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Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed

Journal of structural biology, 2015-12, Vol.192 (3), p.539-544

2015

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Randomized Phase III Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the Vascular Disrupting Agent Vadimezan (ASA404) in Advanced Non–Small-Cell Lung Cancer

Journal of clinical oncology, 2011-08, Vol.29 (22), p.2965-2971

2011

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Membrane transporters as determinants of the pharmacology of platinum anticancer drugs

Current cancer drug targets, 2012-10, Vol.12 (8), p.962

2012

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Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons

The Journal of pharmacology and experimental therapeutics, 2011-08, Vol.338 (2), p.537

2011

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Predicting effects on oxaliplatin clearance: in vitro, kinetic and clinical studies of calcium- and magnesium-mediated oxaliplatin degradation

Scientific reports, 2017-06, Vol.7 (1), p.4073-11, Article 4073

2017

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A phase I trial of PR-104, a pre-prodrug of the bioreductive prodrug PR-104A, given weekly to solid tumour patients

BMC cancer, 2011-10, Vol.11 (1), p.432-432, Article 432

2011

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PR-104 a bioreductive pre-prodrug combined with gemcitabine or docetaxel in a phase Ib study of patients with advanced solid tumours

BMC cancer, 2012-10, Vol.12 (1), p.496-496, Article 496

2012

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Phase I drug-interaction study of effects of calcium and magnesium infusions on oxaliplatin pharmacokinetics and acute neurotoxicity in colorectal cancer patients

BMC cancer, 2013-10, Vol.13 (1), p.495-495, Article 495

2013

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Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability

BMC cancer, 2010-08, Vol.10 (1), p.451-451, Article 451

2010

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Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons

Biochemical pharmacology, 2013-01, Vol.85 (2), p.207-215

2013

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The Effects of Synthetically Modified Natural Compounds on ABC Transporters

Pharmaceutics, 2018-08, Vol.10 (3), p.127

2018

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Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test

Oncotarget, 2017-11, Vol.8 (60), p.101437-101451

2017

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5,6-Dimethylxanthenone-4-Acetic Acid in the Treatment of Refractory Tumors: a Phase I Safety Study of a Vascular Disrupting Agent

Clinical cancer research, 2006-03, Vol.12 (6), p.1776-1784

2006

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Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer

Cancer, 2010-04, Vol.116 (8), p.1859-1871

2010

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Differential Expression of ATP7A, ATP7B and CTR1 in Adult Rat Dorsal Root Ganglion Tissue

Molecular pain, 2010-09, Vol.6 (1), p.53-53

2010

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Muscle ultrasound in the assessment of oxaliplatin-induced neurotoxicity

Clinical neurophysiology, 2020-01, Vol.131 (1), p.343-344

2020

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New-generation platinum drugs in the treatment of cisplatin-resistant cancers

Expert opinion on investigational drugs, 2005-08, Vol.14 (8), p.1033-1046

McKeage, Mark J

2005

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Hormone Resistance in Two MCF-7 Breast Cancer Cell Lines is Associated with Reduced mTOR Signaling, Decreased Glycolysis, and Increased Sensitivity to Cytotoxic Drugs

Frontiers in oncology, 2014-01, Vol.4, p.221-221

2014

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Role of platinum DNA damage‐induced transcriptional inhibition in chemotherapy‐induced neuronal atrophy and peripheral neurotoxicity

Journal of neurochemistry, 2015-12, Vol.135 (6), p.1099-1112

2015

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Oxaliplatin-Induced Loss of Phosphorylated Heavy Neurofilament Subunit Neuronal Immunoreactivity in Rat Drg Tissue

Molecular pain, 2009-11, Vol.5 (1), p.66-66

2009

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Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-06, Vol.837 (1), p.29-34

2006

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Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity

Journal of inorganic biochemistry, 2017-12, Vol.177, p.249-258

2017

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Phase IB Trial of the Anti-Cancer Stem Cell DLL4-Binding Agent Demcizumab with Pemetrexed and Carboplatin as First-Line Treatment of Metastatic Non-Squamous NSCLC

Targeted oncology, 2018-02, Vol.13 (1), p.89-98

2018

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Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

Coordination chemistry reviews, 2002-10, Vol.232 (1), p.127-135

2002

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Incomplete uptake of EGFR mutation testing and its impact on estimation of mutation prevalence in patients with non-squamous NSCLC: A population-based study in New Zealand

Cancer epidemiology, 2018-12, Vol.57, p.24-32

2018

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Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed

Randomized Phase III Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the Vascular Disrupting Agent Vadimezan (ASA404) in Advanced Non–Small-Cell Lung Cancer

Membrane transporters as determinants of the pharmacology of platinum anticancer drugs

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons

Predicting effects on oxaliplatin clearance: in vitro, kinetic and clinical studies of calcium- and magnesium-mediated oxaliplatin degradation

A phase I trial of PR-104, a pre-prodrug of the bioreductive prodrug PR-104A, given weekly to solid tumour patients

PR-104 a bioreductive pre-prodrug combined with gemcitabine or docetaxel in a phase Ib study of patients with advanced solid tumours

Phase I drug-interaction study of effects of calcium and magnesium infusions on oxaliplatin pharmacokinetics and acute neurotoxicity in colorectal cancer patients

Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability

Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons

The Effects of Synthetically Modified Natural Compounds on ABC Transporters

Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test

5,6-Dimethylxanthenone-4-Acetic Acid in the Treatment of Refractory Tumors: a Phase I Safety Study of a Vascular Disrupting Agent

Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer

Differential Expression of ATP7A, ATP7B and CTR1 in Adult Rat Dorsal Root Ganglion Tissue

Muscle ultrasound in the assessment of oxaliplatin-induced neurotoxicity

New-generation platinum drugs in the treatment of cisplatin-resistant cancers

Hormone Resistance in Two MCF-7 Breast Cancer Cell Lines is Associated with Reduced mTOR Signaling, Decreased Glycolysis, and Increased Sensitivity to Cytotoxic Drugs

Role of platinum DNA damage‐induced transcriptional inhibition in chemotherapy‐induced neuronal atrophy and peripheral neurotoxicity

Oxaliplatin-Induced Loss of Phosphorylated Heavy Neurofilament Subunit Neuronal Immunoreactivity in Rat Drg Tissue

Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry

Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity

Phase IB Trial of the Anti-Cancer Stem Cell DLL4-Binding Agent Demcizumab with Pemetrexed and Carboplatin as First-Line Treatment of Metastatic Non-Squamous NSCLC

Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

Incomplete uptake of EGFR mutation testing and its impact on estimation of mutation prevalence in patients with non-squamous NSCLC: A population-based study in New Zealand

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