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The hERG potassium channel and hERG screening for drug-induced torsades de pointes

Pharmacology & therapeutics (Oxford), 2008-08, Vol.119 (2), p.118-132

2008

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Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome

PLoS computational biology, 2011-12, Vol.7 (12), p.e1002313-e1002313

2011

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Disopyramide is an effective inhibitor of mutant HERG K + channels involved in variant 1 short QT syndrome

Journal of molecular and cellular cardiology, 2006-09, Vol.41 (3), p.563-566

2006

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Acidosis Impairs the Protective Role of hERG K+ Channels Against Premature Stimulation

Journal of cardiovascular electrophysiology, 2010-10, Vol.21 (10), p.1160-1169

2010

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Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome

Journal of molecular and cellular cardiology, 2009-11, Vol.47 (5), p.743-747

2009

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The N588K-HERG K + channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C

Biochemical and biophysical research communications, 2005-08, Vol.334 (2), p.441-449

2005

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Inhibition of the HERG K + channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656

FEBS letters, 2006-04, Vol.580 (8), p.1999-2005

2006

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Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide

European journal of pharmacology, 2002-01, Vol.435 (1), p.93-101

2002

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Short QT syndrome

Future cardiology, 2006-05, Vol.2 (3), p.293-301

2006

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The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C

Biochemical and biophysical research communications, 2005-08, Vol.334 (2), p.441

2005

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Development of TRPC Assays on Automated Electrophysiology Platforms

Biophysical journal, 2014-01, Vol.106 (2), p.753a-753a

2014

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Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome: e1002313

PLoS computational biology, 2011-12, Vol.7 (12)

2011

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The Short QT Syndrome

Heart Rate and Rhythm, p.517-538

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Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

PloS one, 2015-06, Vol.10 (6), p.e0131071-e0131071

2015

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The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

Assay and drug development technologies, 2014-06, Vol.12 (5), p.282

2014

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Erg1 Potassium Channel
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Qt Interval
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Short Qt Syndrome
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Ether-A-Go-Go Potassium Channels - Antagonists & Inhibitors
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The hERG potassium channel and hERG screening for drug-induced torsades de pointes

Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome

Disopyramide is an effective inhibitor of mutant HERG K + channels involved in variant 1 short QT syndrome

Acidosis Impairs the Protective Role of hERG K+ Channels Against Premature Stimulation

Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome

The N588K-HERG K + channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C

Inhibition of the HERG K + channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656

Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide

Short QT syndrome

The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C

Development of TRPC Assays on Automated Electrophysiology Platforms

Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome: e1002313

The Short QT Syndrome

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

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