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Identification in Haloferax volcanii of Phosphomevalonate Decarboxylase and Isopentenyl Phosphate Kinase as Catalysts of the Terminal Enzyme Reactions in an Archaeal Alternate Mevalonate Pathway

Journal of Bacteriology, 2014-03, Vol.196 (5), p.1055-1063

2014

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Phosphomevalonate Kinase: Functional Investigation of the Recombinant Human Enzyme

Biochemistry (Easton), 2006-03, Vol.45 (10), p.3235-3242

2006

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The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease

The Journal of biological chemistry, 2002-05, Vol.277 (20), p.18134-18142

2002

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Ribulose-1,5-Bisphosphate Carboxylase-Oxygenase

Annual review of biochemistry, 1983-01, Vol.52 (1), p.507-535

1983

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Functional Evaluation of Serine/Threonine Residues in the P-Loop of Rhodobacter sphaeroides Phosphoribulokinase

Biochemistry (Easton), 2001-12, Vol.40 (48), p.14530-14537

2001

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Staphylococcus aureus Mevalonate Kinase: Isolation and Characterization of an Enzyme of the Isoprenoid Biosynthetic Pathway

Journal of Bacteriology, 2004-01, Vol.186 (1), p.61-67

2004

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Investigation of the Functional Contributions of Invariant Serine Residues in Yeast Mevalonate Diphosphate Decarboxylase

Biochemistry (Easton), 2005-02, Vol.44 (7), p.2671-2677

2005

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3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity

The Journal of biological chemistry, 1994-07, Vol.269 (27), p.17841-17846

1994

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Abstracts, Division of Biological Chemistry, 219th National Meeting of the American Chemical Society, March 26−30, 2000

Biochemistry (Easton), 2000-02, Vol.39 (6), p.1542-1582

Miziorko, H. M

2000

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Identification of Catalytic Residues in Human Mevalonate Kinase

The Journal of biological chemistry, 1997-10, Vol.272 (41), p.25449-25454

1997

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Avian 3-hydroxy-3-methylglutaryl-CoA synthase. Characterization of a recombinant cholesterogenic isozyme and demonstration of the requirement for a sulfhydryl functionality in formation of the acetyl-enzyme reaction intermediate

The Journal of biological chemistry, 1993-06, Vol.268 (16), p.12129-12135

1993

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Investigation of conserved acidic residues in 3-hydroxy-3-methylglutaryl-CoA lyase: implications for human disease and for functional roles in a family of related proteins

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37092-37098

2003

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3-Hydroxy-3-methylglutaryl-CoA lyase is present in mouse and human liver peroxisomes

The Journal of biological chemistry, 1994-12, Vol.269 (50), p.31929-31932

1994

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The Influence of Conserved Aromatic Residues in 3-Hydroxy-3-methylglutaryl-CoA Synthase

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26443-26449

2003

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Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase: Characterization of the isolated recombinant protein and investigation of the enzyme's cation requirements

Biochemistry (Easton), 1992-11, Vol.31 (45), p.11224-11230

1992

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Investigation of invariant serine/threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site implicated in human inherited disease

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.12573

2001

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Expression in Haloferax volcanii of 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase Facilitates Isolation and Characterization of the Active Form of a Key Enzyme Required for Polyisoprenoid Cell Membrane Biosynthesis in Halophilic Archaea

Journal of Bacteriology, 2013-09, Vol.195 (17), p.3854-3862

2013

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3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency

The Journal of biological chemistry, 1993-02, Vol.268 (6), p.4376-4381

1993

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Avian 3‐hydroxy‐3‐methylglutaryl‐CoA lyase: Sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines

Protein science, 1992-09, Vol.1 (9), p.1144-1153

1992

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Affinity labeling of spinach leaf phosphoribulokinase by ATP analogs: modification of an active site lysine

The Journal of biological chemistry, 1990-03, Vol.265 (7), p.3642-3647

1990

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3-Hydroxy-3-methylglutaryl coenzyme A lyase: affinity labeling of the Pseudomonas mevalonii enzyme and assignment of cysteine-237 to the active site

Biochemistry (Easton), 1992-07, Vol.31 (29), p.6842-6847

1992

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Amino acid sequence of an active site peptide of avian liver mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase

The Journal of biological chemistry, 1985-11, Vol.260 (25), p.13513-13516

1985

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Identification and Functional Characterization of an Active-site Lysine in Mevalonate Kinase

The Journal of biological chemistry, 1997-02, Vol.272 (9), p.5741-5746

1997

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3-Hydroxy-3-methylglutaryl-CoA synthase. A role for glutamate 95 in general acid/base catalysis of C-C bond formation

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.17946

2000

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P mevalonii 3-Hydroxy-3-Methylglutaryl-CoA Lyase: Electron Paramagnetic Resonance Investigation of the Copper Binding Site

Archives of biochemistry and biophysics, 1994-08, Vol.312 (2), p.467-473

1994

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Identification in Haloferax volcanii of Phosphomevalonate Decarboxylase and Isopentenyl Phosphate Kinase as Catalysts of the Terminal Enzyme Reactions in an Archaeal Alternate Mevalonate Pathway

Phosphomevalonate Kinase: Functional Investigation of the Recombinant Human Enzyme

The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease

Ribulose-1,5-Bisphosphate Carboxylase-Oxygenase

Functional Evaluation of Serine/Threonine Residues in the P-Loop of Rhodobacter sphaeroides Phosphoribulokinase

Staphylococcus aureus Mevalonate Kinase: Isolation and Characterization of an Enzyme of the Isoprenoid Biosynthetic Pathway

Investigation of the Functional Contributions of Invariant Serine Residues in Yeast Mevalonate Diphosphate Decarboxylase

3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity

Abstracts, Division of Biological Chemistry, 219th National Meeting of the American Chemical Society, March 26−30, 2000

Identification of Catalytic Residues in Human Mevalonate Kinase

Avian 3-hydroxy-3-methylglutaryl-CoA synthase. Characterization of a recombinant cholesterogenic isozyme and demonstration of the requirement for a sulfhydryl functionality in formation of the acetyl-enzyme reaction intermediate

Investigation of conserved acidic residues in 3-hydroxy-3-methylglutaryl-CoA lyase: implications for human disease and for functional roles in a family of related proteins

3-Hydroxy-3-methylglutaryl-CoA lyase is present in mouse and human liver peroxisomes

The Influence of Conserved Aromatic Residues in 3-Hydroxy-3-methylglutaryl-CoA Synthase

Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase: Characterization of the isolated recombinant protein and investigation of the enzyme's cation requirements

Investigation of invariant serine/threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site implicated in human inherited disease

Expression in Haloferax volcanii of 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase Facilitates Isolation and Characterization of the Active Form of a Key Enzyme Required for Polyisoprenoid Cell Membrane Biosynthesis in Halophilic Archaea

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency

Avian 3‐hydroxy‐3‐methylglutaryl‐CoA lyase: Sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines

Affinity labeling of spinach leaf phosphoribulokinase by ATP analogs: modification of an active site lysine

3-Hydroxy-3-methylglutaryl coenzyme A lyase: affinity labeling of the Pseudomonas mevalonii enzyme and assignment of cysteine-237 to the active site

Amino acid sequence of an active site peptide of avian liver mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase

Identification and Functional Characterization of an Active-site Lysine in Mevalonate Kinase

3-Hydroxy-3-methylglutaryl-CoA synthase. A role for glutamate 95 in general acid/base catalysis of C-C bond formation

P mevalonii 3-Hydroxy-3-Methylglutaryl-CoA Lyase: Electron Paramagnetic Resonance Investigation of the Copper Binding Site

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