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Regulation of Numb isoform expression by activated ERK signaling

Oncogene, 2016-09, Vol.35 (39), p.5202-5213

2016

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Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia

Leukemia, 2013-08, Vol.27 (8), p.1666-1676

2013

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Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain

The Journal of biological chemistry, 2003-06, Vol.278 (25), p.23196-23203

2003

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Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

Oncogene, 1998-12, Vol.17 (24), p.3073-3082

1998

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Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B

Developmental cell, 2002-04, Vol.2 (4), p.497-503

2002

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Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

Nature (London), 2002-03, Vol.416 (6877), p.143-149

2002

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Integrin β Cytoplasmic Domain Interactions with Phosphotyrosine-Binding Domains: A Structural Prototype for Diversity in Integrin Signaling

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2272-2277

2003

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The role of Gads in hematopoietic cell signalling

Oncogene, 2001-10, Vol.20 (44), p.6284-6290

2001

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Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells

Oncogene, 1999-03, Vol.18 (10), p.1867-1879

1999

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

Molecular and Cellular Biology, 1992-03, Vol.12 (3), p.991-997

1992

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The γ-Secretase-Generated Intracellular Domain of β-Amyloid Precursor Protein Binds Numb and Inhibits Notch Signaling

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (10), p.7102-7107

2002

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The hematopoietic-specific adaptor protein Gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

Current biology, 1999-01, Vol.9 (2), p.67-75

1999

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Neuralized functions as an E3 ubiquitin ligase during Drosophila development

Current biology, 2001-10, Vol.11 (21), p.1675-1679

2001

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Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain

The Journal of biological chemistry, 1999-11, Vol.274 (46), p.33097-33104

1999

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Gads/Grb2-Mediated Association with LAT Is Critical for the Inhibitory Function of Gab2 in T Cells

Molecular and Cellular Biology, 2003-04, Vol.23 (7), p.2515-2529

2003

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A Novel PTB-PDZ Domain Interaction Mediates Isoform-specific Ubiquitylation of Mammalian Numb

The Journal of biological chemistry, 2004-05, Vol.279 (20), p.20807-20815

2004

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LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2

Molecular and cellular neuroscience, 2005-10, Vol.30 (2), p.238-248

2005

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Interaction of Linker for Activation of T Cells with Multiple Adapter Proteins in Platelets Activated by the Glycoprotein VI-selective Ligand, Convulxin

The Journal of biological chemistry, 2000-10, Vol.275 (43), p.33427-33434

2000

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Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

Current biology, 1996-09, Vol.6 (9), p.1134-1145

1996

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Functional Cooperation between c-Cbl and Src-Like Adaptor Protein 2 in the Negative Regulation of T-Cell Receptor Signaling

Molecular and Cellular Biology, 2002-06, Vol.22 (12), p.4241-4255

2002

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Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

The Journal of immunology (1950), 2002-04, Vol.168 (7), p.3173-3180

2002

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The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.9179-9187

1998

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The Adaptor Protein Gads (Grb2-Related Adaptor Downstream of Shc) Is Implicated in Coupling Hemopoietic Progenitor Kinase-1 to the Activated TCR

The Journal of immunology (1950), 2000-08, Vol.165 (3), p.1417-1426

2000

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Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v

Oncogene, 2003-01, Vol.22 (2), p.266-273

2003

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Association of Grb2, Gads, and Phospholipase C- gamma 1 with Phosphorylated LAT Tyrosine Residues: Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling

The Journal of biological chemistry, 2000-07, Vol.275 (30), p.23355-23361

2000

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Regulation of Numb isoform expression by activated ERK signaling

Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia

Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

Integrin β Cytoplasmic Domain Interactions with Phosphotyrosine-Binding Domains: A Structural Prototype for Diversity in Integrin Signaling

The role of Gads in hematopoietic cell signalling

Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

The γ-Secretase-Generated Intracellular Domain of β-Amyloid Precursor Protein Binds Numb and Inhibits Notch Signaling

The hematopoietic-specific adaptor protein Gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

Neuralized functions as an E3 ubiquitin ligase during Drosophila development

Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain

Gads/Grb2-Mediated Association with LAT Is Critical for the Inhibitory Function of Gab2 in T Cells

A Novel PTB-PDZ Domain Interaction Mediates Isoform-specific Ubiquitylation of Mammalian Numb

LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2

Interaction of Linker for Activation of T Cells with Multiple Adapter Proteins in Platelets Activated by the Glycoprotein VI-selective Ligand, Convulxin

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

Functional Cooperation between c-Cbl and Src-Like Adaptor Protein 2 in the Negative Regulation of T-Cell Receptor Signaling

Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX

The Adaptor Protein Gads (Grb2-Related Adaptor Downstream of Shc) Is Implicated in Coupling Hemopoietic Progenitor Kinase-1 to the Activated TCR

Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v

Association of Grb2, Gads, and Phospholipase C- gamma 1 with Phosphorylated LAT Tyrosine Residues: Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling

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