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Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

The Lancet (British edition), 2015-05, Vol.385 (9982), p.2077-2087

2015

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Tenecteplase Thrombolysis for Acute Ischemic Stroke

Stroke (1970), 2020-11, Vol.51 (11), p.3440-3451

2020

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Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors

Circulation (New York, N.Y.), 2023-03, Vol.147 (13), p.1026-1038

2023

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Efficacy and Safety of a 4-Factor Prothrombin Complex Concentrate in Patients on Vitamin K Antagonists Presenting With Major Bleeding: A Randomized, Plasma-Controlled, Phase IIIb Study

Circulation (New York, N.Y.), 2013-09, Vol.128 (11), p.1234-1243

2013

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Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: The Third Sonography Outcomes Assessment Program (SOAP-3) Trial

Critical care medicine, 2005-08, Vol.33 (8), p.1764-1769

2005

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Preclinical and Clinical Data for Factor Xa and “Universal” Reversal Agents

The American journal of medicine, 2016-11, Vol.129 (11), p.S80-S88

2016

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Celebrating Annals of Emergency Medicine's 50th Anniversary

Annals of emergency medicine, 2022-01, Vol.79 (1), p.1-1

2022

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Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy

Stroke (1970), 2021-06, Vol.52 (6), p.2096-2105

2021

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Smartphone imaging repository: a novel method for creating a CT image bank

Trials, 2023-01, Vol.24 (1), p.46-46, Article 46

2023

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Exploring indications for the Use of direct oral anticoagulants and the associated risks of major bleeding

The American journal of managed care, 2017-04, Vol.23 (4 Suppl), p.S67-S80

2017

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Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for urgent vitamin K antagonist reversal

Transfusion (Philadelphia, Pa.), 2015-11, Vol.55 (11), p.2722-2729

2015

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Re-Initiation of Dabigatran and Direct Factor Xa Antagonists After a Major Bleed

The American journal of medicine, 2016-11, Vol.129 (11), p.S54-S63

2016

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Andexanet Response

Annals of emergency medicine, 2019-11, Vol.74 (5), p.724-725

2019

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Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel

Annals of emergency medicine, 2020-10, Vol.76 (4), p.470-485

2020

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Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients

Thrombosis and haemostasis, 2021-08, Vol.121 (8), p.1097

2021

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Preclinical and clinical data for factor Xa and “Universal” reversal agents

The American journal of emergency medicine, 2016-11, Vol.34 (11), p.39-45

2016

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Andexanet Alfa for Bleeding with Factor Xa Inhibitors. Reply

The New England journal of medicine, 2019-07, Vol.381 (2), p.192-193

2019

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Restart TICrH: An Adaptive Randomized Trial of Time Intervals to Restart Direct Oral Anticoagulants after Traumatic Intracranial Hemorrhage

Journal of neurotrauma, 2021-07, Vol.38 (13), p.1791

2021

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Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts

BMC neurology, 2022-06, Vol.22 (1), p.206-206, Article 206

2022

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Thromboembolic Events After Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-Controlled Studies

Annals of emergency medicine, 2016-01, Vol.67 (1), p.96-105.e5

2016

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Retrospective Analysis of the Real-World Utilization of 4-Factor Prothrombin Complex Concentrate and Plasma in Oral Anticoagulant-Associated Bleeding in US Hospitals

Clinical and applied thrombosis/hemostasis, 2023-01, Vol.29, p.10760296231179682-10760296231179682

2023

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Timing of anticoagulation after recent ischaemic stroke in patients with atrial fibrillation

Lancet neurology, 2019-01, Vol.18 (1), p.117-126

2019

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Re-Initiation of Dabigatran and Direct Factor Xa Antagonists after a Major Bleed

The American journal of emergency medicine, 2016-11, Vol.34 (11), p.19-25

2016

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Antifibrinolytic Therapy and Perioperative Considerations

Anesthesiology (Philadelphia), 2018-03, Vol.128 (3), p.657-670

2018

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Vitamin K Antagonist Reversal for Urgent Surgery Using 4-Factor Prothrombin Complex Concentrates: A Randomized Clinical Trial

JAMA network open, 2024-08, Vol.7 (8), p.e2424758

2024

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Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

Tenecteplase Thrombolysis for Acute Ischemic Stroke

Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors

Efficacy and Safety of a 4-Factor Prothrombin Complex Concentrate in Patients on Vitamin K Antagonists Presenting With Major Bleeding: A Randomized, Plasma-Controlled, Phase IIIb Study

Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: The Third Sonography Outcomes Assessment Program (SOAP-3) Trial

Preclinical and Clinical Data for Factor Xa and “Universal” Reversal Agents

Celebrating Annals of Emergency Medicine's 50th Anniversary

Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy

Smartphone imaging repository: a novel method for creating a CT image bank

Exploring indications for the Use of direct oral anticoagulants and the associated risks of major bleeding

Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for urgent vitamin K antagonist reversal

Re-Initiation of Dabigatran and Direct Factor Xa Antagonists After a Major Bleed

Andexanet Response

Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel

Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients

Preclinical and clinical data for factor Xa and “Universal” reversal agents

Andexanet Alfa for Bleeding with Factor Xa Inhibitors. Reply

Restart TICrH: An Adaptive Randomized Trial of Time Intervals to Restart Direct Oral Anticoagulants after Traumatic Intracranial Hemorrhage

Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts

Thromboembolic Events After Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-Controlled Studies

Retrospective Analysis of the Real-World Utilization of 4-Factor Prothrombin Complex Concentrate and Plasma in Oral Anticoagulant-Associated Bleeding in US Hospitals

Timing of anticoagulation after recent ischaemic stroke in patients with atrial fibrillation

Re-Initiation of Dabigatran and Direct Factor Xa Antagonists after a Major Bleed

Antifibrinolytic Therapy and Perioperative Considerations

Vitamin K Antagonist Reversal for Urgent Surgery Using 4-Factor Prothrombin Complex Concentrates: A Randomized Clinical Trial

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