

2002

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Neointimal Formation After Balloon-Induced Vascular Injury in Yucatan Minipigs is Reduced by Oral Rapamycin

Journal of cardiovascular pharmacology, 1999-06, Vol.33 (6), p.829-835

1999

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Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds

The Journal of biological chemistry, 2001-12, Vol.276 (51), p.48118-48126

2001

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Efficacies of ABT-773, a New Ketolide, against Experimental Bacterial Infections

Antimicrobial Agents and Chemotherapy, 2001-09, Vol.45 (9), p.2585-2593

2001

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New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models

Journal of medicinal chemistry, 2001-12, Vol.44 (25), p.4416-4430

2001

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3,5-Bis(trifluoromethyl)pyrazoles: A Novel Class of NFAT Transcription Factor Regulator

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.2975-2981

2000

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Identification of Receptor-Binding Residues in the Inflammatory Complement Protein C5a by Site-Directed Mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 1989-01, Vol.86 (1), p.292-296

1989

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32-Ascomycinyloxyacetic Acid Derived Immunosuppressants. Independence of Immunophilin Binding and Immunosuppressive Potency

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1764-1776

1998

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Synthesis and immunosuppressant activity of pyrazole carboxamides

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (19), p.2787-2792

1998

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Identification and synthesis of a receptor binding site of human anaphylatoxin C5a

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2068-2071

1991

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A Macrolactam Inhibitor of T Helper Type 1 and T Helper Type 2 Cytokine Biosynthesis for Topical Treatment of Inflammatory Skin Diseases

Journal of investigative dermatology, 1999-05, Vol.112 (5), p.729-738

1999

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Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4456-4461

1999

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Nephrotoxicity studies of the immunosuppressants tacrolimus (FK506) and ascomycin in rat models

Toxicology (Amsterdam), 1998-02, Vol.125 (2-3), p.169-181

1998

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Studies on an immunosuppressive macrolactam, ascomycin: Synthesis of a C-33 hydroxyl derivative

Bioorganic & medicinal chemistry letters, 1998-04, Vol.8 (8), p.935-938

1998

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Binding of Gc globulin (vitamin D binding protein) to C5a or C5a des Arg is not necessary for co-chemotactic activity

Journal of leukocyte biology, 1995-07, Vol.58 (1), p.55-58

1995

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Secondary Structure of Complement Component C3a Anaphylatoxin in Solution as Determined by NMR Spectroscopy: Differences between Crystal and Solution Conformations

Proceedings of the National Academy of Sciences - PNAS, 1988-07, Vol.85 (14), p.5036-5040

1988

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Structure-function studies in a series of carboxyl-terminal octapeptide analogs of anaphylatoxin C5a

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.220-223

1992

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Inhibition of p56(lck) tyrosine kinase by isothiazolones

Archives of biochemistry and biophysics, 1999-04, Vol.364 (1), p.19-29

1999

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Group B streptococci inactivate complement component C5a by enzymic cleavage at the C-terminus

Biochemical journal, 1991-02, Vol.273 (3), p.635-640

1991

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Tertiary structure of human complement component C5a in solution from nuclear magnetic resonance data

Biochemistry (Easton), 1989-01, Vol.28 (1), p.172-185

1989

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Improvements in the minimum binding sequence of C5a: examination of His-67

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.402-406

1992

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Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat

Transplantation proceedings, 1996-12, Vol.28 (6), p.3185-3188

1996

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Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues

FEBS letters, 1993-01, Vol.316 (2), p.107-113

1993

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Chemical Synthesis of a Gene Encoding the Human Complement Fragment C5a and Its Expression in Escherichia coli

Proceedings of the National Academy of Sciences - PNAS, 1985-06, Vol.82 (11), p.3543-3547

1985

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Comparison of FK-506, Rapamycin, Ascomycin, and Cyclosporine in Mouse Models of Host-versus-Graft Disease and Heterotopic Heart Transplantation

Annals of the New York Academy of Sciences, 1993-06, Vol.685 (1), p.55-57

1993

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T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC

Neointimal Formation After Balloon-Induced Vascular Injury in Yucatan Minipigs is Reduced by Oral Rapamycin

Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds

Efficacies of ABT-773, a New Ketolide, against Experimental Bacterial Infections

New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models

3,5-Bis(trifluoromethyl)pyrazoles: A Novel Class of NFAT Transcription Factor Regulator

Identification of Receptor-Binding Residues in the Inflammatory Complement Protein C5a by Site-Directed Mutagenesis

32-Ascomycinyloxyacetic Acid Derived Immunosuppressants. Independence of Immunophilin Binding and Immunosuppressive Potency

Synthesis and immunosuppressant activity of pyrazole carboxamides

Identification and synthesis of a receptor binding site of human anaphylatoxin C5a

A Macrolactam Inhibitor of T Helper Type 1 and T Helper Type 2 Cytokine Biosynthesis for Topical Treatment of Inflammatory Skin Diseases

Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12

Nephrotoxicity studies of the immunosuppressants tacrolimus (FK506) and ascomycin in rat models

Studies on an immunosuppressive macrolactam, ascomycin: Synthesis of a C-33 hydroxyl derivative

Binding of Gc globulin (vitamin D binding protein) to C5a or C5a des Arg is not necessary for co-chemotactic activity

Secondary Structure of Complement Component C3a Anaphylatoxin in Solution as Determined by NMR Spectroscopy: Differences between Crystal and Solution Conformations

Structure-function studies in a series of carboxyl-terminal octapeptide analogs of anaphylatoxin C5a

Inhibition of p56(lck) tyrosine kinase by isothiazolones

Group B streptococci inactivate complement component C5a by enzymic cleavage at the C-terminus

Tertiary structure of human complement component C5a in solution from nuclear magnetic resonance data

Improvements in the minimum binding sequence of C5a: examination of His-67

Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat

Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues

Chemical Synthesis of a Gene Encoding the Human Complement Fragment C5a and Its Expression in Escherichia coli

Comparison of FK-506, Rapamycin, Ascomycin, and Cyclosporine in Mouse Models of Host-versus-Graft Disease and Heterotopic Heart Transplantation

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