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New imide 5-HT1A receptor ligands - modification of terminal fragment geometry

Molecules (Basel, Switzerland), 2004-02, Vol.9 (3), p.170-177

2004

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Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands

Molecules (Basel, Switzerland), 2001-09, Vol.6 (9), p.784-795

2001

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On the Bioactive Conformation of NAN-190 (1) and MP3022 (2), 5-HT1A Receptor Antagonists

Journal of medicinal chemistry, 1999-12, Vol.42 (24), p.4952-4960

1999

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8-[4-[2-(1,2,3,4-Tetrahydroisoquinolinyl)]butyl]-8-azaspiro[4.5]decane-7,9-dione: A New 5-HT1A Receptor Ligand with the Same Activity Profile as Buspirone

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1125-1129

1996

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The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT1A/5-HT2A receptor activities of its 1-adamantoyloaminoalkyl derivatives

Bioorganic & medicinal chemistry, 2002, Vol.10 (1), p.87-95

2002

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Application of Similarity Matrices and Genetic Neural Networks in Quantitative Structure−Activity Relationships of 2- or 4-(4-Methylpiperazino)pyrimidines: 5-HT2A Receptor Antagonists

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.1901-1909

2000

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Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1229-1231

2001

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Stereoelectronic factors in the interaction with DNA of small aromatic molecules substituted with a short cationic chain: Importance of the polarity of the aromatic system of the molecule

Biochemistry (Easton), 1992-11, Vol.31 (44), p.10802-10808

1992

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Benzolactam Derivatives and Their Affinity for α1- and α2- Adrenoreceptors

Archiv der Pharmazie (Weinheim), 2001, Vol.334 (1), p.25-26

2001

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Addition and substitution reactions of chloropyrimidines with lithium reagents

Journal of organic chemistry, 1988-08, Vol.53 (17), p.4137-4140

1988

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Quantitative structure-activity relationship analysis of cation-substituted polyaromatic compounds as potentiators (amplifiers) of bleomycin-mediated degradation of DNA

Journal of medicinal chemistry, 1991-02, Vol.34 (2), p.580-588

1991

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Structure-Activity Relationship Studies of Central Nervous System Agents. 13.4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a New Putative 5-HT1A Receptor Antagonist, and Its Analogs

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2754-2760

1994

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Structure-activity relationship studies of central nervous system agents. 13. 4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a new putative 5-HT1A receptor antagonist, and its analogs

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2754-2760

1994

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Synthesis and stereochemistry of new trihydrodiazabicyclo-[3.m.n]alkano[4′,5′:1,2]pyrido[3,4-b]indole ring system

Journal of heterocyclic chemistry, 1993-12, Vol.30 (6), p.1543-1548

1993

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On the bioactive conformation of NAN-190 (1) and MP3022 (2), 5-HT(1A) receptor antagonists

Journal of medicinal chemistry, 1999-12, Vol.42 (24), p.4952-4960

1999

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Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (13), p.1819-1824

1999

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New 9- or 10-arylpiperazinoalkyl substituted pyrimido-or diazepino[2,1-f]purines with partial or full 5-HT1A agonistic activity

European journal of medicinal chemistry, 1999-02, Vol.34 (2), p.167-175

1999

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Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity

Polish journal of pharmacology, 2003-07, Vol.55 (4), p.543

2003

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Structure-activity relationship studies of CNS agents--XVII. Spiro[piperidine-4',1-(1,2,3,4-tetrahydro-beta-carboline)] as a probe defining the extended topographic model of 5-HT1A receptors

Bioorganic & medicinal chemistry, 1995-05, Vol.3 (5), p.533-538

1995

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Immunomodulating Action and Structure-Activity Relationships of Substituted Phenylamides of 5-Amino-3-methylisoxazole-4-carboxylic Acid

Archiv der Pharmazie (Weinheim), 1999-05, Vol.332 (5), p.158-162

1999

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The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives

Bioorganic & medicinal chemistry, 2002-01, Vol.10 (1), p.87-95

2002

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The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT 1A/5-HT 2A receptor activities of its 1-adamantoyloaminoalkyl derivatives

Bioorganic & medicinal chemistry, 2002, Vol.10 (1), p.87-95

2002

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3-(ω-Aminoalkyl)-5,5-dialkyl(or spirocycloalkyl-1′,5-)hydantoins as New 5-HT1A and 5-HT2A Receptor Ligands

Archiv der Pharmazie (Weinheim), 1996-06, Vol.329 (6), p.283-290

1996

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Application of Similarity Matrices and Genetic Neural Networks in Quantitative Structure−Activity Relationships of 2- or 4-(4-Methylpiperazino)pyrimidines: 5-HT 2A Receptor Antagonists

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.1901-1909

2000

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Influence of the Terminal Amide Fragment Geometry in Some 3-Arylideneindolin-2(1 H)-ones on Their 5-HT 1A/5-HT 2A Receptor Activity

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (9), p.1229-1231

2001

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New imide 5-HT1A receptor ligands - modification of terminal fragment geometry

Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands

On the Bioactive Conformation of NAN-190 (1) and MP3022 (2), 5-HT1A Receptor Antagonists

8-[4-[2-(1,2,3,4-Tetrahydroisoquinolinyl)]butyl]-8-azaspiro[4.5]decane-7,9-dione: A New 5-HT1A Receptor Ligand with the Same Activity Profile as Buspirone

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT1A/5-HT2A receptor activities of its 1-adamantoyloaminoalkyl derivatives

Application of Similarity Matrices and Genetic Neural Networks in Quantitative Structure−Activity Relationships of 2- or 4-(4-Methylpiperazino)pyrimidines: 5-HT2A Receptor Antagonists

Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity

Stereoelectronic factors in the interaction with DNA of small aromatic molecules substituted with a short cationic chain: Importance of the polarity of the aromatic system of the molecule

Benzolactam Derivatives and Their Affinity for α1- and α2- Adrenoreceptors

Addition and substitution reactions of chloropyrimidines with lithium reagents

Quantitative structure-activity relationship analysis of cation-substituted polyaromatic compounds as potentiators (amplifiers) of bleomycin-mediated degradation of DNA

Structure-Activity Relationship Studies of Central Nervous System Agents. 13.4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a New Putative 5-HT1A Receptor Antagonist, and Its Analogs

Structure-activity relationship studies of central nervous system agents. 13. 4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a new putative 5-HT1A receptor antagonist, and its analogs

Synthesis and stereochemistry of new trihydrodiazabicyclo-[3.m.n]alkano[4′,5′:1,2]pyrido[3,4-b]indole ring system

On the bioactive conformation of NAN-190 (1) and MP3022 (2), 5-HT(1A) receptor antagonists

Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides

New 9- or 10-arylpiperazinoalkyl substituted pyrimido-or diazepino[2,1-f]purines with partial or full 5-HT1A agonistic activity

Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity

Structure-activity relationship studies of CNS agents--XVII. Spiro[piperidine-4',1-(1,2,3,4-tetrahydro-beta-carboline)] as a probe defining the extended topographic model of 5-HT1A receptors

Immunomodulating Action and Structure-Activity Relationships of Substituted Phenylamides of 5-Amino-3-methylisoxazole-4-carboxylic Acid

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT 1A/5-HT 2A receptor activities of its 1-adamantoyloaminoalkyl derivatives

3-(ω-Aminoalkyl)-5,5-dialkyl(or spirocycloalkyl-1′,5-)hydantoins as New 5-HT1A and 5-HT2A Receptor Ligands

Application of Similarity Matrices and Genetic Neural Networks in Quantitative Structure−Activity Relationships of 2- or 4-(4-Methylpiperazino)pyrimidines: 5-HT 2A Receptor Antagonists

Influence of the Terminal Amide Fragment Geometry in Some 3-Arylideneindolin-2(1 H)-ones on Their 5-HT 1A/5-HT 2A Receptor Activity

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