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ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

PLoS biology, 2015-12, Vol.13 (12), p.e1002325-e1002325

2015

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Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

Cancer cell international, 2022-09, Vol.22 (1), p.1-286, Article 286

2022

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Cooperative Regulation of the Cell Division Cycle by the Protein Kinases RAF and AKT

Molecular and Cellular Biology, 2004-12, Vol.24 (24), p.10868-10881

2004

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Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

Atherosclerosis, 2011-06, Vol.216 (2), p.313-320

2011

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Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

mAbs, 2016-01, Vol.8 (2), p.389-404

2016

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Effects of the RAF MEK ERK and PI3K AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells

Oncogene, 2003-04, Vol.22 (16), p.2478-2492

2003

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XOMA 052, an anti‐IL‐1β monoclonal antibody, prevents IL‐1β‐mediated insulin resistance in 3T3‐L1 adipocytes

Obesity (Silver Spring, Md.), 2013-02, Vol.21 (2), p.306-309

2013

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Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

Oncotarget, 2016-06, Vol.7 (25), p.38164-38179

2016

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Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity

The Journal of biological chemistry, 2010-07, Vol.285 (27), p.20607-20614

2010

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P215 Filgotinib, a janus kinase 1 selective inhibitor, modulates disease-associated cytokines in patients with active RA

Rheumatology (Oxford, England), 2020-04, Vol.59 (Supplement_2)

2020

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O02 The JAK1-selective inhibitor filgotinib reverses the disease-associated transcriptional profile in the blood of patients with active rheumatoid arthritis

Rheumatology (Oxford, England), 2019-04, Vol.58 (Supplement_3)

2019

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Abstract 1768: An anti-TGF-β1/2 antibody that spares TGF-β3 retains full anti-tumor efficacy and generates an improved metabolic profile

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1768-1768

2018

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Abstract LB-306: Impacting Humoral Hypercalcemia of Malignancy (HHM) and associated PTH1R-mediated morbidities: Characterization of an anti-PTH1R antagonist monoclonal antibody to reverse hypercalcemia

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.LB-306-LB-306

2017

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ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-[Beta]-Induced Smad Activation: e1002325

PLoS biology, 2015-12, Vol.13 (12)

2015

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Risk of Periprosthetic Fractures with Direct Anterior Primary Total Hip Arthroplasty

The Journal of arthroplasty, 2016-10, Vol.31 (10), p.2295-2298

2016

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XOMA 052, an Anti-IL-1[Beta] Monoclonal Antibody, Prevents IL-1[Beta]-Mediated Insulin Resistance in 3T3-L1 Adipocytes

Obesity (Silver Spring, Md.), 2013-02, Vol.21 (2), p.306

2013

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Abstract B137: Inhibition of TGF-beta1 and 2 facilitates therapeutic tumor vaccine efficacy

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.B137-B137

2016

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Surgical fixation of extra-articular distal humerus fractures with a posterolateral plate through a triceps-reflecting technique

Journal of shoulder and elbow surgery, 2014-02, Vol.23 (2), p.251-257

2014

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Salvage Hip Arthroplasty After Failed Fixation of Proximal Femur Fractures

The Journal of arthroplasty, 2013-05, Vol.28 (5), p.855-859

2013

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Frequency and Treatment Trends for Periprosthetic Fractures About Total Hip Arthroplasty in the United States

The Journal of arthroplasty, 2016-09, Vol.31 (9), p.115-120

2016

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Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1b Activity

The Journal of biological chemistry, 2010-07, Vol.285 (27), p.20607-20614

2010

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HCD122, an Antagonist Human Anti-CD40 Monoclonal Antibody, Inhibits Tumor Growth in Xenograft Models of Human Diffuse Large B-Cell Lymphoma, a Subset of Non-Hodgkins Lymphoma

Blood, 2006-11, Vol.108 (11), p.2519-2519

2006

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Insulin-like growth factor binding protein-1 is elevated in patients with polycythemia vera and stimulates erythroid burst formation in vitro

Blood, 1997-03, Vol.89 (6), p.1862-1869

1997

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Increased Basal and Induced Tyrosine Phosphorylation of the Insulin-Like Growth Factor I Receptor β Subunit in Circulating Mononuclear Cells of Patients With Polycythemia Vera

Blood, 1995-08, Vol.86 (3), p.877-882

1995

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Increased basal and induced tyrosine phosphorylation of the insulin- like growth factor I receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera

Blood, 1995-08, Vol.86 (3), p.877-882

1995

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ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction

Cooperative Regulation of the Cell Division Cycle by the Protein Kinases RAF and AKT

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

Effects of the RAF MEK ERK and PI3K AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells

XOMA 052, an anti‐IL‐1β monoclonal antibody, prevents IL‐1β‐mediated insulin resistance in 3T3‐L1 adipocytes

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity

P215 Filgotinib, a janus kinase 1 selective inhibitor, modulates disease-associated cytokines in patients with active RA

O02 The JAK1-selective inhibitor filgotinib reverses the disease-associated transcriptional profile in the blood of patients with active rheumatoid arthritis

Abstract 1768: An anti-TGF-β1/2 antibody that spares TGF-β3 retains full anti-tumor efficacy and generates an improved metabolic profile

Abstract LB-306: Impacting Humoral Hypercalcemia of Malignancy (HHM) and associated PTH1R-mediated morbidities: Characterization of an anti-PTH1R antagonist monoclonal antibody to reverse hypercalcemia

ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-[Beta]-Induced Smad Activation: e1002325

Risk of Periprosthetic Fractures with Direct Anterior Primary Total Hip Arthroplasty

XOMA 052, an Anti-IL-1[Beta] Monoclonal Antibody, Prevents IL-1[Beta]-Mediated Insulin Resistance in 3T3-L1 Adipocytes

Abstract B137: Inhibition of TGF-beta1 and 2 facilitates therapeutic tumor vaccine efficacy

Surgical fixation of extra-articular distal humerus fractures with a posterolateral plate through a triceps-reflecting technique

Salvage Hip Arthroplasty After Failed Fixation of Proximal Femur Fractures

Frequency and Treatment Trends for Periprosthetic Fractures About Total Hip Arthroplasty in the United States

Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1b Activity

HCD122, an Antagonist Human Anti-CD40 Monoclonal Antibody, Inhibits Tumor Growth in Xenograft Models of Human Diffuse Large B-Cell Lymphoma, a Subset of Non-Hodgkins Lymphoma

Insulin-like growth factor binding protein-1 is elevated in patients with polycythemia vera and stimulates erythroid burst formation in vitro

Increased Basal and Induced Tyrosine Phosphorylation of the Insulin-Like Growth Factor I Receptor β Subunit in Circulating Mononuclear Cells of Patients With Polycythemia Vera

Increased basal and induced tyrosine phosphorylation of the insulin- like growth factor I receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera

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