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Identification of the first highly selective inhibitor of human lactate dehydrogenase B

Scientific reports, 2021-11, Vol.11 (1), p.21353-21353, Article 21353

2021

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K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

Biochemical and biophysical research communications, 2017-03, Vol.484 (3), p.605-611

2017

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Discovery of artificial VIPR2-antagonist peptides possessing receptor- and ligand-selectivity

Biochemical and biophysical research communications, 2018-09, Vol.503 (3), p.1973-1979

2018

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A G Protein-coupled Receptor Responsive to Bile Acids

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9435-9440

2003

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Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology

Biochemistry and biophysics reports, 2017-09, Vol.11 (C), p.33-39

2017

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Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses

BMC cancer, 2012-11, Vol.12 (1), p.536-536, Article 536

2012

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The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Bioorganic & medicinal chemistry, 2000-07, Vol.8 (7), p.1697-1706

2000

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Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline

Biochemical and biophysical research communications, 2017-06, Vol.488 (2), p.393-399

2017

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Identification of α‑Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson’s Disease

ACS medicinal chemistry letters, 2022-09, Vol.13 (9), p.1421-1426

2022

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Crystal Structure of a Human K‑Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

ACS medicinal chemistry letters, 2017-07, Vol.8 (7), p.732-736

2017

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Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5759-5771

2017

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Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889

International journal of cancer, 2003-09, Vol.106 (5), p.799-805

2003

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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1795-1801

2011

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water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

Cancer chemotherapy and pharmacology, 2010, Vol.65 (2), p.363-371

2010

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Image analysis of dynamic drop test to measure the retention of hydrophobicity of polymeric insulating materials

2017 International Symposium on Electrical Insulating Materials (ISEIM), 2017, Vol.1, p.271-274

2017

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A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

Cancer chemotherapy and pharmacology, 2010, Vol.65 (5), p.363-371

2010

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Design and synthesis of novel prodrugs of 2′-deoxy-2′-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2241-2245

2007

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Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine

Cancer science, 1990-02, Vol.81 (2), p.188-195

1990

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Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.867-872

2003

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Determination of Curdlan in Foods by Using a Bacterial, .BETA.-1, 3-Glucanase Which Hydrolyze Resistant Curdlan with Formation of Laminaribiose

Nihon Shokuhin Kagaku Kōgaku kaishi, 1995, Vol.42 (11), p.913-919

1995

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The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase

Cancer research (Chicago, Ill.), 1998-03, Vol.58 (6), p.1165-1169

1998

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Comparative studies on the antitumor and immunosuppressive effects of the new fluorouracil derivative N4-trimethoxybenzoyl-5'-deoxy-5-fluorocytidine and its parent drug 5'-deoxy-5-fluorouridine

Chemical & pharmaceutical bulletin, 1990, Vol.38 (4), p.998-1003

1990

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High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine

Clinical cancer research, 1998-02, Vol.4 (2), p.493-497

1998

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ROLE OF URIDINE PHOSPHORYLASE FOR ANTITUMOR ACTIVITY OF 5'-DEOXY-5-FLUOROURIDINE

GANN Japanese Journal of Cancer Research, 1980/02/29, Vol.71(1), pp.112-123

1980

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Determination of Curdlan in Foods by Using a Bacterial β-1, 3-Glucanase Which Hydrolyze Resistant Curdlan with Formation of Laminaribiose

Nippon Shokuhin Kagaku Kogaku Kaishi, 1995/11/15, Vol.42(11), pp.913-919

1995

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Identification of the first highly selective inhibitor of human lactate dehydrogenase B

K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

Discovery of artificial VIPR2-antagonist peptides possessing receptor- and ligand-selectivity

A G Protein-coupled Receptor Responsive to Bile Acids

Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology

Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline

Identification of α‑Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson’s Disease

Crystal Structure of a Human K‑Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2

Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent

water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

Image analysis of dynamic drop test to measure the retention of hydrophobicity of polymeric insulating materials

A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

Design and synthesis of novel prodrugs of 2′-deoxy-2′-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues

Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine

Determination of Curdlan in Foods by Using a Bacterial, .BETA.-1, 3-Glucanase Which Hydrolyze Resistant Curdlan with Formation of Laminaribiose

The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase

Comparative studies on the antitumor and immunosuppressive effects of the new fluorouracil derivative N4-trimethoxybenzoyl-5'-deoxy-5-fluorocytidine and its parent drug 5'-deoxy-5-fluorouridine

High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine

ROLE OF URIDINE PHOSPHORYLASE FOR ANTITUMOR ACTIVITY OF 5'-DEOXY-5-FLUOROURIDINE

Determination of Curdlan in Foods by Using a Bacterial β-1, 3-Glucanase Which Hydrolyze Resistant Curdlan with Formation of Laminaribiose

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