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An electrostatic mechanism for Ca2+-mediated regulation of gap junction channels

Nature communications, 2016-01, Vol.7 (1), p.8770-12, Article 8770

2016

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Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry

Nature communications, 2023-07, Vol.14 (1), p.4368-16, Article 4368

2023

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A Steric “Ball-and-Chain” Mechanism for pH-Mediated Regulation of Gap Junction Channels

Cell reports (Cambridge), 2020-04, Vol.31 (3), p.107482-107482, Article 107482

2020

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A model for how Gβγ couples Gα to GPCR

The Journal of general physiology, 2022-05, Vol.154 (5), p.1

McIntire, William E

2022

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Glycosylation of CaV3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes

Frontiers in cellular neuroscience, 2020-12, Vol.14, p.605312-605312

2020

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Inhibition of a Background Potassium Channel by Gq Protein α-Subunits

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3422-3427

2006

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Function and dynamics of macromolecular complexes explored by integrative structural and computational biology

Current opinion in structural biology, 2014-08, Vol.27, p.138-148

2014

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Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Cav3.2 T-Type Calcium Channels

Diabetes (New York, N.Y.), 2013-11, Vol.62 (11), p.3828-3838

2013

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Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels

Diabetes (New York, N.Y.), 2013-11, Vol.62 (11), p.3828-3838

2013

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Functional TASK-3–Like Channels in Mitochondria of Aldosterone-Producing Zona Glomerulosa Cells

Hypertension (Dallas, Tex. 1979), 2017-08, Vol.70 (2), p.347-356

2017

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Inhibition of mammalian Gq protein function by local anesthetics

Anesthesiology (Philadelphia), 2002-12, Vol.97 (6), p.1451-1457

2002

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Protein Kinase A Activity Controls the Regulation of T-type CaV3.2 Channels by Gβγ Dimers

The Journal of biological chemistry, 2009-03, Vol.284 (12), p.7465-7473

2009

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Ligand-Receptor-G-Protein Molecular Assemblies on Beads for Mechanistic Studies and Screening by Flow Cytometry

Molecular pharmacology, 2003-11, Vol.64 (5), p.1227-1238

2003

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Differential Sensitivity of P-Rex1 to Isoforms of G Protein βγ Dimers

The Journal of biological chemistry, 2006-01, Vol.281 (4), p.1913-1920

2006

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Binding of β4γ5 by Adenosine A1 and A2A Receptors Determined by Stable Isotope Labeling with Amino Acids in Cell Culture and Mass Spectrometry

Biochemistry (Easton), 2011-01, Vol.50 (2), p.207-220

2011

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Structural Determinants Involved in the Formation and Activation of G Protein βγ Dimers

Neuro-Signals, 2009-02, Vol.17 (1), p.82-99

McIntire, William E.

2009

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Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein βγ subunits

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9771-9776

2000

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Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides

Analytical biochemistry, 2007-12, Vol.371 (1), p.10-20

2007

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Role of the Isoprenyl Pocket of the G Protein βγ Subunit Complex in the Binding of Phosducin and Phosducin-like Protein

Biochemistry (Easton), 2004-05, Vol.43 (19), p.5651-5660

2004

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Influence of Differential Stability of G Protein βγ Dimers Containing the γ11 Subunit on Functional Activity at the M1 Muscarinic Receptor, A1 Adenosine Receptor, and Phospholipase C-β

Biochemistry (Easton), 2006-09, Vol.45 (38), p.11616-11631

2006

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Mechanism of PH Gating in Cx26 Gap Junction Channels Revealed by cryoEM, Crosslinking and HDX

Biophysical journal, 2018-02, Vol.114 (3), p.134a-134a

2018

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Glycosylation of Ca V 3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes

Frontiers in cellular neuroscience, 2020, Vol.14, p.605312

2020

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Structural Determinants Involved in the Formation and Activation of G Protein beta gamma Dimers

Neuro-Signals, 2009-02, Vol.17 (1), p.82-99

McIntire, William E

2009

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Purification of G protein isoforms GOA and GOC from bovine brain

Methods in Enzymology, 2002, Vol.344, p.176-185

2002

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Characterization of deamidated G protein subunits

Methods in Enzymology, 2002, Vol.344, p.481-505

2002

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An electrostatic mechanism for Ca2+-mediated regulation of gap junction channels

Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry

A Steric “Ball-and-Chain” Mechanism for pH-Mediated Regulation of Gap Junction Channels

A model for how Gβγ couples Gα to GPCR

Glycosylation of CaV3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes

Inhibition of a Background Potassium Channel by Gq Protein α-Subunits

Function and dynamics of macromolecular complexes explored by integrative structural and computational biology

Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Cav3.2 T-Type Calcium Channels

Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels

Functional TASK-3–Like Channels in Mitochondria of Aldosterone-Producing Zona Glomerulosa Cells

Inhibition of mammalian Gq protein function by local anesthetics

Protein Kinase A Activity Controls the Regulation of T-type CaV3.2 Channels by Gβγ Dimers

Ligand-Receptor-G-Protein Molecular Assemblies on Beads for Mechanistic Studies and Screening by Flow Cytometry

Differential Sensitivity of P-Rex1 to Isoforms of G Protein βγ Dimers

Binding of β4γ5 by Adenosine A1 and A2A Receptors Determined by Stable Isotope Labeling with Amino Acids in Cell Culture and Mass Spectrometry

Structural Determinants Involved in the Formation and Activation of G Protein βγ Dimers

Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein βγ subunits

Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides

Role of the Isoprenyl Pocket of the G Protein βγ Subunit Complex in the Binding of Phosducin and Phosducin-like Protein

Influence of Differential Stability of G Protein βγ Dimers Containing the γ11 Subunit on Functional Activity at the M1 Muscarinic Receptor, A1 Adenosine Receptor, and Phospholipase C-β

Mechanism of PH Gating in Cx26 Gap Junction Channels Revealed by cryoEM, Crosslinking and HDX

Glycosylation of Ca V 3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes

Structural Determinants Involved in the Formation and Activation of G Protein beta gamma Dimers

Purification of G protein isoforms GOA and GOC from bovine brain

Characterization of deamidated G protein subunits

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