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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

American journal of physiology. Lung cellular and molecular physiology, 2009-12, Vol.297 (6), p.L1013-L1032

2009

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Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2010-06, Vol.121 (25), p.2747-2754

2010

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Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia

The Journal of pharmacology and experimental therapeutics, 2021-05, Vol.377 (2), p.284

2021

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MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension

American journal of physiology. Heart and circulatory physiology, 2016-09, Vol.311 (3), p.H689-H698

2016

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Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

Journal of controlled release, 2015-07, Vol.210, p.67-75

2015

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Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2015-02, Vol.308 (3), p.L287-L300

2015

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Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Journal of the American College of Cardiology, 2009-06, Vol.54 (1), p.S20-S31

2009

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Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension

Journal of controlled release, 2013-04, Vol.167 (2), p.189-199

2013

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Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

Hypertension (Dallas, Tex. 1979), 2014-12, Vol.64 (6), p.1266-1274

2014

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Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling

American journal of physiology. Lung cellular and molecular physiology, 2019-01, Vol.316 (1), p.L119-L130

2019

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Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats

Circulation research, 2007-03, Vol.100 (6), p.923-929

2007

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Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation

American journal of physiology. Lung cellular and molecular physiology, 2020-04, Vol.318 (4), p.L773-L786

2020

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Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats

American journal of physiology. Heart and circulatory physiology, 2014-01, Vol.306 (2), p.H243-H250

2014

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Aneurysm-type plexiform lesions form in supernumerary arteries in pulmonary arterial hypertension: potential therapeutic implications

American journal of physiology. Lung cellular and molecular physiology, 2019-12, Vol.317 (6), p.L805-L815

2019

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How does pulmonary endarterectomy cure CTEPH: A clue to cure PAH?

American journal of physiology. Lung cellular and molecular physiology, 2016-10, Vol.311 (4), p.L766-L769

2016

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TRPC4 Inactivation Confers a Survival Benefit in Severe Pulmonary Arterial Hypertension

The American journal of pathology, 2013-12, Vol.183 (6), p.1779-1788

2013

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Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase

American journal of physiology. Lung cellular and molecular physiology, 2004-10, Vol.287 (4), p.L656-L664

2004

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Myoendothelial gap junctional signaling induces differentiation of pulmonary arterial smooth muscle cells

American journal of physiology. Lung cellular and molecular physiology, 2011-10, Vol.301 (4), p.L527-L535

2011

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Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling

American journal of physiology. Lung cellular and molecular physiology, 2007-04, Vol.292 (4), p.L885-L897

2007

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Rho kinase-mediated vasoconstriction in pulmonary hypertension

Advances in experimental medicine and biology, 2010-01, Vol.661, p.299

2010

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Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone

American journal of physiology. Lung cellular and molecular physiology, 2008-07, Vol.295 (1), p.L71-L78

2008

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Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat

Journal of applied physiology (1985), 2006-03, Vol.100 (3), p.996-1002

2006

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Fifty Years of Monocrotaline-Induced Pulmonary Hypertension: What Has It Meant to the Field?

Chest, 2017-12, Vol.152 (6), p.1106-1108

2017

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Role of endothelin-1 in lung disease

Respiratory research, 2001-01, Vol.2 (2), p.90-101

2001

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Haemodynamic unloading reverses occlusive vascular lesions in severe pulmonary hypertension

Cardiovascular research, 2016-07, Vol.111 (1), p.16-25

2016

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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension

Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia

MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension

Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling

Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats

Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation

Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats

Aneurysm-type plexiform lesions form in supernumerary arteries in pulmonary arterial hypertension: potential therapeutic implications

How does pulmonary endarterectomy cure CTEPH: A clue to cure PAH?

TRPC4 Inactivation Confers a Survival Benefit in Severe Pulmonary Arterial Hypertension

Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase

Myoendothelial gap junctional signaling induces differentiation of pulmonary arterial smooth muscle cells

Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling

Rho kinase-mediated vasoconstriction in pulmonary hypertension

Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat

Fifty Years of Monocrotaline-Induced Pulmonary Hypertension: What Has It Meant to the Field?

Role of endothelin-1 in lung disease

Haemodynamic unloading reverses occlusive vascular lesions in severe pulmonary hypertension

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