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Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

Frontiers in immunology, 2019-06, Vol.10, p.925-925

2019

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Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

Journal for immunotherapy of cancer, 2019-03, Vol.7 (1), p.85-85, Article 85

2019

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ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (23), p.6130-6141

2012

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Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

Cancer research (Chicago, Ill.), 2009-03, Vol.69 (5), p.2000-2009

2009

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Differences in Tumor Regulatory T-Cell Localization and Activation Status Impact Patient Outcome

Cancer research (Chicago, Ill.), 2009-10, Vol.69 (20), p.7895-7898

2009

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Second‐Generation CD73 Inhibitors Based on a 4,6‐Biaryl‐2‐thiopyridine Scaffold

ChemMedChem, 2023-04, Vol.18 (7), p.e202200594-n/a

2023

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Recruitment and Expansion of Tregs Cells in the Tumor Environment-How to Target Them?

Cancers, 2021-04, Vol.13 (8), p.1850

2021

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MDR1 in immunity: friend or foe?

Oncoimmunology, 2018-12, Vol.7 (12), p.e1499388-e1499388

2018

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Breast cancer‐derived transforming growth factor‐β and tumor necrosis factor‐α compromise interferon‐α production by tumor‐associated plasmacytoid dendritic cells

International journal of cancer, 2013-08, Vol.133 (3), p.771-778

2013

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A Milestone Review on How Macrophages Affect Tumor Growth

Cancer research (Chicago, Ill.), 2016-11, Vol.76 (22), p.6439-6442

2016

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Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+ regulatory T cells and are associated with poor prognosis in breast cancer patients

Oncoimmunology, 2013-01, Vol.2 (1), p.0-1

2013

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Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

Cancer research (Chicago, Ill.), 2012-10, Vol.72 (20), p.5188-5197

2012

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Autocrine Adenosine Regulates Tumor Polyfunctional CD73 + CD4 + Effector T Cells Devoid of Immune Checkpoints

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13), p.3604-3618

2018

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CD73 expression in normal and pathological human hepatobiliopancreatic tissues

Cancer Immunology, Immunotherapy, 2019-03, Vol.68 (3), p.467-478

2019

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Follicular B Lymphomas Generate Regulatory T Cells via the ICOS/ICOSL Pathway and Are Susceptible to Treatment by Anti-ICOS/ICOSL Therapy

Cancer research (Chicago, Ill.), 2016-08, Vol.76 (16), p.4648-4660

2016

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Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

Oncoimmunology, 2012-08, Vol.1 (5), p.759-761

2012

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Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

BMC cancer, 2011-05, Vol.11 (1), p.213-213, Article 213

2011

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IL‐6 as an intracrine growth factor for renal carcinoma cell lines

International journal of cancer, 2004-09, Vol.111 (5), p.653-661

2004

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4-Substituted-1,2,3-triazolo nucleotide analogues as CD73 inhibitors, their synthesis, in vitro screening, kinetic and in silico studies

Bioorganic chemistry, 2021-02, Vol.107, p.104577-104577, Article 104577

2021

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Targeting regulatory T cells

Targeted oncology, 2012-03, Vol.7 (1), p.15-28

2012

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Patients with metastatic breast cancer leading to CD4+ T cell lymphopaenia have poor outcome

European journal of cancer (1990), 2013-05, Vol.49 (7), p.1673-1682

2013

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ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+ T cells by plasmacytoid dendritic cells

Oncoimmunology, 2013-03, Vol.2 (3), p.e23185-e23185

2013

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Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells

Cancer research (Chicago, Ill.), 2011-10, Vol.71 (19), p.6143-6152

2011

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Long-lived immature dendritic cells mediated by TRANCE-RANK interaction

Blood, 2002-11, Vol.100 (10), p.3646-3655

2002

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Pembrolizumab in Lymphopenic Metastatic Breast Cancer Patients Treated with Metronomic Cyclophosphamide: A Clinical and Translational Prospective Study

Breast cancer targets and therapy, 2023-01, Vol.15, p.311-325

2023

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Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

Differences in Tumor Regulatory T-Cell Localization and Activation Status Impact Patient Outcome

Second‐Generation CD73 Inhibitors Based on a 4,6‐Biaryl‐2‐thiopyridine Scaffold

Recruitment and Expansion of Tregs Cells in the Tumor Environment-How to Target Them?

MDR1 in immunity: friend or foe?

Breast cancer‐derived transforming growth factor‐β and tumor necrosis factor‐α compromise interferon‐α production by tumor‐associated plasmacytoid dendritic cells

A Milestone Review on How Macrophages Affect Tumor Growth

Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+ regulatory T cells and are associated with poor prognosis in breast cancer patients

Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

Autocrine Adenosine Regulates Tumor Polyfunctional CD73 + CD4 + Effector T Cells Devoid of Immune Checkpoints

CD73 expression in normal and pathological human hepatobiliopancreatic tissues

Follicular B Lymphomas Generate Regulatory T Cells via the ICOS/ICOSL Pathway and Are Susceptible to Treatment by Anti-ICOS/ICOSL Therapy

Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

IL‐6 as an intracrine growth factor for renal carcinoma cell lines

4-Substituted-1,2,3-triazolo nucleotide analogues as CD73 inhibitors, their synthesis, in vitro screening, kinetic and in silico studies

Targeting regulatory T cells

Patients with metastatic breast cancer leading to CD4+ T cell lymphopaenia have poor outcome

ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+ T cells by plasmacytoid dendritic cells

Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells

Long-lived immature dendritic cells mediated by TRANCE-RANK interaction

Pembrolizumab in Lymphopenic Metastatic Breast Cancer Patients Treated with Metronomic Cyclophosphamide: A Clinical and Translational Prospective Study

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