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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

British journal of cancer, 2008-10, Vol.99 (7), p.989-994

2008

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Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

Oncogene, 2013-03, Vol.32 (13), p.1638-1650

2013

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Metabolic modulation of glioblastoma with dichloroacetate

Science translational medicine, 2010-05, Vol.2 (31), p.31ra34

2010

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Soluble guanylate cyclase stimulators as a potential therapy for PAH: enthusiasm, pragmatism and concern

The European respiratory journal, 2009-04, Vol.33 (4), p.717-721

Michelakis, E D

2009

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2-Methoxyestradiol: A Hormonal Metabolite Modulates Stimulated T-Cells Function and proliferation

Transplantation proceedings, 2015-07, Vol.47 (6), p.2057-2066

2015

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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5

The FASEB journal, 2001-08, Vol.15 (10), p.1801-1803

2001

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O2 Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (14), p.7944-7949

1999

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Alterations in a redox oxygen sensing mechanism in chronic hypoxia

Journal of applied physiology (1985), 2001-06, Vol.90 (6), p.2249-2256

2001

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Impact of Myocardial Load on the Preservation of Donor Heart Function during Ex Vivo Perfusion

The Journal of heart and lung transplantation, 2016-04, Vol.35 (4), p.S186-S186

2016

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ANGIOGENESIS, MICRO-RNA AND RIGHT VENTRICLE FAILURE IN PULMONARY ARTERIAL HYPERTENSION

Canadian journal of cardiology, 2014-10, Vol.30 (10), p.S155-S156

2014

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nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (27), p.11418-11423

2007

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EX VIVO PERFUSION IN A LOADED STATE IMPROVES THE PRESERVATION OF DONOR HEART FUNCTION

Canadian journal of cardiology, 2015-10, Vol.31 (10), p.S202-S202

2015

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002 Mechanism of Hypoxia Induction of VWF

Canadian journal of cardiology, 2012-09, Vol.28 (5), p.S83-S84

2012

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Mitochondrial activation by inhibition of PDKII suppresses HIF1α signaling and angiogenesis in cancer

Oncogene, 2013-03, Vol.32 (13), p.1638

2013

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470 Hypoxia-induced pulmonary hypertension in mice modifies the expression pattern of von willebrand factor gene in lung endothelial cells

Canadian journal of cardiology, 2011-09, Vol.27 (5), p.S232-S233

2011

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Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension

Science translational medicine, 2010-08, Vol.2 (44), p.44ra58

2010

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Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation

Advances in experimental medicine and biology, 2000, Vol.475, p.219

2000

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352 Role of Mitochondrial Activity in the Development of Chronic Allograft Vasculopathy

The Journal of heart and lung transplantation, 2012-04, Vol.31 (4), p.S125-S125

2012

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626 Vascular Biology: Dichloroacetate Inhibits the Development of Intimal Hyperplasia, but Not Atherosclerotic Lesions

The Journal of heart and lung transplantation, 2012-04, Vol.31 (4), p.S216-S216

2012

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400 Metabolic Modulation – A Feasible Concept To Tackle Intimal Proliferation?

The Journal of heart and lung transplantation, 2011, Vol.30 (4), p.S137-S137

2011

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356 Pyruvate Dehydrogenase Kinase 2 Controls Vascular Remodeling

The Journal of heart and lung transplantation, 2012-04, Vol.31 (4), p.S126-S127

2012

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A Role for Potassium Channels in Smooth Muscle Cells and Platelets in the Etiology of Primary Pulmonary Hypertension

Chest, 1998-09, Vol.114 (3), p.200S-204S

1998

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Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: Comparison with inhaled nitric oxide

Circulation (New York, N.Y.), 2002-05, Vol.105 (20), p.2398-2403

2002

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Tadalafil Therapy for Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2009-06, Vol.119 (22), p.2894-2903

2009

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The Pleiotropic Effects of Oxygen-Derived Free-Radical Scavengers on the Graft During Normothermic Ex Situ Heart Perfusion

The Journal of heart and lung transplantation, 2022-04, Vol.41 (4), p.S97-S98

2022

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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

Metabolic modulation of glioblastoma with dichloroacetate

Soluble guanylate cyclase stimulators as a potential therapy for PAH: enthusiasm, pragmatism and concern

2-Methoxyestradiol: A Hormonal Metabolite Modulates Stimulated T-Cells Function and proliferation

Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5

O2 Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Alterations in a redox oxygen sensing mechanism in chronic hypoxia

Impact of Myocardial Load on the Preservation of Donor Heart Function during Ex Vivo Perfusion

ANGIOGENESIS, MICRO-RNA AND RIGHT VENTRICLE FAILURE IN PULMONARY ARTERIAL HYPERTENSION

nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

EX VIVO PERFUSION IN A LOADED STATE IMPROVES THE PRESERVATION OF DONOR HEART FUNCTION

002 Mechanism of Hypoxia Induction of VWF

Mitochondrial activation by inhibition of PDKII suppresses HIF1α signaling and angiogenesis in cancer

470 Hypoxia-induced pulmonary hypertension in mice modifies the expression pattern of von willebrand factor gene in lung endothelial cells

Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension

Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation

352 Role of Mitochondrial Activity in the Development of Chronic Allograft Vasculopathy

626 Vascular Biology: Dichloroacetate Inhibits the Development of Intimal Hyperplasia, but Not Atherosclerotic Lesions

400 Metabolic Modulation – A Feasible Concept To Tackle Intimal Proliferation?

356 Pyruvate Dehydrogenase Kinase 2 Controls Vascular Remodeling

A Role for Potassium Channels in Smooth Muscle Cells and Platelets in the Etiology of Primary Pulmonary Hypertension

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: Comparison with inhaled nitric oxide

Tadalafil Therapy for Pulmonary Arterial Hypertension

The Pleiotropic Effects of Oxygen-Derived Free-Radical Scavengers on the Graft During Normothermic Ex Situ Heart Perfusion

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