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Cysteine proteases of parasitic organisms

Molecular & Biochemical Parasitology, 2002-03, Vol.120 (1), p.1-21

2002

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A Cysteine Protease Inhibitor Protects Dogs from Cardiac Damage during Infection by Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy, 2005-12, Vol.49 (12), p.5160-5161

2005

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Two Approaches to Discovering and Developing New Drugs for Chagas Disease

Memórias do Instituto Oswaldo Cruz, 2009-07, Vol.104 (s1), p.263-269

2009

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Synthetic and natural protease inhibitors provide insights into parasite development, virulence and pathogenesis

Current medicinal chemistry, 2013-08, Vol.20 (25), p.3078-3102

2013

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Modulation of Blood Fluke Development in the Liver by Hepatic CD4+Lymphocytes

Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5545), p.1358-1361

2001

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Leishmania tropica: cysteine proteases are essential for growth and pathogenicity

Experimental parasitology, 2004-03, Vol.106 (3), p.158-163

2004

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Structure-Based Inhibitor Design by Using Protein Models for the Development of Antiparasitic Agents

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (8), p.3583-3587

1993

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Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens)

Infection and Immunity, 1997-02, Vol.65 (2), p.767-773

1997

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Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Journal of medicinal chemistry, 2002-06, Vol.45 (13), p.2695-2707

2002

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Identification, Cloning, and Recombinant Expression of Procalin, a Major Triatomine Allergen

The Journal of immunology (1950), 2001-09, Vol.167 (5), p.2694-2699

2001

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Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice

Nature (London), 1992-04, Vol.356 (6370), p.604-607

1992

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A functional proteomics screen of proteases in colorectal carcinoma

Molecular medicine (Cambridge, Mass.), 2000-05, Vol.6 (5), p.450-460

2000

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The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi

The Journal of biological chemistry, 1992-04, Vol.267 (11), p.7411-7420

1992

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Anisakiasis

Clinical Microbiology Reviews, 1989-07, Vol.2 (3), p.278-284

1989

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Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action

International journal for parasitology, 1999-06, Vol.29 (6), p.833-837

1999

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

The Journal of experimental medicine, 1998-08, Vol.188 (4), p.725-734

1998

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Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei

Molecular medicine (Cambridge, Mass.), 2000-08, Vol.6 (8), p.660-669

2000

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Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus

The Journal of biological chemistry, 1992-08, Vol.267 (24), p.17339-17346

1992

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Intercellular adhesion molecule 1 is the major adhesion molecule expressed during schistosome granuloma formation

Infection and Immunity, 1996-11, Vol.64 (11), p.4706-4713

1996

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Cysteine protease inhibitors as chemotherapy for parasitic infections

Bioorganic & medicinal chemistry, 1999-04, Vol.7 (4), p.639-644

1999

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Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6115-6118

1993

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Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases

Journal of the American Chemical Society, 1998-10, Vol.120 (42), p.10994-10995

1998

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Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon γ knockout mice

The Journal of experimental medicine, 1994-07, Vol.180 (1), p.43-51

1994

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Cytokine induction and exploitation in schistosome infections

Parasitology, 1997-01, Vol.115 (7), p.107-112

McKERROW, J. H.

1997

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Thiol proteinase expression and pathogenicity of Entamoeba histolytica

Journal of Clinical Microbiology, 1989-12, Vol.27 (12), p.2772-2777

1989

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Cysteine proteases of parasitic organisms

A Cysteine Protease Inhibitor Protects Dogs from Cardiac Damage during Infection by Trypanosoma cruzi

Two Approaches to Discovering and Developing New Drugs for Chagas Disease

Synthetic and natural protease inhibitors provide insights into parasite development, virulence and pathogenesis

Modulation of Blood Fluke Development in the Liver by Hepatic CD4+Lymphocytes

Leishmania tropica: cysteine proteases are essential for growth and pathogenicity

Structure-Based Inhibitor Design by Using Protein Models for the Development of Antiparasitic Agents

Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens)

Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Identification, Cloning, and Recombinant Expression of Procalin, a Major Triatomine Allergen

Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice

A functional proteomics screen of proteases in colorectal carcinoma

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi

Anisakiasis

Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei

Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus

Intercellular adhesion molecule 1 is the major adhesion molecule expressed during schistosome granuloma formation

Cysteine protease inhibitors as chemotherapy for parasitic infections

Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases

Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon γ knockout mice

Cytokine induction and exploitation in schistosome infections

Thiol proteinase expression and pathogenicity of Entamoeba histolytica

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