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Induction of drug metabolism: the role of nuclear receptors

Pharmacological reviews, 2003-12, Vol.55 (4), p.649-673

2003

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Pharmacogenetics and adverse drug reactions

The Lancet (British edition), 2000-11, Vol.356 (9242), p.1667-1671

Meyer, Urs A

2000

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Pregnane X Receptor Is a Target of Farnesoid X Receptor

The Journal of biological chemistry, 2006-07, Vol.281 (28), p.19081-19091

2006

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Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR

Archives of biochemistry and biophysics, 2005-01, Vol.433 (2), p.387-396

2005

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Regulatory Cross-Talk between Drug Metabolism and Lipid Homeostasis: Constitutive Androstane Receptor and Pregnane X Receptor Increase Insig-1 Expression

Molecular pharmacology, 2008-04, Vol.73 (4), p.1282-1289

2008

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Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

BMC genomics, 2009-08, Vol.10 (1), p.384-384, Article 384

2009

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NUBIScan, an in Silico Approach for Prediction of Nuclear Receptor Response Elements

Molecular endocrinology (Baltimore, Md.), 2002-06, Vol.16 (6), p.1269-1279

2002

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Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders

Alimentary Pharmacology & Therapeutics (Suppl), 2014-11, Vol.144 (2), p.134-161

2014

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In the Regulation of Cytochrome P450 Genes, Phenobarbital Targets LKB1 for Necessary Activation of AMP-Activated Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (3), p.1045-1050

2007

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A Regulatory Science Perspective on Warfarin Therapy: A Pharmacogenetic Opportunity

Journal of clinical pharmacology, 2009-02, Vol.49 (2), p.138-146

2009

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Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in Human and Mouse Liver

Molecular pharmacology, 2006-12, Vol.70 (6), p.1925-1934

2006

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Identification of the Xenosensors Regulating Human 5-Aminolevulinate Synthase

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (24), p.9127-9132

2004

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Molecular mechanisms of genetic polymorphisms of drug metabolism

Annual review of pharmacology and toxicology, 1997-01, Vol.37 (1), p.269-296

1997

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Pharmacogenetics - five decades of therapeutic lessons from genetic diversity

Nature reviews. Genetics, 2004-09, Vol.5 (9), p.669-676

Meyer, Urs A

2004

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Omics and Drug Response

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.475-502

2013

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Introduction to the Theme "Pharmacological Individuality: New Insights and Strategies for Personalized and Precise Drug Treatment"

Annual review of pharmacology and toxicology, 2024-01, Vol.64 (1), p.27-31

2024

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Regulation of human liver δ‐aminolevulinic acid synthase by bile acids

Hepatology (Baltimore, Md.), 2007-12, Vol.46 (6), p.1960-1970

2007

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Introduction to the Theme "Development of New Drugs: Moving from the Bench to Bedside and Improved Patient Care"

Annual review of pharmacology and toxicology, 2023-01, Vol.63 (1), p.15-18

2023

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Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor

Gastroenterology (New York, N.Y. 1943), 2002-06, Vol.122 (7), p.1954-1966

2002

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CXR, a Chicken Xenobiotic-Sensing Orphan Nuclear Receptor, Is Related to Both Mammalian Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR)

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10769-10774

2000

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Introduction to the Theme “New Insights, Strategies, and Therapeutics for Common Diseases”

Annual review of pharmacology and toxicology, 2022-01, Vol.62 (1), p.19-24

2022

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Introduction to the Theme “Ion Channels and Neuropharmacology: From the Past to the Future”

Annual review of pharmacology and toxicology, 2020-01, Vol.60 (1), p.1-6

2020

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Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1495-1501

2007

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Cytochrome P450 CYP1A1 Accumulates in the Cytosol of Kidney and Brain and Is Activated by Heme

Molecular pharmacology, 2002-11, Vol.62 (5), p.1061-1067

2002

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Introduction to the Theme “Old and New Toxicology: Interfaces with Pharmacology”

Annual review of pharmacology and toxicology, 2021-01, Vol.61 (1), p.1-7

2021

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Induction of drug metabolism: the role of nuclear receptors

Pharmacogenetics and adverse drug reactions

Pregnane X Receptor Is a Target of Farnesoid X Receptor

Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR

Regulatory Cross-Talk between Drug Metabolism and Lipid Homeostasis: Constitutive Androstane Receptor and Pregnane X Receptor Increase Insig-1 Expression

Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

NUBIScan, an in Silico Approach for Prediction of Nuclear Receptor Response Elements

Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders

In the Regulation of Cytochrome P450 Genes, Phenobarbital Targets LKB1 for Necessary Activation of AMP-Activated Protein Kinase

A Regulatory Science Perspective on Warfarin Therapy: A Pharmacogenetic Opportunity

Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in Human and Mouse Liver

Identification of the Xenosensors Regulating Human 5-Aminolevulinate Synthase

Molecular mechanisms of genetic polymorphisms of drug metabolism

Pharmacogenetics - five decades of therapeutic lessons from genetic diversity

Omics and Drug Response

Introduction to the Theme "Pharmacological Individuality: New Insights and Strategies for Personalized and Precise Drug Treatment"

Regulation of human liver δ‐aminolevulinic acid synthase by bile acids

Introduction to the Theme "Development of New Drugs: Moving from the Bench to Bedside and Improved Patient Care"

Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor

CXR, a Chicken Xenobiotic-Sensing Orphan Nuclear Receptor, Is Related to Both Mammalian Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR)

Introduction to the Theme “New Insights, Strategies, and Therapeutics for Common Diseases”

Introduction to the Theme “Ion Channels and Neuropharmacology: From the Past to the Future”

Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor

Cytochrome P450 CYP1A1 Accumulates in the Cytosol of Kidney and Brain and Is Activated by Heme

Introduction to the Theme “Old and New Toxicology: Interfaces with Pharmacology”

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