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Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring

Nature medicine, 2020-07, Vol.26 (7), p.1114-1124

2020

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Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma

Nature communications, 2021-10, Vol.12 (1), p.6023-6023, Article 6023

2021

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Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Cancer discovery, 2018-02, Vol.8 (2), p.196-215

2018

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Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: Relevance to atopic dermatitis

Journal of allergy and clinical immunology, 2011-06, Vol.127 (6), p.1522-1531.e8

2011

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EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma

Cancer discovery, 2015-03, Vol.5 (3), p.274-287

2015

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MITF Modulates Therapeutic Resistance through EGFR Signaling

Journal of investigative dermatology, 2015-07, Vol.135 (7), p.1863-1872

2015

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Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

Clinical cancer research, 2020-11, Vol.26 (22), p.6039-6050

2020

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Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (46), p.20126-20131

2010

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Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Molecular systems biology, 2019-03, Vol.15 (3), p.e8323-n/a

2019

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628 Circulatory plasma proteomic biomarkers combined with high-throughput proteomic screen of patient-derived organotypic tumor spheroids predict responses to immunotherapy in melanoma patients

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A717-A717

2023

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Targeting phospshatidylinositol 3-kinase signaling with novel phosphatidylinositol 3,4,5-triphosphate antagonists

Autophagy, 2011-06, Vol.7 (6), p.650-651

2011

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Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

Nature medicine, 2018-10, Vol.24 (10), p.1545-1549

2018

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A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Cell, 2018-11, Vol.175 (4), p.984-997.e24

2018

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Structural changes in squid (Loligo japonica) collagen after modification by formaldehyde

Journal of the science of food and agriculture, 2008-12, Vol.88 (15), p.2663-2668

2008

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Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, targeting CD4 in lymphocytes

Biochemical pharmacology, 2004-08, Vol.68 (4), p.641-649

2004

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A computational framework for studying neuron morphology from in vitro high content neuron-based screening

Journal of neuroscience methods, 2010-07, Vol.190 (2), p.299-309

2010

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Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer

Clinical cancer research, 2021-10, Vol.27 (20), p.5586-5594

2021

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Oligomannurarate sulfate, a novel antimitotic agent, exerts anti-cancer activity by binding to tubulin on novel site

Cancer biology & therapy, 2010-07, Vol.10 (1), p.89-98

2010

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Apo‐10′‐Lycopenoic acid Inhibits Cancer Cell Migration and Angiogenesis by Suppressing Lamellipodia Formation

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Apo-10’-lycopenoic acid inhibits cancer cell migration and angiogenesis and induces peroxisome proliferator-activated receptor γ

The Journal of nutritional biochemistry, 2018-06, Vol.56, p.26-34

2018

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A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF -mutated Melanoma to MAPK Inhibitors

Clinical cancer research, 2019-11, Vol.25 (22), p.6852-6867

2019

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Bioactive peptide isolated from casein phosphopeptides promotes calcium uptake in vitro and in vivo

Food & function, 2018-04, Vol.9 (4), p.2251-226

2018

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Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria

Molecular pharmacology, 2005-12, Vol.68 (6), p.1716-1727

2005

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Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring

Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Evolution of delayed resistance to immunotherapy in a melanoma responder

Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: Relevance to atopic dermatitis

EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma

MITF Modulates Therapeutic Resistance through EGFR Signaling

Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains

Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

628 Circulatory plasma proteomic biomarkers combined with high-throughput proteomic screen of patient-derived organotypic tumor spheroids predict responses to immunotherapy in melanoma patients

Targeting phospshatidylinositol 3-kinase signaling with novel phosphatidylinositol 3,4,5-triphosphate antagonists

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Structural changes in squid (Loligo japonica) collagen after modification by formaldehyde

Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, targeting CD4 in lymphocytes

A computational framework for studying neuron morphology from in vitro high content neuron-based screening

Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer

Oligomannurarate sulfate, a novel antimitotic agent, exerts anti-cancer activity by binding to tubulin on novel site

Apo‐10′‐Lycopenoic acid Inhibits Cancer Cell Migration and Angiogenesis by Suppressing Lamellipodia Formation

Apo-10’-lycopenoic acid inhibits cancer cell migration and angiogenesis and induces peroxisome proliferator-activated receptor γ

A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF -mutated Melanoma to MAPK Inhibitors

PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

Bioactive peptide isolated from casein phosphopeptides promotes calcium uptake in vitro and in vivo

Sulfated Polymannuroguluronate, a Novel Anti-AIDS Drug Candidate, Inhibits T Cell Apoptosis by Combating Oxidative Damage of Mitochondria

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