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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

The Journal of clinical investigation, 2013-01, Vol.123 (1), p.340-347

2013

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A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor

Nature reviews. Cancer, 2015-05, Vol.15 (5), p.290-301

2015

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Neuregulin 1-erbB Signaling Is Necessary for Normal Myelination and Sensory Function

The Journal of neuroscience, 2006-03, Vol.26 (12), p.3079-3086

2006

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Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues

Cancer research (Chicago, Ill.), 2006-03, Vol.66 (5), p.2584-2591

2006

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Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis

Cancer cell, 2005, Vol.7 (1), p.65-75

2005

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Gene Expression Analysis Identifies Potential Biomarkers of Neurofibromatosis Type 1 Including Adrenomedullin

Clinical cancer research, 2010-10, Vol.16 (20), p.5048-5057

2010

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Oncolytic HSV and Erlotinib Inhibit Tumor Growth and Angiogenesis in a Novel Malignant Peripheral Nerve Sheath Tumor Xenograft Model

Molecular therapy, 2007-02, Vol.15 (2), p.279-286

2007

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Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

Clinical cancer research, 2012-09, Vol.18 (18), p.5020-5030

2012

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Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene

EMBO molecular medicine, 2009-07, Vol.1 (4), p.236-248

2009

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Brain Lipid Binding Protein in Axon-Schwann Cell Interactions and Peripheral Nerve Tumorigenesis

Molecular and Cellular Biology, 2003-03, Vol.23 (6), p.2213-2224

2003

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The N-terminal Region of Neuregulin Isoforms Determines the Accumulation of Cell Surface and Released Neuregulin Ectodomain

The Journal of biological chemistry, 2001-01, Vol.276 (4), p.2841-2851

2001

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MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1

Oncogene, 2014-12, Vol.33 (49), p.5626-5636

2014

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Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

Oncogene, 2010-01, Vol.29 (3), p.368-379

2010

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Oral 1821-3 - Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier

Nitric oxide, 2014-11, Vol.42, p.105-105

2014

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Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier

Nitric oxide, 2014-11, Vol.42, p.105

2014

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Model systems for neurofibroma and malignant peripheral nerve sheath tumor

Drug discovery today. Disease models, 2006, Vol.3 (2), p.175-182

2006

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A 1-Mb Physical Map and PAC Contig of the Imprinted Domain in 11p15.5 That Contains TAPA1 and the BWSCR1/WT2 Region

Genomics (San Diego, Calif.), 1997-08, Vol.43 (3), p.366-375

1997

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Novel Transcribed Sequences within the BWS/WT2 Region in 11p15.5: Tissue-Specific Expression Correlates with Cancer Type

Genomics (San Diego, Calif.), 1997-12, Vol.46 (3), p.355-363

1997

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Identification of candidate pediatric tumor suppressor genes on human chromosome 11P15.5

Crider-Miller, Shyra J

1998

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Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay

Cancer research (Chicago, Ill.), 1996-03, Vol.56 (6), p.1214-1218

1996

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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models

Journal for immunotherapy of cancer, 2023-10, Vol.11 (10), p.e007572

2023

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Neurofibromatosis 1 - Genetics
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Cell Line, Tumor
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Gene Expression Regulation, Neoplastic
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Genetics & Heredity
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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor

Neuregulin 1-erbB Signaling Is Necessary for Normal Myelination and Sensory Function

Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues

Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis

Gene Expression Analysis Identifies Potential Biomarkers of Neurofibromatosis Type 1 Including Adrenomedullin

Oncolytic HSV and Erlotinib Inhibit Tumor Growth and Angiogenesis in a Novel Malignant Peripheral Nerve Sheath Tumor Xenograft Model

Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene

Brain Lipid Binding Protein in Axon-Schwann Cell Interactions and Peripheral Nerve Tumorigenesis

The N-terminal Region of Neuregulin Isoforms Determines the Accumulation of Cell Surface and Released Neuregulin Ectodomain

MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

Oral 1821-3 - Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier

Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier

Model systems for neurofibroma and malignant peripheral nerve sheath tumor

A 1-Mb Physical Map and PAC Contig of the Imprinted Domain in 11p15.5 That Contains TAPA1 and the BWSCR1/WT2 Region

Novel Transcribed Sequences within the BWS/WT2 Region in 11p15.5: Tissue-Specific Expression Correlates with Cancer Type

Identification of candidate pediatric tumor suppressor genes on human chromosome 11P15.5

Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay

SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models

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