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Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

Diabetes (New York, N.Y.), 2002, Vol.51 (1), p.7-18

MCGARRY, J. Denis

2002

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Prolonged Inhibition of Muscle Carnitine Palmitoyltransferase-1 Promotes Intramyocellular Lipid Accumulation and Insulin Resistance in Rats

Diabetes (New York, N.Y.), 2001-01, Vol.50 (1), p.123-130

2001

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The Composition of Dietary Fat Directly Influences Glucose-Stimulated Insulin Secretion in Rats

Diabetes (New York, N.Y.), 2002-06, Vol.51 (6), p.1825-1833

2002

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Bulk magnetic susceptibility effects on the assessment of intra- and extramyocellular lipids in vivo

Magnetic resonance in medicine, 2002-03, Vol.47 (3), p.607-610

2002

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Carnitine Biosynthesis Metabolism, and Functions

Frenkel, Rene

1, 1980

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Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo

American journal of physiology: endocrinology and metabolism, 1999-05, Vol.276 (5), p.E977-E989

1999

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What If Minkowski Had Been Ageusic? An Alternative Angle on Diabetes

Science (American Association for the Advancement of Science), 1992-10, Vol.258 (5083), p.766-770

McGarry, J. Denis

1992

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Knockout Mice Lacking Steroidogenic Factor 1 Are a Novel Genetic Model of Hypothalamic Obesity

Endocrinology (Philadelphia), 2002-02, Vol.143 (2), p.607-614

2002

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Metabolic Coupling Factors in Pancreatic β-Cell Signal Transduction

Annual review of biochemistry, 1995, Vol.64 (1), p.689-719

1995

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Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

Diabetes (New York, N.Y.), 1998-10, Vol.47 (10), p.1613

1998

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The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis

European journal of biochemistry, 1997-02, Vol.244 (1), p.1-14

1997

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Glucose-fatty acid interactions in health and disease

The American journal of clinical nutrition, 1998-03, Vol.67 (3), p.500S-504S

McGarry, JD

1998

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Molecular characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme

Journal of lipid research, 2001-07, Vol.42 (7), p.1134-1142

2001

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Fatty Acids Rapidly Induce the Carnitine Palmitoyltransferase I Gene in the Pancreatic β-Cell Line INS-1

The Journal of biological chemistry, 1997-01, Vol.272 (3), p.1659-1664

1997

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Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes

American journal of physiology: endocrinology and metabolism, 2001-02, Vol.280 (2), p.E238-E247

2001

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Chemical sympathectomy alters regulation of body weight during prolonged ICV leptin infusion

American journal of physiology: endocrinology and metabolism, 2003-04, Vol.284 (4), p.E778-E787

2003

Volltextzugriff (PDF)

More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling

Diabetes (New York, N.Y.), 1994-07, Vol.43 (7), p.878

1994

Volltextzugriff (PDF)

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes

Biochemical journal, 1997-10, Vol.327 ( Pt 1) (1), p.225-231

1997

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Mitochondrial Carnitine Palmitoyltransferase I Isoform Switching in the Developing Rat Heart

The Journal of biological chemistry, 1995-04, Vol.270 (15), p.8952-8957

1995

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The metabolic derangements and treatment of diabetic ketoacidosis

The New England journal of medicine, 1983-07, Vol.309 (3), p.159

1983

Volltextzugriff (PDF)

Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues

Biochemical journal, 1998-11, Vol.335 ( Pt 3) (3), p.513-519

1998

Volltextzugriff (PDF)

Elucidation of the Mechanism by Which (+)-Acylcarnitines Inhibit Mitochondrial Fatty Acid Transport

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.36766-36768

2000

Volltextzugriff (PDF)

The N-terminal Domain of Rat Liver Carnitine Palmitoyltransferase 1 Mediates Import into the Outer Mitochondrial Membrane and Is Essential for Activity and Malonyl-CoA Sensitivity

The Journal of biological chemistry, 1998-11, Vol.273 (45), p.29896-29904

1998

Volltextzugriff (PDF)

Chemical sympathectomy alters regulation of body weight during prolonged ICV leptin infusion

American journal of physiology: endocrinology and metabolism, 2003-04, Vol.47 (4), p.E778-E787

2003

Volltextzugriff (PDF)

Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM

Diabetes (New York, N.Y.), 1997-03, Vol.46 (3), p.408

1997

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Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

Prolonged Inhibition of Muscle Carnitine Palmitoyltransferase-1 Promotes Intramyocellular Lipid Accumulation and Insulin Resistance in Rats

The Composition of Dietary Fat Directly Influences Glucose-Stimulated Insulin Secretion in Rats

Bulk magnetic susceptibility effects on the assessment of intra- and extramyocellular lipids in vivo

Carnitine Biosynthesis Metabolism, and Functions

Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo

What If Minkowski Had Been Ageusic? An Alternative Angle on Diabetes

Knockout Mice Lacking Steroidogenic Factor 1 Are a Novel Genetic Model of Hypothalamic Obesity

Metabolic Coupling Factors in Pancreatic β-Cell Signal Transduction

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis

Glucose-fatty acid interactions in health and disease

Molecular characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme

Fatty Acids Rapidly Induce the Carnitine Palmitoyltransferase I Gene in the Pancreatic β-Cell Line INS-1

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes

Chemical sympathectomy alters regulation of body weight during prolonged ICV leptin infusion

More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes

Mitochondrial Carnitine Palmitoyltransferase I Isoform Switching in the Developing Rat Heart

The metabolic derangements and treatment of diabetic ketoacidosis

Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues

Elucidation of the Mechanism by Which (+)-Acylcarnitines Inhibit Mitochondrial Fatty Acid Transport

The N-terminal Domain of Rat Liver Carnitine Palmitoyltransferase 1 Mediates Import into the Outer Mitochondrial Membrane and Is Essential for Activity and Malonyl-CoA Sensitivity

Chemical sympathectomy alters regulation of body weight during prolonged ICV leptin infusion

Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM

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